Rchr
J-GLOBAL ID：200901019240740452
Update date: Nov. 05, 2024
Sohtome Yoshihiro
ソウトメ ヨシヒロ | Sohtome Yoshihiro
Affiliation and department：
Job title：
Professor
Homepage URL (2)：
https://sohtome-lab.sk.ritsumei.ac.jp
,
https://sohtome-lab.sk.ritsumei.ac.jp/en
Research field (3)：
Synthetic organic chemistry
, Chemical biology
, Biochemistry
Research keywords (7)：
有機合成化学
, 不斉触媒
, 化学生物学
, Computational chemistry
, Chemical Biology
, Asymmetric Catalysis
, Organic Chemistry
Research theme for competitive and other funds (15)：
- 2022 - 2026 Dynamic chemical control of protein methylation
- 2022 - 2025 Synergistic effects induced by neo-PTMs
- 2022 - 2025 In-cell chemical network driven by neo-PTMs
- 2018 - 2022 Seed compounds exploratory empowered by catalysis
- 2017 - 2022 Synthetic strategy for chemical methylome analyses
- 2018 - 2021 触媒反応を駆使した生物活性シード創出への挑戦
- 2018 - 2020 Centrochiral transition metal complexes for catalytic asymmetric reactions
- 2015 - 2018 Development of the chemical detectors and inhibitors for protein methylation toward chemical epigenomics
- 2011 - 2016 Development of tandem-type efficient organocatalysis based on the flexible catalyst structures: Application to the synthesis of natural products and drugs.
- 2012 - 2015 Development of the oxidative asymmetric catalysis by using transition metal complexes
- 2010 - 2011 Development of Dynamic Asymmetric Organocatalysis and Their Mechanistic Studies
- 2007 - 2008 多点認識触媒を用いる不斉炭素骨格構築法の確立と量産型医薬合成プロセスへの展開
- 2006 - 2007 希土類金属触媒を用いるニトロアルドール反応での不斉四置換炭素構築反応の開発
- 2003 - 2007 Innovational Asymmetric Catalysis縲廾ptimization and New Development
- 2005 - 2006 新規有機分子触媒の開発と環境調和型不斉炭素-炭素結合反応への展開
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Papers (57)：
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Minoru Ueda, Satoshi Takahashi, Junko Ishida, Ayumi Yamagami, Takeshi Nakano, Florian Pünner, Mai Akakabe, Yoshihiro Sohtome, Atsushi J. Nagano, Mikiko Sodeoka, et al. A Pyrazole Partially Induces Brassinosteroid-Related Gene Expression, Leading to Salt Stress Sensitivity. Journal of Plant Growth Regulation. 2024
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Florian Pünner, Yoshihiro Sohtome, Yanzong Lyu, Daisuke Hashizume, Mai Akakabe, Mami Yoshimura, Yoko Yashiroda, Minoru Yoshida, Mikiko Sodeoka. Catalytic Aerobic Carbooxygenation for the Construction of Vicinal Tetrasubstituted Centers: Application to the Synthesis of Hexasubstituted γ-Lactones. Angewandte Chemie International Edition. 2024
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Yoshihiro Sohtome, Mikiko Sodeoka. Catalytic oxidative carbon-carbon bond-formations of benzene-1,2-diols. Pure and Applied Chemistry. 2023. 96. 1. 5-21
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Tadahiro Shimazu, Rei Yoshimoto, Kaoru Kotoshiba, Takehiro Suzuki, Shogo Matoba, Michiko Hirose, Mai Akakabe, Yoshihiro Sohtome, Mikiko Sodeoka, Atsuo Ogura, et al. Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism. Genes & Development. 2023. 37. 724-742
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Yoshihiro Sohtome, Shinsuke Komagawa, Ayako Nakamura, Daisuke Hashizume, Sylvain Lectard, Mai Akakabe, Yoshitaka Hamashima, Masanobu Uchiyama, Mikiko Sodeoka. Experimental and Computational Investigation of Facial Selectivity Switching in Nickel-Diamine-Acetate-Catalyzed Michael Reactions. The Journal of Organic Chemistry. 2023. 88. 7764-7773
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MISC (34)：
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五月女宜裕, 菅原真純, 大西理華子, 澤村美紀, 赤壁麻依, 袖岡幹子. 持続性ラジカルとカテコールとの酸化的クロスカップリングに関する機構解析. 有機合成化学協会関東支部シンポジウム: 第84回東京農工大シンポジウム講演要旨集. 2023
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五月女 宜裕. メチル化基質探索のための人工的化学修飾の導入. 日本薬学会第143回要旨集. 2023
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Yoshihiro Sohtome, Masumi Sugawara, Miki Sawamura, Mai Akakabe, Boobalan Ramadoss, Mikiko Sodeoka. Aerobic Cross-Dehydrogenative Coupling of Catechols with Persistent Radicals. 2023
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Yoshihiro Sohtome, Tetsuya Ezawa, Daisuke Hashizume, Masaya Adachi, Mai Akakabe, Hiroyuki Koshino, Mikiko Sodeoka. Dynamic catalytic diastereoconvergent (3+2) cycloaddition with alpha-keto ester enolates. 2022
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Yoshihiro SOHTOME. Dynamic Diastereoconvergent Catalysis. 2021. 74. 860-860
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Books (6)：
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Designed Molecular Space in Material Science and Catalysis
Springer 2018
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実験医学別冊 エピジェネティクス実験スタンダード: もう悩まない!ゲノム機能制御の読み解き方
羊土社 2017
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化学の要点シリーズ18 基礎から学ぶケミカルバイオロジー
共立出版 2016
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Science of Synthesis Reference Library, Asymmetric Organocatalysis 2; Brønsted Base and Acid Catalysts, and additional Topics
2012
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Comprehensive Chirality
Elsevier 2012
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Lectures and oral presentations (48)：
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動的反応化学の新展開
(第44回有機合成若手セミナー: 明日の有機合成を担う人のために 2024)
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遷移金属錯体触媒を用いる動的不斉反応
(日本化学会第104春季年会 (2024) 特別企画 2024)
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境界領域への挑戦から探る動的反応化学
(立命館大学生命科学部: 超分子創製化学セミナー (第92回) 2024)
-
メチル化基質探索のためのneo-PTMsプローブ
(第96回日本生化学会大会 2023)
-
SOMO-HOMO level inversion
(2023)
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Education (3)：
- 2003 - 2006 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
- 2001 - 2003 The University of Tokyo Graduate School of Agricultural and Life Sciences
- 1997 - 2001 Keio University Faculty of Science and Technology Department of Chemistry
Professional career (1)：
Work history (14)：
- 2024/04 - 現在 Ritsumeikan University College of Llife Science Professor
- 2018/04 - 2024/03 国立研究開発法人理化学研究所 袖岡有機合成化学研究室 専任研究員
- 2023/04 - 2023/09 Saitama University Graduate School of Science and Engineering
- 2021/04 - 2021/09 Saitama University
- 2020/04 - 2021/03 Kyoto University Institute for Chemical Research
- 2019/04 - 2019/09 Saitama University
- 2018/09 - 2018/09 Rikkyo University
- 2011/04 - 2018/03 理化学研究所 袖岡有機合成化学研究室 研究員
- 2017/04 - 2017/09 Saitama University
- 2013/09 - 2014/03 埼玉大学 非常勤講師
- 2009/04 - 2011/03 東京農工大学工学府 生命有機化学講座 (長澤和夫 教授) 特任助教
- 2008/04 - 2009/03 Yale大学 化学科、Andrew D. Hamilton研究室 日本学術振興会海外特別研究員
- 2007/04 - 2008/03 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2006/04 - 2007/03 東京大学大学院薬学系研究科 有機合成化学研究室 (柴崎正勝教授) 流動助手
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Committee career (8)：
Awards (11)：
- 2023/12 - ICCEOCA-16: The 16th International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award from Taiwan Ni(II)-catalyzed Diastereoconvergent (3 + 2) Cycloaddition of alpha-Ketoester Enolates
- 2022/03 - RIKEN RIKEN BAIHO Award Development of Dynamic Catalytic Asymmetric Diastereoconvergent Reactions
- 2018/06 - JSPS program, “Precisely Designed Catalysts with Customized Scaffolding” Lectureship Award 2018 "Controlling Chiral Environments Constructed by Molecular Catalysis and Enzymes"
- 2016/01 - Georg Thieme Verlag Stuttgart Thieme Chemistry Journals Award
- 2015/10 - MSD Life Science Foundation, Banyu Chemist Award "Dynamically Tunable Asymmetric Organocatalysis Controlled by Conformationally Flexible Organocatalysts"
- 2014/02 - The Society of Synthetic Organic Chemistry Incentive Award in Synthetic Organic Chemistry, Japan
- 2013/10 - Eisai Award for Synthetic Organic Chemistry Japan (2013)
- 2011 - Chemical Society Japan, CSJ Award for Young Scholar Lecture Series
- 2007 - Elsevier, Tetrahedron Letters Most Cited Paper 2004-2007 Award "Development of Bis-thiourea-type Organocatalyst for Asymmetric Baylis-Hillman Reaction"
- 2006/03 - The Chemical Society of Japan, CSJ Student Presentation Award (2006)
- 2006 - Elsevier, Tetrahedron Letters Most Cited Paper 2003-2006 Award "Development of Bis-thiourea-type Organocatalyst for Asymmetric Baylis-Hillman Reaction"
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Association Membership(s) (7)：
日本エピジェネティクス研究会
, JAPANESE SOCIETY FOR CHEMICAL BIOLOGY
, KINKI CHEMICAL SOCIETY, JAPAN
, アメリカ化学会
, 有機合成化学協会
, 日本薬学会
, 日本化学会
