Rchr
J-GLOBAL ID：200901015740366373
Update date: Sep. 19, 2024
Yahata Kazuhide
ヤハタ カズヒデ | Yahata Kazuhide
Affiliation and department：
Job title：
Associate Professor
Homepage URL (1)：
https://www.m.ehime-u.ac.jp/school/parasitology/
Research field (1)：
Parasitology
Research keywords (5)：
赤血球侵入
, 遺伝子制御
, イメージング
, マラリア
, Malaria imaging gene regulation
Research theme for competitive and other funds (20)：
- 2022 - 2025 Molecular mechanisms of gliding motility in blood-stage malaria parasites
- 2019 - 2022 Signaling mechanism of the apical organelle discharge by malaria parasites during erythrocyte invasion
- 2019 - 2022 Molecular mechanisms of gliding motility and erythrocyte invasion by Plasmodium falciparum
- 2019 - 2021 マラリア原虫の赤血球侵入期における滑走運動の役割
- 2016 - 2019 Signaling in malaria parasites during erythrocyte invasion
- 2017 - 2018 赤血球侵入型マラリア原虫の滑走運動と赤血球侵入機構
- 2015 - 2018 マラリア原虫における赤血球密着接合分子の機能解析
- 2015 - 2017 マラリア原虫のカルシウム調節機構の解明と阻害剤評価法の開発
- 2013 - 2016 Epidemiological and experimental studies of Tick-borne viruses in Indochina
- 2013 - 2016 Signal transduction during erythrocyte invasion by malaria parasites
- 2012 - 2016 Seroepidemiology of the molecules expressed on the Plasmodium vivax-infected erythrocyte surface
- 2011 - 2016 Matryoshka-type cell configuration by organelles evolved for the parasitism
- 2012 - 2015 Ultrastructural analysis of Maurer's clefts of Plasmodium falciparum infected red blood cell
- 2012 - 2015 マラリア原虫の赤血球侵入関連分子の時間? 空間的動態解析
- 2011 - 2012 Genetic manipulation to generate transgenic Plasmodium vivax invasive to the mature erythrocytes
- 2010 - 2012 Identification and targeting of the functional domains of malaria parasite's molecules involved in the erythrocyte invasion
- 2010 - 2012 遺伝子間隙壁に着目したマラリア原虫の遺伝子発現メカニズムの解明
- 2008 - 2010 マラリア原虫の転写干渉機構とその制御
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Papers (50)：
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Nattawat Chaiyawong, Takahiro Ishizaki, Hassan Hakimi, Masahito Asada, Kazuhide Yahata, Osamu Kaneko. Distinct effects on the secretion of MTRAP and AMA1 in Plasmodium yoelii following deletion of acylated pleckstrin homology domain-containing protein. Parasitology International. 2022. 102479-102479
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Kazuhide Yahata, Melissa N Hart, Heledd Davies, Masahito Asada, Samuel C Wassmer, Thomas J Templeton, Moritz Treeck, Robert W Moon, Osamu Kaneko. Gliding motility of Plasmodium merozoites. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 48
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Takahiro Ishizaki, Masahito Asada, Hassan Hakimi, Nattawat Chaiyawong, Yuto Kegawa, Kazuhide Yahata, Osamu Kaneko. cAMP-dependent protein kinase regulates secretion of apical membrane antigen 1 (AMA1) in Plasmodium yoelii. Parasitology International. 2021. 102435-102435
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Shinya Miyazaki, Ben-Yeddy Abel Chitama, Wataru Kagaya, Amuza Byaruhanga Lucky, Xiaotong Zhu, Kazuhide Yahata, Masayuki Morita, Eizo Takashima, Takafumi Tsuboi, Osamu Kaneko. Plasmodium falciparum SURFIN4.1 forms an intermediate complex with PTEX components and Pf113 during export to the red blood cell. Parasitology international. 2021. 83. 102358-102358
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Melanny Ika Sulistyowaty, Nguyen Hoang Uyen, Keisuke Suganuma, Ben-Yeddy Abel Chitama, Kazuhide Yahata, Osamu Kaneko, Sachiko Sugimoto, Yoshi Yamano, Susumu Kawakami, Hideaki Otsuka, et al. Six New Phenylpropanoid Derivatives from Chemically Converted Extract of Alpinia galanga (L.) and Their Antiparasitic Activities. Molecules (Basel, Switzerland). 2021. 26. 6
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MISC (43)：
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CHITAMA Ben Yeddy Abel, MIYAZAKI Shinya, ZHU Xiaotong, KAGAYA Wataru, YAHATA Kazuhide, KANEKO Osamu. Characterization of the Plasmodium falciparum SURFIN4.1 N-terminal region for transport to the Maurers clefts of infected erythrocytes. 日本寄生虫学会大会プログラム・抄録集. 2019. 88th
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矢幡一英. マラリア原虫の赤血球侵入と放出の分子メカニズム. 細胞(ニュー・サイエンス社). 2017. 49. 17
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石川岳志, 水田賢志, 金子修, 矢幡一英. 抗マラリア化合物の開発をめざしたフラグメント分子軌道法によるSERCAとThapsigarginの分子間相互作用解析. 日本薬学会年会要旨集(CD-ROM). 2017. 137th
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矢幡一英, 外川裕人, 金子修. マラリアの現状:薬剤耐性とワクチン開発. 臨床と研究. 2016. 93. 12. 1571-1575
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矢幡一英, 外川裕人, 金子修. マラリアの現状:薬剤耐性とワクチン開発. 臨床と研究 (大道学館). 2016. 93. 12. 27-31
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Patents (1)：
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不死化赤血球前駆細胞由来の血球様細胞を用いたマラリア原虫等の維持培養・感染評価に適した細胞の決定
Books (1)：
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Cell engineering using integrate and recombinase systems.
Emerging Technology Platforms For Stem Cells 2009
Lectures and oral presentations (75)：
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Gliding motility and erythrocyte invasion of Plasmodium merozoites
(U.S.-Japan Cooperative Medical Sciences Program (USJCMSP) U.S -Japan Parasitic Diseases Joint Panel Meeting 2024)
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Unveiling Gliding Motility in Plasmodium Merozoites
(Molecular Approaches to Malaria 2024 2024)
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Unveiling Gliding Motility in Plasmodium Merozoites : Insights from Live-Cell Imaging
(Protein Island Matsuyama 2023 International Symposium 2023)
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マラリア原虫の赤血球侵入と滑走運動
(第29回 分子寄生虫学ワークショップ 2023)
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マラリア原虫の宿主細胞侵入メカニズム
(第75回 日本細胞生物学会大会 2023)
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Education (3)：
- - 2007 大阪大学大学院 薬学研究科 応用医療薬科学専攻博士課程修了
- - 2001 Hiroshima University Graduate School of Science
- - 1999 Tottori University Faculty of Agriculture
Professional career (1)：
- Doctor(Pharmacology) (Osaka University)
Work history (7)：
Awards (2)：
- 2022/03 - Alumni Association of Institute of Tropical Medicine, Nagasaki University Present Award of Alumni Association of Institute of Tropical Medicine, Nagasaki University Gliding motility of Plasmodium merozoites
- 2015 - プロテイン・アイランド松山国際シンポジウム2015 若手ベストプレゼンテーション賞
Association Membership(s) (3)：
日本寄生虫学会
, 日本分子生物学会
, Molecular Biology Society Of Japan
