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J-GLOBAL ID：200901018013564820   Update date: Aug. 26, 2024

Tanabe Mitsuo

タナベ ミツオ | Tanabe Mitsuo
Affiliation and department：
Kitasato University

About Kitasato University


Job title： Associate Professor
Homepage URL  (1)： http://www.pharm.kitasato-u.ac.jp/pharmacology/
Research field  (1)： Pharmacology
Research keywords  (2)： 神経障害性疼痛 イオンチャンネル 電気生理 ,  Neuropathic pain Ion channels Electrophysiology
Research theme for competitive and other funds  (11)：
  • 2019 - 2022 Establishment of the drug discovery research for pruritus treatments targeting neurotransmitter pathways
  • 2015 - 2018 Synaptic mechanisms of pain relief by increasing inhibitory transmission in the spinal dorsal horn
  • 2011 - 2013 Pathophysiological and pharmacological assessment of synaptic transmission in chronic pain states
  • 2008 - 2010 Basic research for the establishment of the pharmacological assessment for drug development based on the study on synaptic transmission in chronic pain states
  • 2008 - 2010 Spinal Cord Injury : Establishment of Measurement for Electrophysiological Function and Pharmacological Evaluation of Drugs
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Papers (68)：
  • Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Selective inhibition of A-fiber-mediated excitatory transmission underlies the analgesic effects of KCNQ channel opening in the spinal dorsal horn. Neuropharmacology. 2024. 254. 109994-109994
  • Ryosuke Nakamura, Takashi Iwai, Yasukazu Takanezawa, Tatsuya Shirahata, Naruki Konishi, Yuka Ohshiro, Shimpei Uraguchi, Mitsuo Tanabe, Yoshinori Kobayashi, Kenji Sakamoto, et al. Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice. Toxicology. 2024. 506. 153867-153867
  • Takashi Iwai, Rei Mishima, Shigeto Hirayama, Honoka Nakajima, Misa Oyama, Shun Watanabe, Hideaki Fujii, Mitsuo Tanabe. SYK-623, a δ Opioid Receptor Inverse Agonist, Mitigates Chronic Stress-Induced Behavioral Abnormalities and Disrupted Neurogenesis. Journal of Clinical Medicine. 2024. 13. 2. 608-608
  • Motoki Morita, Shun Watanabe, Natsumi Nomura, Kanako Takano-Matsuzaki, Misa Oyama, Takashi Iwai, Mitsuo Tanabe. Sulfatide-selectin signaling in the spinal cord induces mechanical allodynia. Journal of neurochemistry. 2023. 164. 5. 658-670
  • Misa Oyama, Shun Watanabe, Takashi Iwai, Mitsuo Tanabe. Distinct synaptic mechanisms underlying the analgesic effects of γ-aminobutyric acid transporter subtypes 1 and 3 inhibitors in the spinal dorsal horn. Pain. 2022. 163. 2. 334-349
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MISC (132)：
  • 宮田 直樹, 田辺 光男, 内田 恵理子, 川崎 ナナ. 薬の名前 ステムを知れば薬がわかる(追補-11) 神経系作用薬を定義する新しいステム「-fenacin」、「-fensine」、「-isant」、「-laner」. PHARM TECH JAPAN. 2022. 38. 8. 1311-1316
  • 宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs New stems defining specific enzyme inhibitors-2: -parstat, -polstat, -telstat, -tristat, -xestat, etc. Pharm Tech Japan. 2021. 37. 1
  • 宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. A common stem defining enzyme inhibitors: -stat(-). Pharm Tech Japan. 2021. 37. 5
  • 宮田直樹, 頭金正博, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs Special edition: Therapeutic agents for COVID-19. Pharm Tech Japan. 2021. 37. 8
  • 宮田直樹, 田辺光男, 内田恵理子, 川崎ナナ. Stems used in drug names: For the better understanding of pharmacological actions of drugs Special edition: Therapeutic agents for COVID-19, Part 2. Pharm Tech Japan. 2021. 37. 9
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Books (2)：
  • パートナー薬理学
    南江堂 2024 ISBN:9784524404285
  • パートナー薬理学
    南江堂 2019 ISBN:9784524403523
Lectures and oral presentations  (40)：
  • スフィンゴ糖脂質による痛みの調節メカニズムの解析
    (痛み研究会2023:痛みの統合的理解とその制御に向けて 2024)
  • Sialic acid degradation in the inflamed skin attenuates the number of the epidermal nerve fibers and inflammatory pain via calcitonin gene related peptide receptors
    (2023)
  • 海馬-側坐核系の保護によるδオピオイド受容体逆作動薬SYK-623の抗うつ作用
    (第53回日本神経精神薬理学会年会 2023)
  • δオピオイド受容体作動薬KNT-127の睡眠に対する作用
    (第42回鎮痛薬・オピオイドペプチドシンポジウム 2023)
  • P2X7受容体作動薬BzATPの不安惹起作用
    (第42回鎮痛薬・オピオイドペプチドシンポジウム 2023)
ｍore...
Education (4)：
  • - 1987 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • - 1987 The University of Tokyo Faculty of Pharmaceutical Sciences, The University of Tokyo
  • - 1985 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
  • - 1985 The University of Tokyo Graduate School of Pharmaceutical Sciences
Professional career (1)：
  • 博士(薬学) (東京大学)
Work history (5)：
  • 2010/04 - 現在 Kitasato University School of Pharmaceutical Sciences
  • 2002/09 - 2010/03 - 名古屋市立大学大学院薬学研究科 助教授・准教授
  • 1987/04 - 2002/08 三共株式会社
  • 1987 - 2002 Sankyo, Co., Ltd.
  • 2002 - - Nagoya City University
Committee career (1)：
  • 2001 - 日本薬理学会 評議員
Association Membership(s) (6)：
北米神経科学会 ,  日本神経科学学会 ,  日本薬理学会 ,  Society for Neuroscience ,  Japan Neuroscience Society ,  The Japanese Pharmacological Society
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