Nagatomo Toshihisa

• 致死性不整脈の発生に関与するイオンチャネルの機能解析
• Functional analysis of ion channel associated with lethal arrhythmia

• H. Takemasa, T. Nagatomo, H. Abe, K. Kawakami, T. Igarashi, T. Tsurugi, N. Kabashima, M. Tamura, M. Okazaki, B. P. Delisle, et al. Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome. BRITISH JOURNAL OF PHARMACOLOGY. 2008. 153. 3. 439-447
• K Kawakami, T Nagatomo, H Abe, K Kikuchi, H Takemasa, BD Anson, BP Delisle, CT January, Y Nakashima. Comparison of HERG channel blocking effects of various beta-blockers - implication for clinical strategy. BRITISH JOURNAL OF PHARMACOLOGY. 2006. 147. 6. 642-652
• K Kikuchi, T Nagatomo, H Abe, K Kawakami, HJ Duff, JC Makielski, CT January, Y Nakashima. Blockade of HERG cardiac K+ current by antifungal drug miconazole. BRITISH JOURNAL OF PHARMACOLOGY. 2005. 144. 6. 840-848
• Y Oginosawa, T Nagatomo, H Abe, N Makita, JC Makielski, Y Nakashima. Intrinsic mechanism of the enhanced rate-dependent QT shortening in the R1623Q mutant of the LQT3 syndrome. CARDIOVASCULAR RESEARCH. 2005. 65. 1. 138-147
• New onset of pacemaker dependency after permanent pacemaker implantation. PACE. 2004. 27:475-479

ｍore...

• - 1987 University of Occupational and Environmental Health, Japan School of Medicine
• - 1987 University of Occupational and Environmental Health, Japan Faculty of Medicine

• PhD (University of Occupational and Environmental Health, Japan)

• 1999 - 2001 University of Occupational and Environmental Health, Japan
• 1999 - 2001 University of Occupational and Environmental Health, Assistant Professor
• 2001 - - 産業医科大学 助教授
• 2001 - - University of Occupational and Environmental Health, Associate Professor
• 1996 - 1998 ウィスコンシン州立大学 研究員
1996 - 1998 University of Eosconsin, Research Associate
1992 - 1995 University of Occupational and Environmental Health, Japan
1992 - 1995 University of Occupational and Environmental Health, Instructor

日本生理学会 (国内) ,  日本心臓病学会 (国内) ,  日本心臓ペーシング電気生理学会(国内) ,  日本心電学会 ,  北米心臓ペーシング電気生理学会(NASPE) ,  米国循環器学会(AHA) ,  日本循環器学会 ,  日本内科学会 ,  Japan Society for Occupational Health ,  Japanese Society of Cardiac Pacing and Electrophysiology ,  NASPE-Heart Rhythm Society ,  American Heart Association ,  Japanese Circulation Society ,  Japanese Society of Internal Medicine