Imai Hiroshi

イマイヒロシ | Imai Hiroshi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (2)： http://www.bio.sci.osaka-u.ac.jp/bio_web/lab_page/kon/ , http://www.bio.sci.osaka-u.ac.jp/bio_web/lab_page/kon/index-e.html

Research field (3)： Cell biology , Biophysics , Structural biochemistry

Research keywords (4)： cryo-EM , dynein , microtubule , Glutamate dehydrogenase

Research theme for competitive and other funds (7)：

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Papers (8)：

Osamu Kutomi, Ryosuke Yamamoto, Keiko Hirose, Katsutoshi Mizuno, Yuuhei Nakagiri, Hiroshi Imai, Akira Noga, Mohan Obbineni, Noemi Zimmermann, Masako Nakajima, et al. A dynein-associated photoreceptor protein prevents ciliary acclimation to blue light. Science Advances: Vol. 7, no. 9, eabf3621 DOI: 10.1126/sciadv.abf3621. 2021. 7. 9
Rie Ayukawa (*), Seigo Iwata (*), Hiroshi Imai (*), Shinji Kamimura, Masahito Hayashi, Kien Xuan Ngo, Itsushi Minoura, Seiichi Uchimura, Tsukasa Makino, Mikako Shirouzu, et al. GTP-dependent formation of straight oligomers leads to nucleation of microtubules. J Cell Biol 220 (4): e202007033. 2021. 220. 4
T. Sato, T. Shirane, Y. Wada, H. Imai, S. Kamimura. Development of phase contrast/dark-field microscopy with scanning laser illumination. J. Inst. Sci. Eng. Chuo Univ. 2019. 49
Hiroshi Imai, Tomohiro Shima, Kazuo Sutoh, Matthew L. Walker, Peter J. Knight, Takahide Kon, Stan A. Burgess. Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules. NATURE COMMUNICATIONS. 2015. 6. 8179
Hiroshi Imai, Akihiro Narita, Yuichiro Maeda, Trina A. Schroer. Dynactin 3D Structure: Implications for Assembly and Dynein Binding. JOURNAL OF MOLECULAR BIOLOGY. 2014. 426. 19. 3262-3271

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MISC (5)：

H. Imai, R. Kanazawa, R. Shimo-Kon, T. Kon. Two different linker conformations of the cytoplasmic dynein motor domain in the presence of ADP. Molecular Biology of the Cell. 2023. 35. Abstract #1094
H. Imai, M. Nishiyama, Y. Kaminoe, Y. Harada, T. Kon, S. Kamimura. Effects of high hydrostatic pressure to swimming sea urchin sperm flagella. Molecular Biology of the Cell. 2023. 35. Abstract #2608
Hiroshi IMAI, Etsuko MUTO. Dynamics of the Spontaneous Nucleation of Microtubules. Seibutsu Butsuri. 2023. 63. 6. 299-302
Etsuko Muto, Rie Ayukawa, Seigo Iwata, Hiroshi Imai, Shinji Kamimura, Ken Sekimoto, Gigant Benoit. GTP-Dependent Formation of Straight Oligomers Leads to Nucleation of Microtubules. BIOPHYSICAL JOURNAL. 2021. 120. 3. 12A-12A
今井洋, 昆隆英. 動物細胞に共通する細胞内の輸送システム. 生産と技術. 2018. 70. 4. 73-76

Books (1)：

Handbook of dynein (Second edition)
Jenny Stanford Publishing 2019 ISBN:9789814800013

Lectures and oral presentations (27)：

繊毛ダイニン・細胞質ダイニン・IFT ダイニンの構造的共通性と多様性
(生体運動研究合同班会議2024 2024)
繊毛微小管内部タンパク質 Rib43a は正常な繊毛運動と繊毛軸糸の物理的安定性に重要である
(生体運動研究合同班会議2024 2024)
Effects of high hydrostatic pressure to swimming sea urchin sperm flagella.
(2023 American Society for Cell Biology Annual Meeting 2023)
Two different linker conformations of the cytoplasmic dynein motor domain in the presence of ADP
(2023 American Society for Cell Biology Annual Meeting 2023)
14 to 16 protofilament GMPCPP-microtubules structures revealed by cryo-EM
(The 61st Annual Meeting of the Biophysical Society of Japan 2023)

ｍore...

Education (1)：

1997 - 2003 University of Tokyo Graduate School of Science Department of Biological Sciences

Professional career (1)：

Work history (5)：

2017/04 - 現在 Osaka University Graduate School of Science Department of Biological Sciences Assistant Professor
2015/04 - 2017/03 Chuo University Faculty of Science and Engineering Department of Biological Sciences Assistant Professor
2009/04 - 2015/03 University of Leeds, United Kingdom Astbury Centre for Structural Molecular Biology Research Fellow
2005/04 - 2009/03 Japan Science and Technology Agency Researcher
2003/04 - 2005/03 RIKEN Harima Institute Contract researcher

Awards (1)：

2016/03 - 15th Alpbach Motors Workshop, Myosin and Muscle, and other Motors. Alpbach Motor Meeting Award Direct observation of structures of dimeric dynein molecules stepping along microtubules

Association Membership(s) (3)：

American society for cell biology , Zoological Society of Japan , THE BIOPHYSICAL SOCIETY OF JAPAN

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