Rchr
J-GLOBAL ID：200901012949975025   Update date: Oct. 30, 2024

Kawashima Hidekazu

Kawashima Hidekazu | Kawashima Hidekazu
Affiliation and department：
Kyoto Pharmaceutical University Radioisotope Research Center

About Kyoto Pharmaceutical University Radioisotope Research Center


Job title： Associate Professor
Research field  (2)： Radiology ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (7)： SPECT ,  PET ,  Translational Research ,  Theranostics ,  Nuclear Medicine ,  Molecular imaging ,  Radiopharmaceutical Science
Research theme for competitive and other funds  (24)：
  • 2023 - 2028 Development of medical Tc drugs using Tc isotopes and development of a medical gamma-ray camera for clinical applications
  • 2023 - 2026 骨格筋の新機能としての老廃物除去機能を解明する
  • 2021 - 2024 Elucidation of mechanisms underlying lifestyle-related diseases and malignant tumors based on in vivo imaging of scavenger receptors
  • 2019 - 2022 Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myeloma
  • 2017 - 2019 Development and application of novel chemical compounds to materialize the cancer theranostics
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Papers (105)：
  • Yuto Kondo, Hiroyuki Kimura, Mamiko Tanaka, Yasunao Hattori, Hidekazu Kawashima, Kazuhiro Takahashi, Hiroyuki Yasui. Mechanistic Insights into the Effect of Sodium Iodide on Copper-Mediated Iododeboronation. Chemistry - A European Journal. 2024
  • Michi Izawa, Hidekazu Kawashima, Yui Okuno, Junna Nakaya, Mayuko Takeda, Koki Harada, Yuri Yamada, Kaneyasu Nishimura, Keiichi Ishihara, Satoshi Akiba, et al. Radioimaging Foam Cells Infiltrating Atherosclerotic Plaques in Mice Using 125I-labeled oxLDL as a Radiotracer. Molecular Imaging and Biology. 2024
  • Kentaro Otani, Tsutomu Zeniya, Hidekazu Kawashima, Tetsuaki Moriguchi, Atsushi Nakano, Chunlei Han, Shunsuke Murata, Kunihiro Nishimura, Kazuhiro Koshino, Kenichi Yamahara, et al. Spatial and temporal tracking of multi-layered cells sheet using reporter gene imaging with human sodium iodide symporter: a preclinical study using a rat model of myocardial infarction. European journal of nuclear medicine and molecular imaging. 2024
  • Yuto Kondo, Hiroyuki Kimura, Ryota Chisaka, Yasunao Hattori, Hidekazu Kawashima, Hiroyuki Yasui. One-pot two-step radioiodination based on copper-mediated iododeboronation and azide-alkyne cycloaddition reaction. Chemical Communications. 2024. 60. 6. 714-717
  • Marina Omokawa, Hiroyuki Kimura, Yuichi Hatsukawa, Hidekazu Kawashima, Kazuaki Tsukada, Yusuke Yagi, Yuki Naito, Hiroyuki Yasui. Production and synthesis of a novel 191Pt-labeled platinum complex and evaluation of its biodistribution in healthy mice. Bioorganic & Medicinal Chemistry. 2024. 97. 117557-117557
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MISC (236)：
  • 面川真里奈, 木村寛之, 木村寛之, 初川雄一, 河嶋秀和, 塚田和明, 屋木裕亮, 内藤行喜, 安井裕之. Synthesis and biological evaluation of a novel sugar-conjugated platinum complex having a tumor-targeting effect and 191Pt labeled complex. 日本薬学会年会要旨集(Web). 2024. 144th
  • 原史子, 河嶋秀和, 堀山志朱代, 屋木祐亮, 高田慎也, 木村寛之, 萩森政頼. Development of peptide-based probes targeting Mucin 16 for diagnostic imaging. 日本薬学会年会要旨集(Web). 2024. 144th
  • 對馬結太, 松岡将宏, 笹谷典太, 砂口尚輝, 河嶋秀和, 兵藤一行, 湯浅哲也, 銭谷勉. Improvement of image quality of x-ray fluorescence computed tomography by using deep image prior. 量子ビームサイエンスフェスタ(Web). 2023. 2022
  • 細見謙登, 河嶋秀和, 中野厚史, 垣野明美, 岡松優子, 山下裕騎, 笹岡真衣, 増田大作, 山下静也, 細田洋司, et al. nanoSPECTによる褐色脂肪組織へのCD36を介した酸化LDL集積機構の発見. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2023. 55th
  • 近藤悠斗, 木村寛之, 河嶋秀和, 服部恭尚, 安井裕之. Copper-mediated one-pot radioiodination on a resin. 日本薬学会年会要旨集(Web). 2023. 143rd
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Books (3)：
  • 臨床放射薬学 : 薬学領域における放射化学の理論と実践
    京都廣川書店 2022 ISBN:9784910844039
  • Handbook of in vivo chemistry in mice : from lab to living system
    Wiley-VCH 2020 ISBN:9783527344321
  • Resistance to Ibritumomab in Lymphoma
    2018
Lectures and oral presentations  (33)：
  • CD36を介した酸化LDLのマウス褐色脂肪組織への取込み
    (日本薬学会 第144年会 2024)
  • TNBCの早期診断を目的としたMUC16指向性ペプチドプローブの合成
    (日本薬学会 第144年会 2024)
  • マウスにおける放射性ヨウ素標識酸化LDLを用いた動脈硬化巣の検出
    (日本薬学会 第144年会 2024)
  • 抗腫瘍効果を有する新規糖連結白金錯体と191Pt標識体の合成および生物学的評価
    (日本薬学会 第144年会 2024)
  • 希薄条件下における銅触媒下脱ホウ素ヨウ素化反応
    (日本薬学会 第144年会 2024)
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Education (2)：
  • - 2002 Kyoto University Graduate School of Pharmaceutical Sciences
  • - 1997 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
  • Ph. D. (Pharmaceutical Sciences) (Kyoto University)
Work history (6)：
  • 2016/01 - 現在 Kyoto Pharmaceutical University Radioisotope Research Center Associate Professor
  • 2014/01 - 2015/12 Health Sciences University of Hokkaido Division of Radiopharmaceutical Chemistry, School of Pharmaceutical Sciences Associate Professor
  • 2010/04 - 2013/12 National Cerebral and Cardiovascular Center, Research Institute Laboratory of Diagnostic Molecular Imaging, Department of Investigative Radiology Chief
  • 2004/02 - 2010/03 Graduate School of Pharmaceutical Sciences Department of Patho-Functional Bioanalysis Research Scientist
  • 2004/02 - 2010/03 Graduate School of Medicine, Kyoto University Department of Nuclear Medicine and Diagnostic Imaging Assistant Professor
Show all
Association Membership(s) (8)：
日本分子イメージング学会 ,  日本核医学会 ,  日本薬学会 ,  Society of Radiopharmaceutical Sciences ,  World Molecular Imaging Society ,  Society of Nuclear Medicine and Molecular Imaging ,  放射性薬品科学研究会 ,  日本薬学教育学会
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