Research field (3):
Cell biology
, Molecular biology
, Genomics
Research keywords (3):
Cell systems
, Genome
, Retrotransposon
Research theme for competitive and other funds (4):
2016 - 2018 Screening for functional protein-encoding ORFs located outside coding regions in the human genome
2012 - 2014 ドメイン構造をもたない天然変性タンパク質群に対する構造機能相関解析
2010 - 2011 ドメイン構造をもたない天然変性タンパク質群における構造機能相関解析
2006 - 2007 ヒトレトロポゾンL1タンバク質と宿主細胞機能とのクロストーク
Papers (22):
Tomoyuki Ohno, Taichi Akase, Shunya Kono, Hikaru Kurasawa, Takuto Takashima, Shinya Kaneko, Yasunori Aizawa. Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells. Nature communications. 2022. 13. 1. 4219-4219
Hikaru Kurasawa, Tomoyuki Ohno, Ryusei Arai, Yasunori Aizawa. A guideline and challenges toward the minimization of bacterial and eukaryotic genomes. CURRENT OPINION IN SYSTEMS BIOLOGY. 2020. 24. 127-134
Shinya Kaneko, Hiromi Fukushima, Misako Nakahama, Satomi Asano, Yasumasa Miyazaki, Yasunori Aizawa, Mitsuhiro Itaya. DNA synthesis by fragment assembly using extra-cellular DNA delivered by artificial controlled horizontal transfer. Journal of biochemistry. 2018. 163. 4. 305-312
Shohei Kitano, Hikaru Kurasawa, Yasunori Aizawa. Transposable elements shape the human proteome landscape via formation of cis-acting upstream open reading frames. Genes to cells : devoted to molecular & cellular mechanisms. 2018. 23. 4. 274-284