Maiko Matsushita

マツシタマイコ | Maiko Matsushita

Affiliation and department：
Job title： Professor

Research field (4)： Other , Hematology and oncology , Internal medicine - General , Immunology

Research theme for competitive and other funds (6)：

2024 - 2027 去勢抵抗性前立腺癌に対する細胞外小胞スクリーニング法を用いた新規免疫増強薬の探索
2023 - 2025 なぜ骨髄腫は治癒しないのか、分子病態の解明とオートファジー創薬による克服
2018 - 2021 Development of novel combined immunotherapy using in silico screening system
2014 - 2017 Development of novel immunotherapy targeting leukemic stem cells.
2010 - 2011 Development of immunotherapy targeting melanoma stem cells.

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Papers (37)：

Maiko Matsushita, Sho Kashiwazaki, Satoshi Kamiko, Michio Kobori, Makoto Osada, Hisako Kunieda, Maki Hirao, Daiju Ichikawa, Yutaka Hattori. Immunomodulatory Effect of Proteasome Inhibitors via the Induction of Immunogenic Cell Death in Myeloma Cells. Pharmaceuticals. 2023. 16. 10. 1367-1367
Mikio Okayama, Kota Fujimori, Mariko Sato, Koichi Samata, Koki Kurita, Hiromu Sugiyama, Yutaka Suto, Genji Iwasaki, Taketo Yamada, Fumiyuki Kiuchi, et al. GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c-MET tyrosine kinase. Cancer medicine. 2023
Tateno S, Hirao M, Kikuchi T, Tsukada Y, Kunieda H, Osada M, Yamazaki K, Denda R, Hirose S, Matsushita M, et al. PAX5-positive plasma cell leukemia presenting as lymphocytosis. Rinsho Ketsueki. 2022. 63. 10. 1415-1420
Yutaka Hattori, Takumi Futo, Ryo Uozaki, Daiju Ichikawa, Takashi Yamaguchi, Tomofumi Yamamoto, Maiko Matsushita, Maki Hirao. Integrin β5 and β7 expression in lenalidomide-resistant multiple myeloma cells. International journal of hematology. 2022. 115. 4. 605-608
Matsushita M. Novel treatment strategies utilizing immune reactions against chronic myelogenous leukemia stem cells. Cancers. 2021. 13. 21. 5435

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MISC (27)：

服部豊, 松下麻衣子. 治療抗がん剤. 日本医師会雑誌. 2022. 151. 特別1. 125-130
Matsushita M. Immunogenic cell death in hematological malignancies. 臨床血液. 2021. 62. 7. 709-716
佐俣光一, 岡山幹夫, 岡山幹夫, 藤森宏太, 西山沙織, 辻宏樹, 不藤拓海, 市川大樹, 松下麻衣子, 岩崎源司, et al. 天然物由来成分komaroviquinone及びその誘導体群はin vivoにおいて抗骨髄腫活性を示す. Pharmaco-Hematologyシンポジウム講演要旨集. 2019. 20th
Sho Kashiwazaki, Satoshi Kamiko, Ryo Uozaki, Tomofumi Yamamoto, Daiju Ichikawa, Yutaka Hattori, Maiko Matsushita, Maki Hirao, Hisako Kunieda, Kohei Yamazaki. Immunomodulatory Effects of Proteasome Inhibitors in Multiple Myeloma. BLOOD. 2018. 132
Ryo Uozaki, Shuji Aida, Takasi Yamagughi, Tomofumi Yamamoto, Sho Kashiwazaki, Hiroshi Yanagawa, Daiju Ichikawa, Maiko Matsushita, Yutaka Hattori. Elucidation of the IMiDS-Resistant Mechanism and Development of the Overcoming Drugs Inducing CRBN Independent G2/M Cell Cycle Arrest in Myeloma Cells. BLOOD. 2018. 132

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Patents (5)：

Books (2)：

Lectures and oral presentations (100)：

多発性骨髄腫に対して免疫原性細胞死を誘導する天然物由来化合物の安全性と有効性の検討
(第48回日本骨髄腫学会学術集会 2023)
エピジェネティック因子CDYL2は多発性骨髄腫におけるレナリドミド感受性を減弱する
(第48回日本骨髄腫学会学術集会)
エピゲネティック因子CDYL2は多発性骨髄腫におけるレナリドミド耐性に関連する
(日本薬学会第143年会 2023)
Drug repositioning revealed ambroxol induced myeloma cell death by inhibiting autophagy.
(第84回日本血液学会学術総会 2022)
Development of komaroviquinone-derivatives that induce immune cell death of multiple myeloma.
(第84回日本血液学会学術総会 2022)

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Education (2)：

Professional career (1)：

Work history (5)：

Awards (2)：

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