Ito Masaaki

イトウマサアキ | Ito Masaaki

Affiliation and department：

Research field (2)： Hematology and oncology , Cardiology

Research keywords (7)：動脈硬化 , 高血圧学 , 心臓病態学 , 血管病態学 , Hypertension , Molecular Cardiology , Vascular Medicine

Research theme for competitive and other funds (7)：

虚血による血管新生・脈管形成のメカニズム
心血管リモデリングの分子機構
血管トーヌス制御の分子機構
Molecular Mechanisms of Vasculas Contraction and Relaxation
Mechanisms of Ischemia-induced Angiogenesis and Vasculogenesis

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MISC (98)：

K Yamawaki, M Ito, H Machida, N Moriki, R Okamoto, N Isaka, H Shimpo, A Kohda, K Okumura, DJ Hartshorne, et al. Identification of human CPI-17, an inhibitory phosphoprotein for myosin phosphatase. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001. 285. 4. 1040-1045
S Araki, M Ito, Y Kureishi, JH Feng, H Machida, N Isaka, M Amano, K Kaibuchi, DJ Hartshorne, T Nakano. Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2001. 441. 5. 596-603
Insulin utilizes nitric oxide/cGMP signaling pathway to inhibit Rho and its downstream targets in VSMC(共著). Journal of General Physiology. 2001. 91. 1475-1482
Inhibition by combined therapy with ticlopidine and aspirin of enhanced platelets aggregation during physical exercise in patients with coronary artery diseases(共著). Americal Heart Journal. 2001. 142. e1
Molecular cloning and analysis of 5'-flanking region of human MYPT1 gene(共著). Biochimica et Biophysica Acta. 2001. 1517. 424-429

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Patents (4)：

ミオシン軽鎖結合サブユニット類縁タンパク質およびその遺伝子(特開平10-234378)
ヒト由来のRho標的タンパク質Rhoキナーゼおよびその遺伝子(特開平10-201480)
Rho標的タンパク質Rhoキナーゼ(特開平10-113187)
ヒトミオシン軽鎖結合サブユニット、その遺伝子、および診断薬(特開平10-77299)

Books (8)：

Potential signal mediators for Ca<sup>2+</sup> sensitization of smooth muscle contraction : Rho-associated kinase,atypical protein kinase C,and arachidonic acid.(共著)
A functional view of smooth muscle JAI press Inc. 2000
Struchure and regulatory mechanisms of myosin phosphatase(共著)
Molecular mechanisms of smooth muscle contraction R.G.Landers 1999
Myosin light chain phosphatase
Academic Press 1996
Smooth muscle myosin phosphatase
Splinger-Verlag 1995
Phosphorylation of smooth muscle myosin Properties of myosin light Chain Kinase
Japan Sientific Societies Press/CRC Press 1992

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Works (5)：

Mechanisms of Ischemia-induced Angiogenesis In heart
2001 -
Rhoによるミオシンホスフマターゼ制御機構
1995 -
Regulation of Myosin Phosphatase by Small GTPase Rho
1995 -
血管トーヌス制御の分子機構
1990 -
Molecular Mechanisms of Vascular Contraction and Relaxation
1990 -

Professional career (1)：

Ph. D. (Mie University)

Committee career (5)：

2003 - 日本心不全学会評議員
2001 - 日本脈管学会評議員
2001 - 日本循環器学会評議員
1992 - 日本薬理学会学術評議員
日本心臓病学会特別正会員(FJCC) 2001-、評議員 2004-

Association Membership(s) (13)：

日本心不全学会 , 日本動脈硬化学会 , 日本高血圧学会 , 米国生化学分子生物学会 (American Society for Biochemistry and Molecular Biology) , 日本脈管学会 , 日本心臓病学会 , 国際心臓研究会(International Society for Heart Research) , 米国心臓病学会(American Heart Association) , 日本脈管作動物質学会 , 日本薬理学会 , 日本生化学会 , 日本循環器学会 , 日本内科学会

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