Sakurai Toshihiro

サクライトシヒロ | Sakurai Toshihiro

Affiliation and department：

Research field (1)： Animal production science

Research keywords (4)： Placentology , Breeding Science , Female reproductive tract , Endocrinology

Research theme for competitive and other funds (8)：

2022 - 2025 Analysis of differentiation mechanism of bovine trophoblast cells into placental component cells.
2019 - 2022 ウシの妊娠における着床成立時の子宮内環境の解明
2016 - 2020 Establishment and re-establishment of uterine environment for pregnancy success
2016 - 2019 Role of autophagy dysfunction in environmental electrophile-induced cognitive disorder
2015 - 2018 妊娠率向上を目指したウシ内在性レトロウイルスの機能解析

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Papers (79)：

Toshihiro Sakurai, Kazuya Kusama, Kazuhiko Imakawa. Progressive Exaptation of Endogenous Retroviruses in Placental Evolution in Cattle. Biomolecules. 2023. 13. 12
Rulan Bai, Kazuya Kusama, Yuta Matsuno, Hanako Bai, Toshihiro Sakurai, Koji Kimura, Kazuhiko Imakawa. Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period. Frontiers in endocrinology. 2023. 14. 1075030-1075030
Kazuya Kusama, Rulan Bai, Yuta Matsuno, Atsushi Ideta, Toshihiro Sakurai, Kentaro Nagaoka, Masatoshi Hori, Kazuhiko Imakawa. Characterization of Serum Metabolome and Proteome Profiles Identifies SNX5 Specific for Pregnancy Failure in Holstein Heifers. Life. 2022. 12. 2. 309-309
Ryoya Takizawa, Sahoko Ichihara, Cai Zong, Kazuo Kinoshita, Toshihiro Sakurai, Akihiko Ikegami, Nathan Mise, Gaku Ichihara. 1,2-Dichloropropane induces γ-H2AX expression in human cholangiocytes only in the presence of macrophages. Toxicology letters. 2021. 349. 134-144
Hirona Murata, Hiroki Kunii, Kazuya Kusama, Toshihiro Sakurai, Hanako Bai, Manabu Kawahara, Masashi Takahashi. Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells. Biology of Reproduction. 2021. 105. 5. 1114-1125

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MISC (153)：

櫻井敏博. Effects of taking herbal medicines in early gestation on pregnancy and placental formation. 日本薬学会年会要旨集(Web). 2024. 144th
YAMAZAKI Kyoka, VRANIC Sandra, WATANABE Eri, MIYAKAWA Kayoko, TAKEUCHI Sakie, OSADA Yurika, ICHIHARA Sahoko, WU Wenting, ZONG Cai, SAKURAI Toshihiro, et al. Mechanism of macrophage injury by amorphous silica nanoparticles. Annual Meeting of the Japanese Society of Toxicology. 2023. 50.1. Supplement (CD-ROM). P1-067S
須釜萌衣, 阿部惇平, 櫻井敏博. ケイヒ酸はp38のリン酸化を抑制することで血管内皮細胞のVEGFによる管腔形成を阻害する. 日本薬学会東北支部大会講演要旨集. 2022. 61st
櫻井敏博. 胎盤の形態を決める進化の伴走者 : 胎盤と内在性レトロウイルス. 福島の進路. 2022. 473. 60-63
櫻井敏博, 阿部惇平, 深谷莉菜. 桂皮熱水抽出物曝露による不死化ヒト初期絨毛株HTR8細胞の増殖抑制. 日本絨毛性疾患研究会・日本胎盤学会学術集会プログラム・抄録集. 2021. 39th-29th

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Books (1)：

Diabetes Frontier
メディカルレビュー社 2006

Lectures and oral presentations (2)：

Establishment of in vitro assessment system for conceptus attachment to the uterine epithelial cells
(2011)
Epigenetic regulation of gene expression in the bovine trophoblast
(2011)

Education (1)：

- 2006 Tokyo University of Pharmacy and Life Science Pharmaceutical Sciences

Professional career (1)：

Ph.D. (Tokyo University of Pharmacy and Life Science)

Work history (5)：

2019/04 - 現在 Ohu University The School of Pharmaceutical Science Associate professor
2014/04 - 2019/03 Tokyo University of Science Faculty of Phamaceutical Sciences Assistant Professor
2013/04 - 2014/03 Yokohama University of Pharmacy Faculty of Phamacy Lecturer
2006/08 - 2013/03 University of Tokyo Graduate School of Agricultural and Life Sciences Research Assistant Professor
2006/04 - 2006/07 Tokai University Postdoctoral fellow

Association Membership(s) (5)：

Society for the study of reproduction , JAPANESE SOCIETY OF ANIMAL SCIENCE , THE JAPANESE SOCIETY FOR HYGIENE , THE PHARMACEUTICAL SOCIETY OF JAPAN , SOCIETY FOR REPRODUCTION AND DEVELOPMENT

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