Nakajima Mitsunari

ナカジマミツナリ | Nakajima Mitsunari

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (14)：健康寿命延伸物質 , カロリー制限模放物 , 乳蛋白質 , 神経栄養因子 , APP , プレセニリン , 神経細胞死 , アルツハイマー病 , Milk protein , Neurotrophic factor , APP , Presenilin , Nerve cell death , Alzheimer disease

Research theme for competitive and other funds (13)：

2023 - 2026 ダブルコンジェニックSHRSP/Izmを用いた河内晩柑果皮の脳血管障害防御機構の解析
2022 - 2025 健康寿命延伸物質の探索 ~ドラッグリポジショニングの活用~
2020 - 2023 ダブルコンジェニックSHRSP/Izmを用いた柑橘成分の脳機能障害防御機構の解析
2019 - 2022 A proposed novel method for screening caloric restriction mimetics and its application
2016 - 2019 The effects of citrus-related compounds on global cerebral ischemic injury in SHRSP.

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Papers (66)：

Ayumi Kawamura, Akane Ito, Ayaka Takahashi, Atsushi Sawamoto, Satoshi Okuyama, Mitsunari Nakajima. Benproperine reduces IL-6 levels via Akt signaling in monocyte/macrophage-lineage cells and reduces the mortality of mouse sepsis model induced by lipopolysaccharide. Journal of pharmacological sciences. 2024. 156. 2. 125-133
Atsushi Sawamoto, Madoka Okada, Nanako Matsuoka, Satoshi Okuyama, Mitsunari Nakajima. Tipepidine activates AMPK and improves adipose tissue fibrosis and glucose intolerance in high-fat diet-induced obese mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024. 38. 5. e23542
Shiori Miyawaki, Atsushi Sawamoto, Satoshi Okuyama, Mitsunari Nakajima. Sulconazole induces pyroptosis promoted by interferon-γ in monocyte/macrophage lineage cells. Journal of pharmacological sciences. 2024. 154. 3. 166-174
Ayumi Kawamura, Atsushi Sawamoto, Satoshi Okuyama, Mitsunari Nakajima. Cloperastine Reduces IL-6 Expression via Akt/GSK3/Nrf2 Signaling in Monocytes/Macrophages and Ameliorates Symptoms in a Mouse Sepsis Model Induced by Lipopolysaccharide. Biological & pharmaceutical bulletin. 2024. 47. 10. 1699-1707
Toshiki Omasa, Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukawa. Effects of Citrus kawachiensis Peel in Frailty-like Model Mice Induced by Low Protein Nutrition Disorders. Antioxidants (Basel, Switzerland). 2023. 12. 3

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MISC (46)：

大政俊樹, 奥山聡, 武田大地, 天倉吉章, 菊地毅洋, 笹山新生, 澤本篤志, 内倉崇, 好村守生, 中島光業. Anti-inflammatory effect of ‘Ehime-kashi No. 48’. 日本農芸化学会大会講演要旨集(Web). 2023. 2023
澤本篤志, 土居紀子, 中西雅之, 天倉吉章, 奥山聡, 中島光業. N-Caffeoyltryptophanは脂肪細胞への糖取り込みを促進し耐糖能を改善する. 生体機能と創薬シンポジウム要旨集. 2023. 2023
中島光業, 門田尚子, 吉田明香里, 澤本篤志, 奥山聡. Ibudilast ameliorates inflammatory response in vivo and protects mice against death induced by LPS. 日本薬学会年会要旨集(Web). 2022. 142nd
奥山聡, 徳本睦樹, 大政俊樹, 澤本篤志, 中島光業. Effect of the components of citrus peel in the brain of senescence-accelerated mice. 日本薬学会年会要旨集(Web). 2022. 142nd
大政俊樹, 奥山聡, 澤本篤志, 中島光業. Neuroprotective effect of heptamethoxyflavone in brains of lipopolysaccharide-induced inflammatory model mice. 日本薬学会年会要旨集(Web). 2022. 142nd

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Education (2)：

Kanazawa University Faculty of Pharmaceutical Sciences
金沢大学大学院薬学研究科製薬化学専攻修士課程

Professional career (1)：

薬学博士 (金沢大学)

Work history (4)：

2017/04 - 現在 Matsuyama University Faculty of Pharmaceutical Sciences
2006/04 - 2017/03 Matsuyama University Faculty of Pharmaceutical Sciences
1998 - 東京都老人総合研究所研究員
1986 - 森永乳業株式会社入社

Association Membership(s) (2)：

THE JAPANESE PHARMACOLOGICAL SOCIETY , THE PHARMACEUTICAL SOCIETY OF JAPAN

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