Kimura Tetsunari

キムラテツナリ | Kimura Tetsunari

Affiliation and department：
Job title： Associate Professor

Research field (3)： Biophysics , Biochemistry , Basic physical chemistry

Research keywords (1)：蛋白質のダイナミクス

Research theme for competitive and other funds (13)：

2023 - 2027 Development of Single-Molecule Reaction Imaging Techniques for Visualizing Carbon Resource Transformation
2022 - 2025 Time-resolved measurements of allocrite transport in ABC transporters
2021 - 2024 病原菌ヘムトランスポーターの構造変化の追跡と基質輸送機構の解明
2019 - 2024 時間分解構造解析を補完する精密顕微分光計測
2017 - 2019 タンパク質ダイナミクス観測に資する高時空間分解能ESR・IR計測系の開発と応用

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Papers (65)：

Hongjie Li, Yoshiki Nakajima, Eriko Nango, Shigeki Owada, Daichi Yamada, Kana Hashimoto, Fangjia Luo, Rie Tanaka, Fusamichi Akita, Koji Kato, et al. Oxygen-evolving photosystem II structures during S1-S2-S3 transitions. Nature. 2024. 626. 7999. 670-677
Hanae Takeda, Kanji Shimba, Masaki Horitani, Tetsunari Kimura, Takashi Nomura, Minoru Kubo, Yoshitsugu Shiro, Takehiko Tosha. Trapping of a Mononitrosyl Nonheme Intermediate of Nitric Oxide Reductase by Cryo-Photolysis of Caged Nitric Oxide. The journal of physical chemistry. B. 2023. 127. 4. 846-854
Takashi Nomura, Tetsunari Kimura, Yusuke Kanematsu, Daichi Yamada, Keitaro Yamashita, Kunio Hirata, Go Ueno, Hironori Murakami, Tamao Hisano, Raika Yamagiwa, et al. Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography. Proceedings of the National Academy of Sciences. 2021. 118. 21. e2101481118-e2101481118
Hongjie Li, Yoshiki Nakajima, Takashi Nomura, Michihiro Sugahara, Shinichiro Yonekura, Siu Kit Chan, Takanori Nakane, Takahiro Yamane, Yasufumi Umena, Mamoru Suzuki, et al. Capturing structural changes of the S1 to S2 transition of photosystem II using time-resolved serial femtosecond crystallography. IUCrJ. 2021. 8. Pt 3. 431-443
Kazumasa Oda, Takashi Nomura, Takanori Nakane, Keitaro Yamashita, Keiichi Inoue, Shota Ito, Johannes Vierock, Kunio Hirata, Andrés D Maturana, Kota Katayama, et al. Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin. eLife. 2021. 10

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MISC (12)：

北野さくら, 柚佳祐, 笹田航, 木村哲就, 茶谷絵理. ドデシル硫酸ナトリウム共存下でのαシヌクレイン凝集反応の多様性. 日本蛋白質科学会年会プログラム・要旨集. 2023. 23rd (CD-ROM)
阪口智哉, 澤井仁美, 城宜嗣, 鍔木基成, 當舎武彦, 木村哲就, 杉本宏. 鉄還元機能を持つ6回膜貫通型タンパク質101F6の大腸菌での発現と機能解析. 日本生化学会大会(Web). 2023. 96th
南後恵理子, 南後恵理子, LUO Fangjia, LUO Fangjia, 木村哲就, 菅原道泰, 中根崇智, 鈴木守, 桝田哲哉, 溝端栄一, et al. 二液混合シリアルフェムト秒結晶構造解析による酵素反応追跡. 日本結晶学会年会講演要旨集. 2021. 2021
Tetsunari Kimura, Hanae Takeda, Shoko Ishii, Takehiko Tosha, Yoshitsugu Shiro, Minoru Kubo. Molecular Mechanism of the Catalytic Reaction of no Reductase Revealed by Novel Time-Resolved Visible/IR Absorption Spectrometers with Microfluidic Device. BIOPHYSICAL JOURNAL. 2016. 110. 3. 548A-548A
田中智之, 菅原道泰, 中根崇智, 木村哲就, 木村哲就, 久保稔, 久保稔, 宮島謙, 宮島謙, 登野健介, et al. SACLAにおけるシリアルフェムト秒X線結晶構造解析の技術開発. 日本結晶学会年会講演要旨集. 2016. 2016

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Books (1)：

ヘムタンパク質の科学 : 生理機能の理解とその展開に向けて
エヌ・ティー・エス 2022 ISBN:9784860437787

Lectures and oral presentations (103)：

Spectroscopic analysis of BhuUV-T reconstituted with amphiphilic polymers
(The 61st Annual Meeting of the Biophysical Society of Japa 2023)
Thermodynamic and kinetic analyses of interaction between aequorin and Ca2+
(2023)
Investigation of the mechanism of heme transport in the ABC transporter BhuUV-T by spectroscopic methods
(2023)
鉄還元機能を持つ6回膜貫通型タンパク質101F6の大腸菌での発現と機能解析
(第96回日本生化学会大会 2023)
Development of microfluidic mixers for time-resolved SFX and spectroscopy and their applications
(UK/Japan meeting and workshop “Dynamic Crystallography-XFELs and Synchrotrons to study enzyme reactions” 2023)

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Education (3)：

- 2005 京都大学大学院工学研究科博士後期課程分子工学専攻修了
- 2002 Kyoto University
- 2000 Kyoto University Faculty of Engineering School of Industrial Chemistry

Professional career (2)：

修士(工学) (京都大学)
博士(工学) (京都大学)

Work history (1)：

Kyoto University Graduate School of Engineering, Department of Molecular Engineering

Awards (2)：

2018/10 - International Congress on Pure and Applied Chemistry Langkawi 2018 Plenary Lecture Award(International Congress on Pure and Applied Chemistry Langkawi 2018) Membrane proteins in action; Structural and functional dynamics revealed by time-resolved measurements.
2015/06 - Protein Science Society of Japan 蛋白質科学会若手奨励賞マイクロ流体フローを用いた一酸化窒素還元酵素の触媒反応の動的分光観察

Association Membership(s) (4)：

Protein Science Society of Japan , 生物物理学会(Biophysical Society, U.S.A.) , 日本生物物理学会 , 日本化学会

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