Oku Masahide

オクマサヒデ | Oku Masahide

Affiliation and department：
Job title：准教授

Research field (2)： Applied microbiology , Cell biology

Research keywords (4)： lipid droplet , yeast , vacuole , autophagy

Research theme for competitive and other funds (14)：

2022 - 2025 Screening of the proteins involved in uptake of ubiquinone in Saccharomyces cerevisiae using synthetic ubiquinone probes
2019 - 2024 ミクロオートファジーの作動・制御機構
2020 - 2023 Regulation mechanism of yeast lipid droplet quantity in response to environmental changes
2016 - 2019 Elucidation of molecular mechanism of autophagy and lipid metabolism supporting soundness of organelles
2016 - 2018 Molecular mechanism of survival strategy of phyllosphere methylotrophic yeasts exposed to harsh environmental changes and stresses

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Papers (56)：

Yasuyoshi Sakai, Masahide Oku. ATG and ESCRT control multiple modes of microautophagy. FEBS Letters. 2024
Shin Ohsawa, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai. Regulation of Peroxisome Homeostasis by Post-Translational Modification in the Methylotrophic Yeast Komagataella phaffii. Frontiers in cell and developmental biology. 2022. 10. 887806-887806
Shin Ohsawa, Koichi Inoue, Takahiro Isoda, Masahide Oku, Hiroya Yurimoto, Yasuyoshi Sakai. The methanol sensor Wsc1 and MAPK Mpk1 suppress degradation of methanol-induced peroxisomes in methylotrophic yeast. Journal of Cell Science. 2021. 134. 9
Yuichi Abe, Masanori Honsho, Ryoko Kawaguchi, Takashi Matsuzaki, Yayoi Ichiki, Masashi Fujitani, Kazushirou Fujiwara, Masaaki Hirokane, Masahide Oku, Yasuyoshi Sakai, et al. A peroxisome deficiency-induced reductive cytosol state up-regulates the brain-derived neurotrophic factor pathway. The Journal of biological chemistry. 2020. 295. 16. 5321-5334
Pang Y, Yamamoto H, Sakamoto H, Oku M, Mutungi JK, Sahani MH, Kurikawa Y, Kita K, Noda NN, Sakai Y, et al. Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system. Nature structural & molecular biology. 2019. 26. 4. 289-296

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MISC (108)：

有馬ゆみ, 中村元春, 中辻拓実, 奥公秀, 白石晃將, 阪井康能. Analysis of KpATG14 required for pexophagy in methylotrophic yeast Komagataella phaffii. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
石垣颯斗, 白石晃將, 光部雅俊, 奥公秀, 阪井康能. Role of ESCRTs in micropexophagy of the methylotrophic yeast Komagataella phaffii. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
光部雅俊, 中辻拓実, 齋藤敬, 奥公秀, 白石晃將, 阪井康能. Regulatory mechanism of autophagy by non-covalent complex Atg12-Atg5 in the yeast Komagataella phaffii. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
光部雅俊, 中辻拓実, 白石晃將, 奥公秀, 阪井康能. Regulation of autophagy by non-covalent Atg12-Atg5 complex in yeast Komagataella phaffii. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
安部真人, 千ヶ崎修平, 奥公秀, 阪井康能, 三芳秀人. 合成リゾカルジオリピン類縁体のトランスアシラーゼtafazzinに対する阻害効果. 脂質生化学研究. 2019. 61

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Books (1)：

Lectures and oral presentations (16)：

The dynamics of lipid droplets at the crossroads between autophagy and lipolysis
(2018)
脂肪滴量制御におけるオートファジーおよびESCRTタンパク質の機能
(第123回日本解剖学会総会・全国学術集会 2018)
ミクロオートファジーの分子機構,生理機能の多様性
(日本農芸化学会2018年度大会シンポジウム 2018)
酵母脂肪滴のダイナミクスに関わるオートファジー
(第8回愛媛微生物学ネットワーク(NAME)・フォーラム 2017)
酵母液胞と脂肪滴との機能連関
(第81回酵母研究会講演会 2016)

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Education (6)：

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Professional career (2)：

Association Membership(s) (2)：

日本分子生物学会 , 日本農芸化学会

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