Rchr
J-GLOBAL ID:200901016575813757   Update date: Aug. 24, 2024

Dohgu Shinya

ドウグ シンヤ | Dohgu Shinya
Affiliation and department:
Research field  (2): Pharmacology ,  Clinical pharmacy
Research keywords  (3): Neurovascular Unit ,  Pericyte ,  Blood-Brain Barrier
Research theme for competitive and other funds  (15):
  • 2023 - 2026 Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes
  • 2021 - 2025 Prevention of impaired cognitive function by food factors
  • 2021 - 2024 病変型脳ペリサイトのαシヌクレイン処理能障害による頭部外傷後のパーキンソン病発症
  • 2019 - 2022 Involvement of activated brain pericytes induced by inflammatory bowel disease in the increased aggregation of alpha-synuclein in the brain.
  • 2016 - 2019 The brain pericytes-induced blood-brain barrier dysfunction and the central adverse effects in the chronic obstructive pulmonary disease
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Papers (73):
  • Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Yuki Goto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Yasufumi Kataoka, Shinya Dohgu. Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains. Biochemical and biophysical research communications. 2023. 645. 154-163
  • Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Yasufumi Kataoka, Shinya Dohgu. Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice. PloS one. 2023. 18. 2. e0281946
  • Koshun Inada, Mitsuhisa Koga, Ayano Yamada, Shinya Dohgu, Atsushi Yamauchi. Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice. Biochemical and biophysical research communications. 2022. 629. 1-5
  • Taira Matsuo, Rie Komori, Minami Nakatani, Shiori Ochi, Aya Yokota-Nakatsuma, Junichi Matsumoto, Fuyuko Takata, Shinya Dohgu, Yasuhiro Ishihara, Kouichi Itoh. Levetiracetam Suppresses the Infiltration of Neutrophils and Monocytes and Downregulates Many Inflammatory Cytokines during Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice. International journal of molecular sciences. 2022. 23. 14
  • Takata F, Nakagawa S, Matsumoto J, Dohgu S. Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction. Front Cell Neurosci. 2021. 15. 661838
more...
MISC (27):
Patents (3):
  • 血液脳関門透過性ペプチド
  • 血液脳関門障害症候群治療薬
  • 血液脳関門障害症候群治療薬
Books (1):
  • Birbrair A. (eds) Biology of Pericytes - Recent Advances. Stem Cell Biology and Regenerative Medicine, vol 68.
    Humana, Cham 2021
Education (1):
  • 2001 - 2004 Kyushu University Graduate School of Pharmaceutical Sciences Medico-Pharmaceutical Sciences
Professional career (2):
  • 博士(薬学) (九州大学)
  • Ph.D. (Kyushu University)
Work history (5):
  • 2020/10/01 - Fukuoka University Faculty of Pharmaceutical Sciences Professor
  • 2008/04/01 - 2020/09/30 Fukuoka University Faculty of Pharmaceutical Sciences Associate Professor
  • 2005/07/01 - 2008/03/31 Saint Louis University School of Medicine Postdoctoral Fellow
  • 2005/10/01 - 2006/03/31 Fukuoka University Advanced Materials Institutes 研究員
  • 2004/04/01 - 2005/09/30 Fukuoka University Advanced Materials Institutes Postdoctoral Fellow
Association Membership(s) (3):
日本薬理学会 ,  日本薬学会 ,  日本薬物動態学会
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