Fujita Tomoe

フジタトモエ | Fujita Tomoe

Affiliation and department：
Job title： Professor

Research field (2)： Pharmaceuticals - chemistry and drug development , Pharmacology

Research keywords (16)：尿細管分泌 , 有機アニオントランスポータ , チトクロームP450 , 薬物トランスポータ , ダイセクション , 接合尿細管 , カルシウム動態 , カリクレイン分泌 , renal tubular secretion , organic anion transporter , cytvhrome P450 , drug transporter , dissection , connecting tubule , calcium imaging , kallikrein secretion

Research theme for competitive and other funds (18)：

2021 - 2024 間質性膀胱炎の肥満細胞関連因子は、膀胱知覚亢進に寄与するか
2019 - 2023 Potential of amino acid transporter as a marker for inflammation of intestinal mucosa
2014 - 2018 Roles of bioactive lipids in regulation of lymphatic plasticity
2011 - 2015 Roles of prostanoids in facilitation of lymphangiogenesis and lymph node metastasis
2011 - 2013 Examination for genomic biomarkers of intestinal and renal drug transporters aiming for the personalized medicine

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Papers (59)：

Keitaro Hayashi, Yoshimasa Nakazato, Motoshi Ouchi, Tomoe Fujita, Hitoshi Endou, Masayuki Chida. Antitumor effect of dimethyl itaconate on thymic carcinoma by targeting LDHA-mTOR axis. Life sciences. 2021. 282. 119847-119847
ASUKA MORITA, MOTOSHI OUCHI, KEITARO SATOH, SHUNSUKE KOBAYASHI, MISAO TERADA, HIDEFUMI WAKASHIN, HIROE KON, KEITARO HAYASHI, NAOHIKO ANZAI, AKIRA SHIMIZU, et al. The Effects of Trypsin Inhibitor on Insulin Secretion Using Rat Pancreas in an Organ Bath. In Vivo. 2021. 35. 5. 2551-2558
Yuji Kumagai, Tomoe Fujita, Mika Maeda, Yoshinobu Sasaki, Makoto Nagaoka, Jinhong Huang, Toru Takenaka, Masaki Kawai. A Drug-Drug Interaction Study to Evaluate the Effect of TAS-303 on CYP3A Activity in the Small Intestine and Liver. Journal of clinical pharmacology. 2020. 60. 6. 702-710
Takuya Yumizaki, Mika Maeda, Tomoe Fujita, Hiroyoshi Kakuyama, Yuji Kumagai. A 3-Part Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DSP-6952 in Healthy Japanese Subjects and Those With ≤3 Spontaneous Bowel Movements per Week. Clinical pharmacology in drug development. 2020. 9. 3. 353-365
Naoyuki Otani, Shigeru Toyoda, Masashi Sakuma, Keitaro Hayashi, Motoshi Ouchi, Tomoe Fujita, Naohiko Anzai, Atsushi Tanaka, Koichi Node, Naoto Uemura, et al. Effects of uric acid on vascular endothelial function from bedside to bench. Hypertension research : official journal of the Japanese Society of Hypertension. 2018. 41. 11. 923-931

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MISC (85)：

Motoshi Ouchi, Kenzo Oba, Hideki Suganami, Akihiro Yoshida, Tomoe Fujita, Tatsuya Suzuki, Masahiro Yasutake, Kohei Kaku. This is in reply to the Letter by Kahathuduwa et al. titled “Unaccounted for regression to the mean renders conclusion of article titled ‘Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor Tofogliflozin’ unsubstantiated”. Diabetes, Obesity and Metabolism. 2018. 20. 8. 2041-2042
Mika Maeda, Mika Maeda, Mika Maeda, Tomoe Fujita, Hideki Amano, Harue Kohara, Akira Yamazaki, Akira Yamazaki, Takeshi Hirayama, Masakazu Kuroyama, et al. Pharmacokinetics and pharmacodynamics of a single dose of scopolamine ointment applied to the postauricular area in healthy subjects. Japanese Journal of Clinical Pharmacology and Therapeutics. 2018. 49. 53-58
大谷直由, 池田信人, 李佩俐, 大内基司, 藤田朋恵, 安西尚彦, 久留一郎. プロテアソーム阻害薬がモノカルボン酸トランスポーター9蛋白安定性に及ぼす効果. 痛風と核酸代謝. 2017. 41. 1. 141-141
中村裕二, 杉山篤, 橋本大哉, 藤田朋恵, 熊谷雄治. 新規キサンチンオキシダーゼ阻害剤トピロキソスタットの日本人健康成人におけるQT/QTc評価試験. 臨床薬理. 2013. 44. Supplement. S231-S231
Hideki Amano, Yoshio Mastui, Yoshiya Ito, Fumihiro Ogawa, Tomoe Fujita, Masafumi Shibuya, Yuji Kumagai, Masataka Majima. ROLES OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 SIGNALING IN COMPENSATORY CONTRALATERAL LUNG GROWTH AFTER UNILATERAL PNEUMONECTOMY. RESPIROLOGY. 2013. 18. 38-38

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Books (2)：

健康管理と臨床検査-早期診断を目指して-
宇宙堂八木書店 2005
H.pylori時代の消化性潰瘍の治療
日本メディカルセンター 2000

Professional career (1)：

医学博士

Association Membership(s) (6)：

日本薬学会 , American Society for Clinical Pharmacology and Therapeutics (ASCPT) , 日本臨床薬理学会 , 日本薬理学会 , 日本内科学会 , American Society for Clinical Pharmacology and Therapeutics (ASCPT)

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