Rchr
J-GLOBAL ID:200901015588194642   Update date: Jun. 25, 2024

Doh-ura Katsumi

ドウウラ カツミ | Doh-ura Katsumi
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://www.neurochemistry.med.tohoku.ac.jp
Research field  (1): Neurology
Research keywords  (5): プリオン ,  治療開発 ,  タンパク質コンフォメーション病 ,  ケミカルバイオロジー ,  神経化学
Research theme for competitive and other funds  (17):
  • 2022 - 2025 セルロースエーテルが関わるプリオンに対する生体防御機構の解明
  • 2021 - 2023 異常蛋白質の排除機構に関する新原理の探究
  • 2019 - 2022 Identification of cellulose ether susceptibility genes involved in suppression of prion disease development
  • 2017 - 2020 Study for bringing a new dimension in the pathogenesis of prion disease.
  • 2016 - 2019 Analysis of host genetic factors associated with disease suppression against prion diseases.
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Papers (126):
  • Kenta Teruya, Ayumi Oguma, Sara Iwabuchi, Keiko Nishizawa, Katsumi Doh-ura. Improvement of anti-prion efficacy with stearoxy conjugation of hydroxypropyl methylcellulose in prion-infected mice. Carbohydrate Polymers. 2024. 337
  • Kenta Teruya, Ayumi Oguma, Sara Iwabuchi, Keiko Nishizawa, Katsumi Doh-ura. Combination of Styrylbenzoazole Compound and Hydroxypropyl Methylcellulose Enhances Therapeutic Effect in Prion-Infected Mice. Molecular Neurobiology. 2023
  • Kenta Teruya, Ayumi Oguma, Satoko Takahashi, Miki Watanabe-Matsui, Sachiyo Tsuji-Kawahara, Masaaki Miyazawa, Katsumi Doh-ura. Anti-prion activity of cellulose ether is impaired in mice lacking pre T-cell antigen receptor α, T-cell receptor δ, or lytic granule function. International Immunopharmacology. 2022. 107. 108672-108672
  • Kenta Teruya, Katsumi Doh-Ura. Therapeutic development of polymers for prion disease. Cell and tissue research. 2022. Online ahead of print. 1. 349-365
  • Kenta Teruya, Sara Iwabuchi, Yuki Watanabe, Rikiya Tsuchida, Miki Watanabe-Matsui, Hiroyuki Konno, Katsumi Doh-ura. Activities of curcumin-related compounds in two cell lines persistently infected with different prion strains. Biochimica et biophysica acta. General subjects. 2022. 1866. 4. 130094-130094
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MISC (139):
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Patents (2):
  • コンフォメーション病医薬組成物
  • 異常型プリオン蛋白質の濃縮方法、および除去方法
Books (2):
  • Prions - Food and Drug Safety
    Springer 2005
  • 脳科学研究の現状と課題
    じほう社 2003
Lectures and oral presentations  (134):
  • Our Quest for Anti-prion Compounds 2022.
    (Asian Pacific Prion Symposium 2022.)
  • Structure-Activity relationship of curcumin-related compounds in ScN2a and N167.
    (Asian Pacific Prion Symposium 2022.)
  • Characterization of the actions of CRANAD on two prion strains and PrP-amyloid.
    (第59回ペプチド討論会)
  • フェロトーシス阻害剤による異常型プリオンタンパク質蓄積抑制機構の解明
    (第44回日本分子生物学会年会)
  • Photoreaction-induced SDS-resistant PrPSc/res oligomer formation.
more...
Professional career (1):
  • 医学博士
Committee career (4):
  • 2011/07 - 現在 Asian Pacific Society of Prion Research 理事
  • 2014/04 - 2018/03 食品安全委員会 プリオン専門調査会 専門委員
  • 2015/09 - 2017/10 Asian Pacific Society of Prion Research 理事長
  • 2005/01 - 2013/01 生物由来製品感染等被害判定調査会 薬事・食品衛生審議会専門委員
Association Membership(s) (1):
Asian Pacific Society of Prion Research
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