Research theme for competitive and other funds (12)：
2022 - 2025 レセプター依存的マイトファジーの誘導制御と生理機能の解明
2022 - 2025 Elucidation of the molecular mechanism of the mitophagy contributing to the drug resistance and its application to chemotherapy
2017 - 2020 Morphological analysis of mitochondria during mitophagy
2018 - 2019 Molecular mechanisms and physiological role of mitochondria DNA in mitochondria-related disease
2017 - 2019 Molecular mechanisms and physiological role of degradation of mitochondria DNA by autophagy
2015 - 2018 Molecular mechanisms and physiological role of hypoxia-induced mitochondria degradation
2014 - 2017 Molecular mechanism of mitochondrial autophagy
2015 - 2017 Morphological analysis of mitochondria during mitophagy
2013 - 2015 Screen the chemicals that efficiently induce mitophagy
2010 - 2013 Molecular mechanisms and physiological role of peroxisome degradation in mammalian cells
2010 - 2012 Novel degradation pathway of peroxisomes in mammalian cells
2003 - 2007 Elucidation of intracellular membrane synthesis during pexophagy
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Papers (42)：
Tamara Ginevskaia, Aleksei Innokentev, Kentaro Furukawa, Tomoyuki Fukuda, Manabu Hayatsu, Shun-ichi Yamashita, Keiichi Inoue, Shinsuke Shibata, Tomotake Kanki. Comprehensive analysis of non-selective and selective autophagy in yeast atg mutants and characterization of autophagic activity in the absence of the Atg8 conjugation system. The Journal of Biochemistry. 2024
Shun-Ichi Yamashita, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Keiichi Inoue, Kentaro Furukawa, Tomoyuki Fukuda, David C Chan, Tomotake Kanki. Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species. Cell death and differentiation. 2024
Kyota Aoyagi, Chiyono Nishiwaki, Yoko Nakamichi, Shun-ichi Yamashita, Tomotake Kanki, Mica Ohara-Imaizumi. Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic β-cells from db/db mice. Scientific Reports. 2024. 14. 1
Fukuda T, Saigusa T, Furukawa K, Inoue K, Yamashita SI, Kanki T. Hva22, a REEP family protein in fission yeast, promotes reticulophagy in collaboration with a receptor protein. Autophagy. 2023
2003 - 2007 Kyoto University Graduate School of Agriculture Division of Applied Life Sciences
2001 - 2003 Tokyo University of Agriculture Fuculty of Applied Bioscience Department of Applied Biology and Chemistry
1997 - 2001 Tokyo University of Agriculture Fuculty of Applied Bioscience Department of Applied Biology and Chemistry
Professional career (1)：
Master(Agriculture Chemistry) (Tokyo University of Agriculture)
Work history (9)：
2024/04 - 現在 Kyushu University Graduate School of Medical Sciences
2024/04 - 現在 Niigata University Graduate School of Medical and Dental Sciences
2016/07 - 2024/03 Niigata University Department of Cellular Physiology, Niigata University Graduate School of Medical and Dental Sciences Assistant Professor
2018/10 - 2019/10 California Institute of Technology Division of Biology and Biological Engineering Visiting Associate
2014/01 - 2016/06 Niigata University Department of Cellular Physiology, Niigata University Graduate School of Medical and Dental Sciences Research Assistant Professor
2013/04 - 2013/12 Kyushu University Department of Biology, Faculty of Sciences Postdoctoral reseacher
2010/04 - 2013/03 Kyushu University Department of Biology, Faculty of Sciences Research Fellow of the Japan Society for the Promotion of Science
2008/05 - 2010/03 Kyushu University Department of Biology, Faculty of Sciences Postdoctral researcher
2007/07 - 2008/04 Kyoto University Division of Applied Life Sciences, Graduate School of Agriculture Postdoctoral researcher
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Awards (3)：
2017/09 - Niigata University President's Award Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy
2013 - The Japanese Biochemical Society 鈴木紘一メモリアル賞 Induction of peroxisome degradation by overloading of peroxisome membrane protein in mammalian cells
2011 - The Japanese Biochemical Society Samuro Kakiuchi Memorial Research Award for Young Scientists Quality control of peroxisome membrane proteins
Association Membership(s) (4)：
The Molecular Biology Society of Japan
, JAPAN SOCIETY FOR CELL BIOLOGY
, THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE
, THE JAPANESE BIOCHEMICAL SOCIETY
