Rchr
J-GLOBAL ID:200901012977889975
Update date: Nov. 05, 2024
Shimizu Yusuke
シミズ ユウスケ | Shimizu Yusuke
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://www.ryukyuprs.com/index.html
Research field (2):
Plastic and reconstructive surgery
, Cell biology
Research keywords (7):
Plastic Reconstructive Surgery
, Microsurgery
, 眼瞼形成
, Stem Cell
, Regenerative Medicine
, 脊髄虚血
, 下肢運動障害
Research theme for competitive and other funds (34):
- 2024 - 2029 腸オルガノイド細胞による立体構造体を用いた炎症性腸疾患に対する新たな治療法の確立
- 2024 - 2027 皮下膵島移植の成績を向上する3D膵島細胞シートの開発
- 2024 - 2027 Optimizing lymphatic vessel regeneration through adipose-derived stromal cell-mediated organelle transfer
- 2024 - 2027 Three-dimensional Morphological Visualization of Human Collective Lymphatic Vessels to Elucidate Lymphedema Mechanisms
- 2024 - 2027 再生医療等製品(Muse細胞製剤)の原材料としての歯髄細胞の可能性
- 2024 - 2027 多層化脂肪幹細胞シートを用いた肛門括約筋再生に関する研究
- 2022 - 2025 Development of a new microscopic observation method for cross-sectional observation of living cell membrane structures
- 2022 - 2025 Development of new preventive method for postoperative paraplegia of thoracoabdominal aorta using exosomes
- 2022 - 2025 リンパ浮腫治療のための脂肪間質細胞改変型”Designer Cells”の開発
- 2022 - 2025 沖縄を拠点とするエクソソーム精製事業の発展と医療機器・医薬品産業への応用
- 2022 - 2025 液性因子の機能を保持した乾燥粉末化技術の確立と製造ラインの県内構築
- 2022 - 2025 幹細胞治療を通じた沖縄再生医療・スポーツ産業の発展
- 2021 - 2024 Implementation of human cell resource supply system from University of the Ryukyus
- 2019 - 2023 脂肪幹細胞由来神経細胞による胸腹部大動脈術後虚血性対麻痺に対する新規治療法の開発
- 2019 - 2022 強固な骨接合を促進する軟骨再生マイクロパターン基材の開発
- 2020 - 2022 高純度エクソソーム(細胞外小胞)生産技術の開発と医療・化粧品産業への応用
- 2020 - 2022 再生医療に係る治験等実施体制の構築
- 2020 - 2021 細胞ストックを実用化するための基盤構築事業
- 2019 - 2021 幹細胞抽出培養シートの臨床応用に向けた研究開発
- 2018 - 2021 Creating a support system for sustainable provision of human allogenic stem cell resources from University of the Ryukyus
- 2016 - 2020 Treatment of old facial paralysis using layered adipose derived stem cell sheets
- 2017 - 2020 再生治療用ナノファイバー素材の開発と幹細胞抽出培養キットの開発
- 2017 - 2020 再生医療産業活性化を目指した脂肪幹細胞ストック事業
- 2018 - 2018 脂肪幹細胞輸送のための技術基盤構築
- 2014 - 2018 Development of the system to assist diagnosis and treatment for disorder of facial movement utilizing computerized three dimensional analysis of facial expression based on video images
- 2017 - 2018 手術や在宅で使用できるポータブル吸引機の事業可能性の調査
- 2016 - 2018 術野付近の視認性を改善するための高機能プラスチック製開創器の開発・事業化
- 2015 - 2018 幹細胞創薬を目指した培養脂肪組織由来幹細胞による再生治療法の開発
- 2013 - 2017 An anatomical study on the venous drainage architecture of the face using fresh frozen cadaver
- 2015 - 2016 高機能プラスチック製手術器具の開発
- 2014 - 2015 医療用手術器具の高機能プラスチック製品の開発
- 2012 - 2015 Development of new protocol for zygoma fracture treatment
- 2011 - 2015 Development of the system to assist diagnosis, treatment and surgical planning for disorder of facial movement utilizing computerized analysis of facial expression based on video images
- 2005 - 2006 Functional analysis of genes that regenerate skin during fetal skin regeneration
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Papers (113):
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Takahiro Hirayama, Yusuke Shimizu, Hidetoshi Kinjo, Shinya Agena, Hitoshi Hirakawa, Hiroyuki Maeda, Mikio Suzuki, Ryogo Kuba, Shohei Ishihara, Naoki Matsuura. Analysis of reconstructed oropharynx shape after total glossolaryngectomy reconstruction using a free rectus abdominis musculocutaneous flap. JPRAS Open. 2024
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Eisaku Takahara, Kota Kamizato, Manabu Kakinohana, Hiroshi Sunami, Yuya Kise, Kojiro Furukawa, Edward Hosea Ntege, Yusuke Shimizu. Subpial transplantation of adipose-derived stem cells alleviates paraplegia in a rat model of aortic occlusion/reperfusion-induced spinal cord infarction. Regenerative Therapy. 2024
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Yusuke Shimizu, Edward Hosea Ntege, Eisaku Takahara, Naoki Matsuura, Rikako Matsuura, Kota Kamizato, Yoshikazu Inoue, Yoshihiro Sowa, Hiroshi Sunami. Adipose-derived stem cell therapy for spinal cord injuries: Advances, challenges, and future directions. Regenerative Therapy. 2024. 26. 508-519
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Yusuke Shimizu, Edward Hosea Ntege, Yoshikazu Inoue, Naoki Matsuura, Hiroshi Sunami, Yoshihiro Sowa. Optimizing mesenchymal stem cell extracellular vesicles for chronic wound healing: Bioengineering, standardization, and safety. Regenerative therapy. 2024. 26. 260-274
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Jumpei Shirakawa, Edward H. Ntege, Masuo Takemura, Sho Miyamoto, Toshihiro Kawano, Chisato Sampei, Hayato Kawabata, Hiroyuki Nakamura, Hiroshi Sunami, Tadayoshi Hayata, et al. Exploring SSEA3 as an emerging biomarker for assessing the regenerative potential of dental pulp-derived stem cells. Regenerative Therapy. 2024. 26. 71-79
more...
MISC (156):
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清水 雄介. 美容外科医が知っておくべき再生医療 知っておきたい再生医療の基礎知識 臨床医がゼロから再生医療研究を始めて. 日本美容外科学会プログラム・抄録集. 2024. 112回. 300-301
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角南寛, 普天間直子, 仲宗根均, 與古田沙耶香, 傳田淳子, 清水雄介. 異方性の高い繊維構造を有する幹細胞抽出培養用の足場の開発. 日本再生医療学会総会(Web). 2024. 23rd
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清水雄介. Current Status of Clinical Application of Adipose Stem Cells at the University of the Ryukyus. 日本再生医療学会総会(Web). 2024. 23rd
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清水雄介. Establishment of human cell material supply system at the University of the Ryukyus. 日本再生医療学会総会(Web). 2024. 23rd
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清水雄介. ゼロからはじめた再生医療-演者の苦労と大切と考える視点-. Aesthetic Dermatology. 2024. 34. 2
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Patents (5):
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脂質二重膜に覆われた微粒子又は細胞外小胞の回収方法および 脂質二重膜に覆われた微粒子又は細胞外小胞の回収キット
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樹脂製手術器具
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コラゲナーゼを用いないで脂肪組織由来幹細胞を分離抽出するための方法、及び脂肪由来幹細胞分離抽出用キット
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医療用鈎
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再生医療用細胞の生産および評価、機能調節する培養基材とその使用方法
Books (4):
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Adipose tissue-derived regenerative cell-based therapies: Current optimisation strategies for effective treatment in aesthetic surgery.
Handbook of Stem Cell Therapy. Springer Nature 2022
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Veins of the face and neck
Anatomy for plastic surgery of the face, head and neck. Thieme Medical Publishers Inc. 2016
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Section 3. Surgery. Surgical treatment of blepharoptosis in myasthenic patients.
Novel Challenges in Myasthenia Gravis. Nova Science Publishers. 2015
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Surgical anatomy of lower leg
Calf Surgery and Leg Contouring. Koonja Publishing Company. 2011
Education (2):
- 2006 - 2010 Keio University
- 1992 - 1998 Keio University School of Medicine
Professional career (1):
Work history (7):
- 2020/09 - 現在 University of the Ryukyus Mirai Bank Director
- 2019/04 - 現在 Univresity of the Ryukyus Assistant Deirector of the Hospital
- 2018/04 - 現在 University of the Ryukyus
- 2015/02 - 2018/03 University of the Ryukyus University Hospital, Faculty of Medicine
- 2014/08 - 2015/01 Keio University School of Medicine
- 2013/04 - 2014/07 Keio University School of Medicine
- 2010/05 - 2013/03 Keio University School of Medicine
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Awards (2):
- 2022 - Best paper for Archives of Plastic Surgery (APS) award
- 2013 - 日本形成外科学会;学術奨励賞
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