Rchr
J-GLOBAL ID：200901013013620060
Update date: Jan. 22, 2025
Suzuki Yuko
スズキ ユウコ | Suzuki Yuko
Affiliation and department：
Research field (4)：
Cardiology
, Hematology and oncology
, Clinical pharmacy
, Physiology
Research keywords (6)：
血栓止血
, 生理学
, 線溶
, 可視化解析
, 蛍光顕微鏡
, 血管内皮細胞
Research theme for competitive and other funds (21)：
- 2024 - 2028 Novel therapeutic strategies for COPD targeting the fibrinolysis inhibitor PAI-1
- 2024 - 2027 血流分配を担う血管制御因子の非侵襲生体機能計測
- 2024 - 2027 Development of prevention method for tyrosine kinase inhibitor for chronic myeloid leukemia-induced vascular occlusion based on visualization of thrombogenicity
- 2024 - 2027 The role of fibrinolytic function in the angiogenic microenvironment of wound healing using vascularized organoids
- 2022 - 2025 線溶制御系破綻時の血栓溶解過程のイメージング解析と検査法の確立による病態解明
- 2022 - 2025 Real-time imaging analysis of hemostatic thrombus stabilization and its failure
- 2021 - 2024 生体内細胞代謝と連動する血管内皮細胞の栄養供給調節の非侵襲・非線形生体観察
- 2020 - 2023 Analysis of coagulation and fibrinolytic functions and vascular endothelium-platelet interaction using disease-specific iPS cells
- 2020 - 2023 COVID-19 感染による血栓症発症・増悪機転の解明と治療介入の可能性の解明
- 2019 - 2022 Understanding in spatio-temporal regulation mechanism of thrombus formation and dissolution for realization of appropriate antithrombotic therapy
- 2017 - 2020 Vasa Vasorum in Abdominal Aortic Aneurysm
- 2016 - 2019 Various reguratory mechanisms of activated-platelet' memberane-based activation of fibrinolysis.
- 2015 - 2018 The intrinsic roles of human PAI-1 in adipocyte differentiation and function with using patient-derived iPS cells.
- 2013 - 2016 Elucidation of intrinsic fibrinolytic activities potentiated vascular endothelial cells and its possibility in prophylaxis of thrombotic disease
- 2012 - 2015 Role of phosphatidylserine on activated platelets on tissue factor initiated blood coagulation
- 2012 - 2015 Generation of iPS cells from PAI-1 deficient patient and differentiation into mature cells
- 2010 - 2012 Imaging analysis of the role of newly proposed cell surface-associated fibrinolysis mechanism in the regulation of endothelial barrier function.
- 2009 - 2011 Imaging analysis of phosphatidylserine-evoked initiation of coagulation cascade on activated platelets surface.
- 2007 - 2008 Unique secretory dynamics of tissue plasminogen activator and vascular function
- 2006 - 2007 Real time imaging analysis of platelets aggregation and thrombus formation under shear stress
- 2001 - 2002 Real time imaging analysis of molecular interactions of factors involved in fibrinolysis on cell surface to modify cell migration
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Papers (65)：
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Christopher D. Barrett, Yuko Suzuki, Ernest E. Moore, Hunter B. Moore, Elizabeth R. Maginot, Collin M. White, Halima Siddiqui, Flobater I. Gawargi, James G. Chandler, Angela Sauaia, et al. A Novel Fibrinolysis Resistance Capacity Assay Can Detect Fibrinolytic Phenotypes in Trauma Patients. Thrombosis and Haemostasis. 2025
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Kyota Tatsuta, Naoki Honkura, Nanami Morooka, Mayu Sakata, Kiyotaka Kurachi, Ken Sugimoto, Koichi Kokame, Hiroya Takeuchi, Tetsumei Urano, Yuko Suzuki. Microthrombi-growth in ADAMTS13 deficiency exacerbated ulcerative colitis via mucosal and endothelial dysfunction. 2024
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Yuko Suzuki, Nitty Mathews, Hideto Sano, Nanami Morooka, Naoki Honkura, Tetsumei Urano. Real-time imaging of platelet-initiated plasma clot formation and lysis unveils distinct impacts of anticoagulants. Thrombosis and Haemostasis. 2024. accepted
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Chris Ward, Nicola Curry, Magdy El-Ekiaby, Kerstin Jurk, Henri H Versteeg, Charithani Keragala, Tal Burstyn-Cohen, Silvio Antoniak, Yuko Suzuki, Ross I Baker, et al. Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress. Research and practice in thrombosis and haemostasis. 2024. 8. 4. 102432-102432
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Tetsumei Urano, Yoshie Sano, Yuji Suzuki, Masahiko Okada, Hideto Sano, Naoki Honkura, Nanami Morooka, Matsuyuki Doi, Yuko Suzuki. Evaluation of thrombomodulin/thrombin activatable fibrinolysis inhibitor function in plasma using tissue-type plasminogen activator-induced plasma clot lysis time. Research and Practice in Thrombosis and Haemostasis. 2024. 8. 4. 102463-102463
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MISC (145)：
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鈴木 優子. 日常臨床で診断のつかない出血傾向への対応 線溶制御不全による出血症の診断. 日本検査血液学会雑誌. 2024. 25. 学術集会. S97-S97
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鈴木 優子. 「出血性線溶異常症」 線溶制御不全による出血病態を理解する. 日本血栓止血学会誌. 2024. 35. 2. 134-134
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安井 秀樹, 大石 享平, 井上 裕介, 鈴木 勇三, 穗積 宏尚, 柄山 正人, 古橋 一樹, 藤澤 朋幸, 榎本 紀之, 堀之内 孝広, et al. 慢性閉塞性肺疾患(COPD)の疾患進行に及ぼす動脈硬化の影響. 日本血栓止血学会誌. 2024. 35. 2. 264-264
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浦野 哲盟, 鈴木 優子. 線溶抵抗活性の新規迅速測定法. 日本血栓止血学会誌. 2024. 35. 2. 314-314
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浦野哲盟, 浦野哲盟, 鈴木優子. Thrombogenicity caused by elevated circulating PAI-1. 日本臨床. 2024
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Patents (1)：
Lectures and oral presentations (25)：
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Imaging analysis of spatiotemporally regulated crosstalk between thrombus formation and its lysis
(The 97th Annual Meeting of the Physiological Society of Japan 2020)
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Modulation of thrombin generation or thrombin activity on activated platelets surface largely affected TAFI-dependent regulation of fibrinolysis
(The XXVII Congress of the International Society on Thrombosis and Hemostasis (ISTH) 2020)
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Spatiotemporal regulation of thrombin-activatable fibrinolysis inhibitor (TAFI) activation on activated platelets.
(Gordon Research Conference(GRC)- Plasminogen Activation and Extracellular Proteolysis 2020)
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「次世代リーダーからのメッセージ」血栓形成-溶解機構の時空間的解析
(第 42 回日本血栓止血学会学術集会 2020)
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血栓形成溶解の時空間的制御
(第82回日本血液学会学術集会 2020)
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Education (1)：
- 1987 - 1993 Hamamatsu University School of Medicine Faculty of Medicine School of Medicine
Professional career (1)：
Awards (4)：
- 2021/05 - 日本血栓止血学会 岡本Utako Award
- 2019/06 - 第41回日本血栓止血学会学術集会 一般演題優秀賞
- 2009 - 浜松医科大学同窓会 学術奨励賞
- 2009 - 日本血栓止血学会 2011 ISTH Memorial Award
Association Membership(s) (9)：
日本血管生物医学会
, 日本内分泌学会
, 日本血液学会
, 日本糖尿病学会
, 日本内科学会
, 日本血栓止血学会
, 日本生理学会
, 国際線溶学会
, ISTH
