Kaneyama Shuri

カネヤマシュリ | Kaneyama Shuri

Homepage URL (1)： https://sites.google.com/view/shurikanayama/project

Research field (3)： Tumor biology , Cell biology , Medical biochemistry

Research theme for competitive and other funds (19)：

2024 - 2028 老化関連遺伝子を標的としたアンチセンス核酸によるMASH病態改善機構の解明
2024 - 2027 肝線維症治療用アンチセンス核酸による肝機能改善メカニズムの解明と治療薬の性能向上に向けた新技術開発
2021 - 2024 Development of the antisense nucleic acid aiming to treat liver fibrosis via extracellular matrix remodeling
2020 - 2023 TGF-β 誘導性分子を標的とした新規肺線維症治療戦略の構築
2019 - 2022 Investigation of the role of carcinoma-associated fibroblasts in colorectal cancer

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Papers (45)：

Phuong Tran Pham, Oyunbileg Bavuu, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Takayuki Yamamoto, Kenichiro Otsuka, Kumiko Suto, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, et al. Innate Immune System Regulated by Stimulator of Interferon Genes, a Cytosolic DNA Sensor, Regulates Endothelial Function. Journal of the American Heart Association. 2023. 12. 22. e030084
Aya Miyauchi, Masahito Noguchi, Xiao-Feng Lei, Masashi Sakaki, Momoko Kobayashi-Tanabe, Shogo Haraguchi, Akira Miyazaki, Joo-Ri Kim-Kaneyama. Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13. Scientific reports. 2023. 13. 1. 7446-7446
Phuong Tran Pham, Oyunbileg Bavuu, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Takayuki Yamamoto, Kenichiro Otsuka, Kumiko Suto, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, et al. Innate Immune System Regulated by STING, a Cytosolic DNA Sensor, Regulates Endothelial function. J Am Heart Assoc. in press. 2023
Takuro Miyazaki, Yoshitaka Taketomi, Takayoshi Higashi, Hirokazu Ohtaki, Takashi Takaki, Koji Ohnishi, Masahiro Hosonuma, Nozomu Kono, Risako Akasu, Shogo Haraguchi, et al. Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking. Arteriosclerosis, Thrombosis, and Vascular Biology. 2022
Phuong Tran Pham, Daiju Fukuda, Sachiko Nishimoto, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Yutaka Takahashi, Tomohito Sato, Kimie Tanaka, Kumiko Suto, Yutaka Kawabata, et al. STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases. European heart journal. 2021. 42. 42. 4336-4348

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MISC (12)：

坂木理, 金山朱里, 野口雅仁, 冨士貴弘, 音山裕美, 中島陽子, 杉浦育也, 荒井潤, 梶原敦, 市川雪, et al. 中鎖脂肪酸が及ぼす代謝性肝疾患への影響の検討. 肝臓. 2023. 64. Suppl.1. A411-A411
野口雅仁, 坂木理, 金山朱里. NASH/ASHの病態解明とTransrational Research 非アルコール性脂肪肝炎(NASH)におけるHic-5の病態への関与と治療標的としての可能性の検討. 肝臓. 2023. 64. Suppl.1. A207-A207
宮崎拓郎, 原口省吾, 金山朱里, 宮崎章. 脂質異常症に起因するリンパ管内皮細胞のタンパク質恒常性低下は動脈硬化症を増悪化する. 脂質生化学研究. 2019. 61. 173-174-174
宮崎拓郎, 原口省吾, 森戸大介, 金山朱里, 宮崎章. リンパ管内皮細胞を起点とした動脈硬化症の発症機構. 日本動脈硬化学会総会・学術集会プログラム・抄録集(Web). 2019. 51st. 252 (WEB ONLY)
M. Shimabukuro, C. Okawa, X. F. Lei, J. R. Kim-Kaneyama, H. Yamada, H. Kurobe, D. Fukuda, M. Sato, T. Kitagawa, M. Sata. EFFECTS OF EZETIMIBE ON OXIDIZED CHOLESTEROL COMPONENTS IN EPICARDIAL FAT AND MYOCARDIUM: A GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS. ATHEROSCLEROSIS. 2014. 235. 2. E113-E113

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Patents (2)：

Hic-5インヒビターの新規用途
Novel use of Hic-5 inhibitor

Books (1)：

血管生物医学事典
2011

Professional career (1)：

(BLANK) (Showa University)

Work history (4)：

2015/11 - 現在 Showa University School of Medicine, Biochemistry
2009/01 - 2015/10 Showa University School of Medicine, Biochemistry
2007/04 - 2008/12 Showa University School of Pharmacy
2001/04 - 2007/03 Showa University School of Pharmacy

Committee career (2)：

2013 - 現在日本血管生物医学会評議員
2013 - 現在日本動脈硬化学会評議員

Awards (9)：

2017/03 - 公益財団法人日中医学協会調査共同研究等助成金
2014/01 - 公益財団法人昭和大学医学・医療振興財団医学研究助成
2013/05 - 富山県ひとづくり財団第30回とやま賞
2013 - 日本心臓財団入澤宏・彩記念研究奨励
2013 - 武田科学振興財団医学系研究奨励

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