Rchr
J-GLOBAL ID:200901011635814187
Update date: Nov. 15, 2024
Ogawa Takehiko
オガワ タケヒコ | Ogawa Takehiko
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.tsurumi.yokohama-cu.ac.jp/proteome/ogawa/
Research field (2):
Medical biochemistry
, Urology
Research keywords (7):
spermatogenesis
, 再生医学
, アンドロロジー
, 男性不妊症
, regenerative medicine
, andrology
, Male infertility
Research theme for competitive and other funds (21):
- 2022 - 2025 Developing an in vitro system for human spermatogenesis
- 2018 - 2022 Establishment of in vitro spermatogenesis with high integrity
- 2017 - 2020 Investigation of bone microenvironment using 3D-organoid model.
- 2018 - 2019 動物における配偶子産生システムの制御
- 2015 - 2018 International joint research on gamete formation through the cutting-edge analysis system
- 2013 - 2018 Mechanisms regulating gamete formation in animals
- 2013 - 2018 in vitroにおいて継続的に精子を産生する新規培養系の開発
- 2014 - 2017 Development of in vitro embryo culture system based-on microfluidics for artificial reproductive technology
- 2012 - 2015 器官培養法を用いたヒトin vitro精子形成法の開発
- 2008 - 2014 Regulatory Mechanism of Gamete Stem Cells
- 2008 - 2013 培養系を用いたマウスGSC/ニッチ・システムの解明と分化誘導系の開発
- 2009 - 2012 精子幹細胞からの精子形成培養法の開発
- 2006 - 2008 培養精原幹細胞を用いた ex vivo 精子形成再生法の開発
- 2007 - 2008 霊長類の生殖幹細胞株(GS細胞)樹立にむけた幹細胞純化と異種移植系の開発
- 2003 - 2004 Searching for culture condition optimal for proliferation of spermatogonial stem cells
- 2001 - 2002 Searching of factors facilitate spermatogonial stem cell proliferation (Investigation with transplantation and in vitro analysis)
- 2002 - 再生医学(腎再生、膀胱再生)
- 1999 - 2000 Analysis of spermatogonial proliferation with technique of spermatogonial transplantation-A trial for improving spermatogenic activity
- 1995 - 精原幹細胞の培養とin vitro 精子形成
- 精巣腫瘍の細胞学的研究
- 男子不妊症
Show all
Papers (187):
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Kiyoshi Hashimoto, Hiroshi Arakawa, Rikako Imamura, Takuya Nishimura, Satoshi Kitajima, Takuya Sato, Kazuhide Makiyama, Takehiko Ogawa, Satoshi Yokota. A novel alternative method for long-term evaluation of male reproductive toxicity and its recovery using a pre-pubertal mouse testis organ culture system. Journal of Applied Toxicology. 2024. 44. 5. 784-793
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Kiyoshi Hashimoto, Hiroshi Arakawa, Rikako Imamura, Takuya Nishimura, Satoshi Kitajima, Takuya Sato, Kazuhide Makiyama, Takehiko Ogawa, Satoshi Yokota. Testis organ culture system capable of evaluating testicular toxicity. 2023
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Kiyoshi Hashimoto, Hisakazu Odaka, Yu Ishikawa-Yamauchi, Shino Nagata, Hiroko Nakamura, Hiroshi Kimura, Takuya Sato, Kazuhide Makiyama, Takehiko Ogawa. Culture-space control is effective in promoting haploid cell formation and spermiogenesis in vitro in neonatal mice. Scientific Reports. 2023. 13. 1
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Takafumi Matsumura, Kumiko Katagiri, Tatsuma Yao, Yu Ishikawa-Yamauchi, Shino Nagata, Kiyoshi Hashimoto, Takuya Sato, Hiroshi Kimura, Takashi Shinohara, Makoto Sanbo, et al. Generation of rat offspring using spermatids produced through in vitro spermatogenesis. SCIENTIFIC REPORTS. 2023. 13. 1
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Xuemin Feng, Takafumi Matsumura, Yuki Yamashita, Takuya Sato, Kiyoshi Hashimoto, Hisakazu Odaka, Yoshinori Makino, Yuki Okada, Hiroko Nakamura, Hiroshi Kimura, et al. In vitro spermatogenesis in isolated seminiferous tubules of immature mice. PLOS ONE. 2023. 18. 4. e0283773-e0283773
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MISC (34):
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福永久典, 神長輝一, 宇佐美徳子, 小川毅彦, PRISE Kevin, 横谷明徳. Application of an ex vivo organ culture method to investigate impacts on spermatogenesis following exposure to intensity- and distribution-modulated radiation fields. 量子ビームサイエンスフェスタ(Web). 2018. 2017
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古目谷 暢, 林 功晃, 山中 弘行, 三條 博之, 小島 一晃, 片桐 久美子, 佐藤 卓也, 矢尾 正祐, 木村 啓志, 藤井 輝夫, et al. 精子形成を長期間維持できるin vitro精巣組織培養システムの開発. 日本生殖内分泌学会雑誌. 2016. 21. 27-31
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Hiroki Ito, Takashi Kawahara, Hideyuki Terao, Junichi Matsuzaki, Takehiko Ogawa, Masahiro Yao, Yoshinobu Kubota. Reply by the authors. Urology. 2013. 81. 1. 217
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Hiroki Ito, Takashi Kawahara, Hideyuki Terao, Junichi Matsuzaki, Takehiko Ogawa, Masahiro Yao, Yoshinobu Kubota. Re: Ito et al.: The Most Reliable Preoperative Assessment of Renal Stone Burden as a Predictor of Stone-free Status After Flexible Ureteroscopy With Holmium Laser Lithotripsy: A Single-center Experience (Urology 2012; 80:524-528) Reply. UROLOGY. 2013. 81. 1. 217-217
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佐藤卓也, 小川毅彦. 精子形成不全マウスの精巣組織から培養下での精子産生. 細胞工学. 2013. 32. 2. 212-213
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Education (3):
- 1985 - 1989 Yokohama City University Graduate Graduate School of Medicine
- 1979 - 1985 Yokohama City University
- - 1985 Yokohama City University Faculty of Medicine
Professional career (1):
Committee career (8):
Awards (2):
- 2013/03 - Johnson & Johnson Innovation Award
- 2012/04 - 読売テクノフォーラム ゴールドメダル賞 「培養下での精子形成法の開発」
Association Membership(s) (1):
日本泌尿器科学会 日本再生医療学会 日本生殖医学会 日本癌学会 日本分子生物学学会
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