Rchr
J-GLOBAL ID:200901021917424212   Update date: Jul. 20, 2024

Hosoyamada Makoto

ホソヤマダ マコト | Hosoyamada Makoto
Affiliation and department:
Job title: Professor
Research field  (3): Nephrology ,  Pharmacology ,  Clinical pharmacy
Research keywords  (6): 病態生理 ,  尿酸 ,  腎臓 ,  pathophysiology ,  urate ,  kidney
Research theme for competitive and other funds  (38):
  • 2022 - 2025 Elucidation of the mechanism of exercise-induced acute kidney injury associated with renal hypouricemia type 1 model mice
  • 2018 - 2022 Sutudy for substances responsible for renal failure death in xanthine oxidoreductase knockout mice
  • 2017 - 2020 Generation of human urate metabolism complete model mice by suppressing xanthine dehydrogenase expression
  • 2014 - 2017 Analysis of genes influencing serum urate levels
  • 2014 - 2017 Studies on androgenic and angiotensin system inhibitors for inhibiting the progression of chronic kidney disease
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Papers (120):
  • Masaru Doshi, Yujin Natori, Akira Ishii, Daisuke Saigusa, Shiro Watanabe, Makoto Hosoyamada, Yutaka Hirashima-Akae. Hypothermia increases adenosine monophosphate and xanthosine monophosphate levels in the mouse hippocampus, preventing their reduction by global cerebral ischemia. Scientific reports. 2024. 14. 1. 3187-3187
  • 藤井 航, 浅川 信一郎, 山崎 修, 田村 好古, 藤垣 嘉秀, 細山田 真, 柴田 茂. リン酸化によるURAT1の制御機構の解明とメタボリックシンドロームに合併する尿酸代謝異常への関与の検討. 日本痛風・尿酸核酸学会総会プログラム・抄録集. 2024. 57回. 62-62
  • Yu Toyoda, Hiroshi Miyata, Naohiro Uchida, Keito Morimoto, Ryuichiro Shigesawa, Hidetoshi Kassai, Kazuki Nakao, Naoko H Tomioka, Hirotaka Matsuo, Kimiyoshi Ichida, et al. Vitamin C transporter SVCT1 serves a physiological role as a urate importer: functional analyses and in vivo investigations. Pflugers Archiv : European journal of physiology. 2023
  • Hisayo Yamaoka, Keiko Yamaoka, Shigekazu Watanabe, Hideyuki Tanaka, Makoto Hosoyamada, Yuzo Komuro. Lactose Stabilization Prolongs In Vivo Retention of Cross-linked Fish Collagen Subcutaneous Grafts in Nude Mice. Plastic and reconstructive surgery. Global open. 2022. 10. 10. e4601
  • 道志 勝, 渡辺 志朗, 名取 雄人, 細山田 真, 赤江 豊. 甲状腺ホルモン投与がマウス脳虚血再灌流後の海馬TGF-β1遺伝子発現に及ぼす影響. 日本薬学会年会要旨集. 2022. 142年会. 28PO8-12
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MISC (409):
  • 道志勝, 名取雄人, 石井晃, 三枝大輔, 渡辺志朗, 細山田真, 赤江豊. Effect of hypothermia on the changes in the levels of metabolites in the mouse hippocampus caused by cerebral ischemia. 日本薬学会年会要旨集(Web). 2024. 144th
  • 道志勝, 名取雄人, 石井晃, 渡辺志朗, 細山田真, 赤江豊. Metabolome analysis of hippocampus and serum in mouse model of cerebral ischmeia. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 河野 肇, 木村 佳貴, 津久井 大輔, 細山田 真. 痛風・高尿酸血症の病態 動脈硬化における尿酸のインフラマソーム活性化を介した役割. 痛風と尿酸・核酸. 2021. 45. 1. 94-94
  • 河野 肇, 木村 佳貴, 津久井 大輔, 細山田 真. 痛風・高尿酸血症の病態 動脈硬化における尿酸のインフラマソーム活性化を介した役割. 日本痛風・尿酸核酸学会総会プログラム・抄録集. 2021. 54回. 44-44
  • 道志勝, 渡辺志朗, 名取雄人, 細山田真, 赤江豊. Triiodothyronine aggravates delayed neuronal death caused by transient cerebral ischemia in mice. 日本薬学会年会要旨集(Web). 2021. 141st
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Patents (2):
Books (2):
  • 薬学生のための新臨床医学-症候および疾患とその治療
    広川書店 2009 ISBN:4567497902
  • Potassium-Retaining Diuretics : Aldosteron antagonists. In Diuretics : Handbook of Experimental Pharmacology. (共著)
    Greger RF. Knauf H. Mutschler E. Springer 1995
Education (2):
  • 1992 - 1996 The University of Tokyo Post-graduate School of Medicine
  • - 1990 The University of Tokyo Faculty of Medicine School of Medicine
Professional career (1):
  • PhD. (The University of Tokyo)
Work history (6):
  • 2011 - 現在 Teikyo University Faculty of Pharma-Science Professor
  • 2008 - 2011 Keio University Faculty of Pharmacy Associate Professor
  • 2007 - 2008 Kyoritsu University of Pharmacy Associate Professor
  • 2005 - 2007 Kyoritsu University of Pharmacy Associate Professor
  • 2001 - 2005 Kyorin University Faculty of Medicine Lecturer
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Committee career (2):
  • 2002 - 2005 The Japanese Pharmacological Society councilman
  • 2003 - Japanese Society of Gout and Nucleic Acid metabolism councilman
Awards (1):
  • 2017/02 - 日本痛風·核酸代謝学会 日本痛風・核酸代謝学会賞
Association Membership(s) (8):
THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本痛風・核酸代謝学会 ,  日本薬理学会 ,  日本腎臓学会 ,  The Japanese Society of Nephrology ,  Japanese Society of Gout and Nucleic Acid metabolism ,  The Japanese Pharmacological Society
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