Rchr
J-GLOBAL ID:200901015795091071   Update date: Oct. 25, 2024

Murohara Toyoaki

Murohara Toyoaki
Affiliation and department:
Job title: Professor
Research field  (1): Cardiology
Research keywords  (11): 代謝異常と循環器疾患 ,  Renin-Angiotensin System ,  Hyperlipidemia ,  Hypertension ,  Cardiovascular Medicine ,  Bone marrow stem cell ,  Endothelial cell ,  Regenerative Medicine ,  Therapeutic Angiogenesis ,  Vascular Regenerarion ,  Vascular Biology
Research theme for competitive and other funds  (70):
  • 2022 - 2025 脂肪組織由来間葉系前駆細胞を用いたリンパ浮腫に対するリンパ管新生療法の開発研究
  • 2022 - 2025 肺細動脈内皮細胞で特徴的変化を示す分子に着目した肺高血圧症への新規治療戦略の開発
  • 2021 - 2024 新規抗炎症性アディポカインによる心臓病、腎臓病制御機構の解明
  • 2021 - 2024 劇症型心筋炎における急性期管理法の確立および低侵襲早期診断マーカーの探索と開発
  • 2021 - 2024 ホルモン連関とクローン性造血から探る糖尿病性心筋症の原因解析
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Papers (1,070):
  • Satoya Yoshida, Tatsuya Yoshida, Kohei Inukai, Katsuhiro Kato, Yoshimitsu Yura, Tomoki Hattori, Atsushi Enomoto, Koji Ohashi, Takahiro Okumura, Noriyuki Ouchi, et al. Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion. Nature communications. 2024. 15. 1. 7638-7638
  • Tomoya Iwawaki, Yasuya Inden, Satoshi Yanagisawa, Takayuki Goto, Shun Kondo, Masaya Tachi, Kei Hiramatsu, Ryota Yamauchi, Masafumi Shimojo, Yukiomi Tsuji, et al. A Novel Liver Fibrosis Marker FIB-5 Index Predicted Response to Cardiac Resynchronization Therapy and Prognostic Outcomes in Patients With Heart Failure. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc. 2024. 29. 5. e70004
  • Yusuke Fujikawa, Katsuhiro Kato, Kazumasa Unno, Shingo Narita, Yusuke Okuno, Yoshitaka Sato, Mikito Takefuji, Toyoaki Murohara. Dynamic upregulation of retinoic acid signal in the early postnatal murine heart promotes cardiomyocyte cell cycle exit and maturation. Scientific reports. 2024. 14. 1. 20222-20222
  • Toshikazu Ishihara, Katsuhiro Kato, Kotaro Matsumoto, Miyako Tanaka, Akitoshi Hara, Yukihiro Shiraki, Hidenori Morisaki, Yuya Urano, Ryota Ando, Kisuke Ito, et al. Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis. Genes to cells : devoted to molecular & cellular mechanisms. 2024
  • Ryo Watanabe, Hiroyuki Kato, Satoshi Yanagisawa, Taku Sakurai, Ryusuke Ota, Hisashi Murakami, Kenji Kada, Naoya Tsuboi, Yasuya Inden, Rei Shibata, et al. Long-Term Outcomes in Patients With Relatively High His-Bundle Capture Threshold After Permanent His-Bundle Pacing - A Multicenter Clinical Study. Circulation reports. 2024. 6. 8. 294-302
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MISC (1,149):
  • 中野 嘉久, 足立 史郎, 廣瀬 未来, 安達 健, 西山 軼群, 安田 健一郎, 吉田 雅博, 岩野 信吾, 八谷 寛, 近藤 隆久, et al. Refined CTプロトコールによる急性肺塞栓症1年後の残存血栓の検出. 日本肺高血圧・肺循環学会学術集会・日本小児肺循環研究会プログラム・抄録集. 2022. 7回・28回. 126-126
  • 西山 軼群, 足立 史郎, 安田 健一郎, 吉田 雅博, 中野 嘉久, 近藤 隆久, 室原 豊明. 肺動脈血栓内膜摘除術数年後に収縮性心内膜炎を発症した一例. 日本肺高血圧・肺循環学会学術集会・日本小児肺循環研究会プログラム・抄録集. 2022. 7回・28回. 139-139
  • 小林聖典, 六鹿雅登, 六鹿雅登, 奥村貴裕, 奥村貴裕, 平岩宏章, 平岩宏章, 近藤徹, 近藤徹, 室原豊明, et al. 高齢植込み型補助人工心臓装着患者の運動機能に関する検討. 人工臓器(日本人工臓器学会). 2020. 49. 2
  • 小林聖典, 奥村貴裕, 奥村貴裕, 平岩宏章, 平岩宏章, 近藤徹, 近藤徹, 六鹿雅登, 六鹿雅登, 藤本和朗, et al. LVAD装着術後患者の退院時下肢筋力は再入院と関連する. 日本心不全学会学術集会プログラム・抄録集. 2020. 24th (CD-ROM)
  • 大石英生, 奥村貴裕, 清水美帆, 竹内晴美, 荒尾嘉人, 加藤宏雄, 桑山輔, 羽賀智明, 山口尚悟, 横井剛, et al. Exercise and Nutritional Intervention in the Acute Phase of Cardiac/Intensive Care in Patients with Advanced Heart Failure. 日本循環器学会学術集会(Web). 2019. 83rd
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Patents (1):
  • Therapeutic angiogenesis by bone marrow-derived cell transplantation in myocardial ischemic tissue and skeletal muscle ischemic tissue.
Professional career (2):
  • 医学博士 (熊本大学)
  • Medical Doctor (Kumamoto University)
Work history (12):
  • 2004/10/01 - 現在 Nagoya University Program in Integrated Molecular Medicine Professor
  • 2002/06/01 - Department of Cardiology, Nagoya University Graduate School of Medicine
  • 1997/07/01 - 2002/05/31 Department of Internal Medicine III, Kurume University School of Medicine
  • 1996/03/01 - 1997/06/30 Department of Cardiology, St. Elizabeth's Medical Center, Tufts University School of Medicine
  • 1993/09/01 - 1996/02/28 Department of Physiology, Jefferson Medical School of Thomas Jefferson University
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Association Membership(s) (8):
European Society of Cardiology ,  日本血管生物医学会 ,  日本動脈硬化学会 ,  日本心不全学会 ,  日本高血圧学会 ,  Japanese Society of Internal Medicine ,  American Heart Association ,  Japanese Circulation Society
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