Rchr
J-GLOBAL ID:200901019716760465
Update date: Jun. 19, 2024
SHIRAKAWA HIDEKI
シラカワ ヒデキ | SHIRAKAWA HIDEKI
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://rainbow.pc.uec.ac.jp/
Research field (4):
Clinical pharmacy
, Physiology
, Cell biology
, Biophysics
Research keywords (4):
Bioimaging
, Cell Biology
, バイオイメージング
, 細胞生理学
Research theme for competitive and other funds (12):
- 2022 - 2025 生細胞で二次メッセンジャー濃度を自由自在に制御する手法の開発と応用
- 2015 - 2017 Development of IP3 clamp method
- 2009 - 2011 Functional coupling between Ca^<2+> influx anf Ca^<2+> release during Ca^<2+> oscillatons in fertilized mammalian eggs
- 2007 - 2009 Advanced Imaging Method of Light Source Distributions in Biological Tissues
- 2006 - 2006 生細胞分光イメージングと多変量解析法による多重蛍光の定量的分離解析システムの開発
- 2004 - 2006 Characterization and functional analysis of phospholipase C-zeta, a candidate of mammalian egg-activating sperm factor
- 2000 - 2001 カルシウム遊離に伴うin situ小胞体の電気的挙動に関する光学的手法による解析
- 1997 - 1998 哺乳類精子活性化過程で機能する二次メッセンジャーとイオンチャネルの同定
- 1997 - 1998 精子活性化の細胞内メカニズムの解明への直接的なアプローチ
- 1996 - 1997 Identification of sperm-derived egg-activating factor and analysis of molecular mechanisms of intracellular Ca^<2+> increase at fertilization of mammalian eggs
- 1993 - 1994 Physiological Study of the Mechanism Involved in Ca^<2+> Waves and Ca^<2+> Oscillations in Fertilized Mammalian Eggs
- 1991 - 1991 哺乳動物卵に於ける細胞内Caイオン遊離機構の生理学的解析
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Papers (71):
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Ryotaro Kano, Ayaka Tabuchi, Yoshinori Tanaka, Hideki Shirakawa, Daisuke Hoshino, David C Poole, Yutaka Kano. In vivo cytosolic H2O2 changes and Ca2+ homeostasis in mouse skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology. 2023
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Tabuchi, A, Tanaka, Y, Takagi, R, Shirakawa, H, Shibaguchi, T, Sugiura, T, Poole, D.C, Kano, T. Ryanodine receptors mediate high intracellular Ca2+ and some myocyte damage following eccentric contractions in rat fast twitch skeletal muscle. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2022. 322. 1. R14-R27
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Matsu-ura, T, Shirakawa, H, Suzuki, K.G.N, Miyamoto, A, Sugiura, K, Michikawa, T, Kusumi, A, Mikoshiba, K. Dual-FRET imaging of IP3 and Ca2+ revealed Ca2+-induced IP3 production maintains long lasting Ca2+ oscillations in fertilized mouse eggs. Scientific Reports. 2019. 9. 1. 4829
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Wakizaka, M, Eshima, H, Tanaka, T, Shirakawa, H, Poole, D.C, Kano, Y. In vitro Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers. Physiological Reports. 2017. 5. 5. e13180
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Hideki Shirakawa, Takashi Kikuchi, Masahiko Ito. Calcium Signaling in Mammalian Eggs at Fertilization. CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2016. 16. 24. 2664-2676
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MISC (10):
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田中 嘉法, 田渕 絢香, 白川 英樹, 狩野 豊. In vivo環境下におけるマウス骨格筋ミトコンドリア内Ca2+動態の可視化-In vivo visualization of mitochondrial Ca2+ dynamics in mouse skeletal muscle during contractions. アグリバイオ = Agricultural biotechnology. 2024. 8. 1. 60-64
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田中 嘉法, 田渕 絢香, 白川 英樹, 狩野 豊. In vivo環境下におけるマウス骨格筋ミトコンドリア内Ca2+動態の可視化-In vivo visualization of mitochondrial Ca2+ dynamics in mouse skeletal muscle during contractions. 細胞. 2023. 55. 5. 335-338
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ITO MASAHIKO, SHIKANO TOMOHIDE, SHIRAKAWA HIDEKI, AWAJI TAKEO, MIYAZAKI SHUN'ICHI. 哺乳類卵活性化精子蛋白質候補ホスホリパーゼCゼータ細胞内動態および機能解析. 東京女子医科大学総合研究所紀要. 2007. 27. 21-22
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SHIRAKAWA HIDEKI, ITO MASAHIKO, MIYAZAKI SHUN'ICHI. FRET型プローブを用いた哺乳類卵細胞内IP3濃度変化の測定. 東京女子医科大学総合研究所紀要. 2006. 26. 20-21
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曽根 淑恵, 熊切 順, 武内 裕之, 木下 勝之, 伊藤 昌彦, 白川 英樹, 鹿野 朝秀, 宮崎 俊一. マウス胚初期発生におけるホスホリパーゼCゼーターの核移行. 日本不妊学会雑誌. 2005. 50. 4. 511-511
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Books (3):
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細胞内カルシウム実験プロトコール
羊土社 1996
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電子顕微鏡基礎技術と応用~物質のナノ局在解析~
学際企画 1994
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Biology of Germ Lines in Animals and Man
Japan Scientific Societies Press 1993
Lectures and oral presentations (80):
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Calcium-induced reorganization of cortical actin cytoskeleton in mammalian oocytes at fertilization
(2024)
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In vivo mitochondrial Ca<sup>2+</sup> dynamics during tetanic muscle contraction in male and female mice
(第100回日本生理学会大会 2023)
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Regulation of cortical actin dynamics and cytoplasmic flow by intracellular Ca<sup>2+</sup> in mouse oocytes
(第100回日本生理学会大会 2023)
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In vivo環境下における筋収縮負荷時のマウスミトコンドリア内Ca<sup>2+</sup>動態の可視化
(第76回日本体力医学会 2022)
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The organization and dynamics of cortical actin cytoskeleton regulated by cytosolic Ca<SUP>2+</SUP> in mammalian eggs.
(第99回日本生理学会合同大会 2022)
more...
Education (3):
- - 1991 The University of Tokyo Graduate School, Division of Science 動物学
- - 1989 University of Tsukuba Second Cluster of College 生物学類
- 1981 - 1984 私立武蔵高等学校
Professional career (2):
- 理学修士 (東京大学)
- 博士(医学) (東京女子医科大学)
Work history (5):
- 2010/04/01 - The University of Electro-Communications 准教授
- 2007/04/01 - 2010/03/31 電気通信大学 電気通信学部 准教授
- 2005/10/01 - 2007/03/31 The University of Electro-Communications Associate Professor
- 2002/07/01 - 2005/09/30 Tokyo Women's Medical University Assistant Professor
- 1991/04/01 - 2002/06/30 Tokyo Women's Medical University Instructor
Committee career (1):
Association Membership(s) (5):
日本生理学会
, 日本発生生物学会
, 日本生物物理学会
, Biophysical Society(アメリカ)
, 日本動物学会
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