Research field (3):
Molecular biology
, Pharmaceuticals - analytical and physicochemistry
, Pharmaceuticals - health and biochemistry
Research keywords (2):
生体分子
, bio-molecules
Research theme for competitive and other funds (19):
2021 - 2024 Development of nobel assay methods for miRNA and adenine methyltransferase using FRET
2017 - 2020 Development of the novel assay method for chromatin modified enzymes and application to epigenetics analysis
2014 - 2017 Development of the anti-AIDS drug using aptamer-siRNA
2010 - 2014 Development of the nucleic acid aptamer for anti HIV drug
2011 - 2013 Development of the discrimination method for mutation and drug resistance of an AIDS virus
2007 - 2010 Development of a novel detection method for abnormal prion protein
2007 - プリオンタンパク質に関する研究
2007 - ウイルスプロテアーゼに関する研究
2007 - Study on prion protein
2007 - Study on virus protease
2005 - 2006 糖質応答領域結合タンパク質による糖質および脂質代謝調節機構の解明
2002 - 2006 Development of Super-Sensitive Technique for the Detection of Nucleic Acids with Luminescent Reagent
2004 - 2004 新規高分子発光プローブによる発現遺伝子の超高感度マイクロアレー解析
2003 - 2004 糖質応答領域結合タンパクの調節機構の解明
2003 - 2003 新規高分子発光プローブによるmRNAのマイクロアレー解析
2000 - 2002 Structure analysis of proline specific peptidases which have unique specificity and structure
2002 - 転写調節に関する研究
2002 - Study on transcriptional regulation
1996 - 1996 プロリン特異性ペプチダーゼの構造とプロリン特異性発現機構の解明
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Papers (25):
Makoto Takada, Ichika Watanabe, Kazuya Naito, Junpei Mutoh, Yoshihito Ohba, Tsutomu Kabashima, Mitsuhiro Wada. Extremely Simple and Rapid HPLC Analysis of Tocilizumab in Human Serum with Selective Precipitation Using Alkylamine. Chemical and Pharmaceutical Bulletin. 2023. 71. 1. 19-23
Takayuki Shibata, Ryosuke Shimamura, Yuji Yamamoto, Hiroki Sakurai, Junya Fujita, Asako Yamayoshi, Toshimitsu Nemoto, Tsutomu Kabashima. A Facile Method for the Quantification of Urinary Uracil Concentration by a Uracil-Specific Fluorescence Derivatization Reaction. Chemical & pharmaceutical bulletin. 2021. 69. 8. 768-772
Tsutomu Kabashima, Keiko Tonooka, Makoto Takada, Masaaki Kai, Takayuki Shibata. Simultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection. Scientific reports. 2019. 9. 1. 9150-9150