Rchr
J-GLOBAL ID：200901018274751953   Update date: Apr. 10, 2024

Okamoto Takayuki

オカモト タカユキ | Okamoto Takayuki
Affiliation and department：
Shimane University Faculty of Medicine, School of Medicine

About Shimane University Faculty of Medicine, School of Medicine


Homepage URL  (1)： http://www.med.shimane-u.ac.jp/pharmacology/index.html
Research field  (3)： Medical biochemistry ,  Pharmacology ,  Pathobiochemistry
Research keywords  (5)： 炎症 ,  メカノバイオロジー ,  血管内皮 ,  血栓止血 ,  Drug Delivery System
Research theme for competitive and other funds  (26)：
  • 2020 - 2023 YAP阻害による敗血症性臓器障害の制御
  • 2020 - 2023 非アルコール性脂肪性肝疾患において発現が増加するmiRNAの機能解析
  • 2019 - 2022 Molecular mechanism of cooperation between endothelial cell stiffness and functions.
  • 2019 - 2022 Development of a prediction system of systemic disease using AI technology based on oral flora.
  • 2018 - 2021 Establishment of evaluation method for arteriosclerotic lesions by measuring the "hardness" of blood vessels using an atomic force microscope
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Papers (101)：
  • Kouji Kita, Kunihiro Asanuma, Takayuki Okamoto, Eiji Kawamoto, Koichi Nakamura, Tomohito Hagi, Tomoki Nakamura, Motomu Shimaoka, Akihiro Sudo. A Novel Approach to Reducing Lung Metastasis in Osteosarcoma: Increasing Cell Stiffness with Carbenoxolone. Current issues in molecular biology. 2023. 45. 5. 4375-4388
  • Usuda Haruki, Niibayashi Tomomi, Morita Yusuke, Endo Akihiro, Okamoto Takayuki, Tanabe Kazuaki, Wada Koichiro. Patients with cardiovascular diseases exhibit distinct characteristics in their oral microbiome and are more susceptible to infections by pathogenic bacteria. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 3-B-P-046
  • Okamoto Takayuki, Katsube Yukiko, Hattori Mai, Usuda Haruki, Ota Junichi, Nikai Tetsuro, Wada Koichiro. Hornerin expressed in endothelial cells implicates in angiogenesis. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 3-B-O19-2
  • 和田 孝一郎, 臼田 春樹, 岡本 貴行, 新林 友美. オンライン薬理学実習 シミュレーターを活用した薬理学実習・動物実習の有用性?. 日本臨床薬理学会学術総会抄録集. 2022. 43回. 2-3
  • Kunihiro Asanuma, Tomoki Nakamura, Koichi Nakamura, Tomohito Hagi, Takayuki Okamoto, Kouji Kita, Yumi Matsuyama, Keisuke Yoshida, Yumiko Asanuma, Akihiro Sudo. Compound Library Screening for Synergistic Drug Combinations: mTOR Inhibitor and Proteasome Inhibitor Effective Against Osteosarcoma Cells. Anticancer research. 2022. 42. 9. 4319-4328
ｍore...
MISC (52)：
  • 岡本貴行, 臼田春樹, 和田孝一郎. 血管内皮細胞の硬さとギャップ結合におけるYAPの役割. 日本薬理学雑誌. 2023. 158. Supplement
  • 臼田春樹, 新林友美, 岡本貴行, 和田孝一郎. 好酸球性食道炎患者における高病原性口腔内細菌の保菌および口腔内細菌叢についての基礎的検討. 日本薬理学雑誌. 2022. 157. Supplement
  • JAHAN Israt, OKAMOTO Takayuki, USUDA Haruki, TANAKA Tetsuya, NIIBAYASHI Tomomi, NAKAJIMA Atsushi, WADA Koichiro. MiR-126-3p and MiR-199a-3p Promote Lipid Accumulation in 3T3-L1 Adipocytes via Regulating HIF-1α and C/EBPα Expression. Shimane Journal of Medical Science (Web). 2022. 39. 4
  • USUDA Haruki, KANDA Syoma, OKAMOTO Takayuki, WADA Koichiro. Lacking dietary fiber enhances sensitivity to inflammatory stimuli, that results in intestinal hyper-permeability. 日本薬理学会年会(Web). 2021. 94th
  • Takayuki Okamoto, Eiji Kawamoto, Haruki Usuda, Tetsuya Tanaka, Tetsuro Nikai, Kunihiro Asanuma, Koji Suzuki, Motomu Shimaoka, Koichiro Wada. RECOMBINANT HUMAN SOLUBLE THROMBOMODULIN REDUCES LIPOPOLYSACCHARIDE-INDUCED ENDOTHELIAL CELL STIFFENING AND MONOCYTE. SHOCK. 2020. 53. 18-19
ｍore...
Professional career (1)：
  • master (Osaka University)
Work history (1)：
  • 2004/08 - ~三重大学大学院医学系研究科 助教2013年12月~三重大学大学院医学系研究科 研究科内講師
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