Rchr
J-GLOBAL ID：200901022802678128
Update date: Oct. 08, 2024
Suhara Tetsuya
スハラ テツヤ | Suhara Tetsuya
Affiliation and department：
Job title：
Deputy Executive Director
Homepage URL (1)：
http://web.nirs.qst.go.jp/
Research field (1)：
Psychiatry
Research keywords (8)：
quantum life science
, Tau imaging
, トランスポーター
, 神経伝達物質受容体
, PET
, Transportor
, Neurotransmitter receptor
, PET
Research theme for competitive and other funds (45)：
- 2017 - 2020 Evaluation of tau accumulation with PBB3-PET in amyloid negative dementia patients
- 2016 - 2019 Evaluation of tau protein related neural dysfunction: PET and 3T MRS study
- 2014 - 2018 Tau PET study for revealing the pathogenesis and establishing the objective marker of disease severity in neurodegenerative dementia
- 2014 - 2018 Evaluation of tau accumulation with PBB3-PET in amyloid negative dementia patients
- 2011 - 2016 Neural basis of intuitive and deliberative decision-making impairments in neuropsychiatric disorders
- 2011 - 2016 Molecular imaging of neurotoxic signaling in neurodegenerative disorders
- 2011 - 2013 Neuromolecular imaging study of internet addiction
- 2010 - 2012 Developing a new diagnostic system using positron emission tomography for dementia with Lewy bodies
- 2009 - 2011 Neural network development disorder as a cause of cognitive/behavioral impairment in childhood. mental function and neural stem cell transplantation
- 2008 - 2011 アミロイドイメージングを用いたアルツハイマー病の発症・進展予測法の実用化に関する多施設大規模臨床研究
- 2008 - 2010 Normal database of the serotonergic neurotransmission system in living human brain as measured positron emission tomography
- 2007 - 2010 Molecular imaging of altered dopamine transmission in patients with schizophrenia
- 2007 - 2009 Research on substance P receptor as a novel target for antidepressant therapy using neuroimaging techniques
- 2007 - 2009 The mechanism for fear learning concerning NMDA receptor NR2B subunit.
- 2007 - 2008 Role of dopamine in metamemory investigated by fMRI and PET
- 2006 - 2007 Construction of Normal Database of Neurotransmission System in the Human Brain using Positron emission tomography
- 2005 - 2007 Brain portrait research on the biological factor of the suicide attempt in persons-of-middle-or-advanced-age depression
- 2005 - 2006 Experimental use of positron emission tomography to analyze the damage of neuronal circuit and its restration with cell transplantation therapy.
- 2005 - 2006 Biological mechanisms of pubertal onset of schizophrenia in animal model of rats based on neurodevelopmental hypothesis.
- 2005 - 2006 抽象的認知能力の脳機能局在と機能分子イメージング
- 2004 - 2006 INVESTIGATION OF THE NEUROCHEMICAL MECHANISM UNDERLYING DRUG ADDICTION USING IN VIVO PET IMAGING
- 2004 - 2006 A study on tachykininergic neurotransmission in the primate central nervous system aimed at developing novel drugs against mood disorders
- 2004 - 2006 地域精神医療と芸術表現に関する総合的研究
- 2003 - 2006 Morphological and functional neuroimaging studies on progressive changes in schizophrenia.
- 2004 - 2005 In-vivo quantification analysis of activated microglia in the brain of dementia
- 2004 - 2005 The utility and mechanisms of action of repetitive transcranial magnetic stimulation in depression
- 2004 - 2005 Experimental analysis of neuronal conduction by neurogenerative treatment using PET neurorecepter imaging and optical imaging.
- 2002 - 2005 神経伝達機能 イメージングを用いた精神疾患の診断法および治療効果の客観手評価法の確立に関する研究
- 2002 - 2005 PETによる気分障害患者の 病態と治療法の作用機序に関する研究
- 2002 - 2003 脳イメージングのためのリガンド輸送ツール開発
- 2002 - 2003 The role of serotonin transporter during neurodevelopment in the formation of biological vulnerability to depression
- 2001 - 2002 PET study of 5-HT1A and GABA receptors in temporal lobe epilepsy.
- 1997 - 2002 精神分裂病における神経伝達の異常
- 2000 - 2001 Animal model of schigophrenia based on the suppression of ganes in postnatal brain
- 1999 - 2001 Development of a quantitative diagnostic method of ^<19>F drug metabolism using clinical MRI
- 1999 - 2001 The development and evaluation of super high resolution MR microscopy.
- 1999 - 2000 10テスラ近傍の超高磁場MRIの臨床利用に関する可能性と意義に関する実験的研究
- 1998 - 2000 New radioligand for functional imaging of human brain 5-HT1A receptors
- 1998 - 1999 Development of animal model of schizophrenia based on prenatal brain injuries
- 1997 - 1999 The research of the cerebral serotonin transporter and Receptor in affective disorder with positron emission tomography
- 1997 - 1998 receptor studies on schizophrenia
- 1995 - 1996 PET receptor studies on scgizophrenia and extrapyramidal side effects.
- 1991 - 1992 Research on Brain Function through in vivo Neuroreceptor Study Using Positron Emission Tomography
- 1990 - 1990 躁うつ病の脳内受容体のポジトロンCTによる研究
- Research for the abnormality of neuro transmission in psychiatric disorders.
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Papers (452)：
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Toshiyuki Hirabayashi, Yuji Nagai, Yuki Hori, Yukiko Hori, Kei Oyama, Koki Mimura, Naohisa Miyakawa, Haruhiko Iwaoki, Ken-Ichi Inoue, Tetsuya Suhara, et al. Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates. Nature communications. 2024. 15. 1. 5369-5369
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Hiroyuki Morino, Takashi Kurashige, Yukiko Matsuda, Maiko Ono, Naruhiko Sahara, Tomohiro Miyasaka, Yoshiyuki Soeda, Hitoshi Shimada, Yu Yamazaki, Tetsuya Takahashi, et al. Clinical and Pathological Features of FTDP-17 with MAPT p.K298_H299insQ Mutation. Movement disorders clinical practice. 2024
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Yukiko Hori, Koki Mimura, Yuji Nagai, Yuki Hori, Katsushi Kumata, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuchi, Takafumi Minamimoto. Reduced serotonergic transmission alters sensitivity to cost and reward via 5-HT1A and 5-HT1B receptors in monkeys. PLoS biology. 2024. 22. 1. e3002445
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Soichiro Kitamura, Yasuyuki Kimura, Keisuke Takahata, Sho Moriguchi, Manabu Kubota, Hitoshi Shimada, Hironobu Endo, Yuhei Takado, Kazunori Kawamura, Ming-Rong Zhang, et al. Serotonergic Neurotransmission in Limbic Regions May Reflect Therapeutic Response of Depressive Patients: A PET Study With 11C-WAY-100635 and 18F-MPPF. The international journal of neuropsychopharmacology. 2023. 26. 7. 474-482
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Masaki Oya, Kiwamu Matsuoka, Manabu Kubota, Junya Fujino, Shisei Tei, Keisuke Takahata, Kenji Tagai, Yasuharu Yamamoto, Hitoshi Shimada, Chie Seki, et al. Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism. Scientific Reports. 2023. 13. 1
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MISC (315)：
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平田 浩聖, 松岡 究, 遠藤 浩信, 互 健二, 小久保 奈緒美, 篠遠 仁, 高畑 圭輔, 小野 麻衣子, 河村 和紀, 張 明栄, et al. 進行性核上性麻痺患者におけるアストロサイト活性度の評価. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2022. 16回. 84-84
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木村泰之, 木村泰之, 山田真希子, 島崎聡立, 西野いずみ, 張明栄, 樋口真人, 須原哲也. ヒスタミンH3レセプターのPETイメージング. 応用薬理. 2022. 102. 5-6
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松岡究, 松岡究, 高堂裕平, 互健二, 久保田学, 久保田学, 佐野康徳, 高畑圭輔, 小野麻衣子, 関千江, et al. The associations of apathy with tau depositions and oxidative stress in progressive supranuclear palsy. 日本生物学的精神医学会(Web). 2022. 44th
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中野高志, 中野高志, 高村真広, 西村春輝, 町澤まろ, 市川奈穂, 岡本泰昌, 山脇成人, 山田真希子, 須原哲也, et al. Resting-state brain activity predicts neurofeedback training aptitude. 人工知能学会全国大会論文集(Web). 2022. 36th
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高橋真奈美, 高橋真奈美, 田桑弘之, 田桑弘之, 漆畑拓弥, 下條雅文, 折原あすみ, 小野麻衣子, 高堂祐平, 冨田裕, et al. 生体脳イメージングを用いたタウ凝集体を有する神経細胞の脳外排出メカニズムの実証. 脳循環代謝(Web). 2021. 33. 1
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Books (2)：
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脳の形態と機能ー画像医学の進歩
振興医学出版社 2005
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7.脳機能画像から見た認知機能
新世紀の精神科治療学 第6巻認知の科学と臨床、 中山書店 2003
Education (2)：
- - 1984 Jikei University Faculty of Medicine
- - 1984 Jikei University Faculty of Medicine
Professional career (1)：
- Doctor of Medical Sciences (Jikei University School of Medicine)
Work history (36)：
- 2024/04 - 現在 National Institutes for Quantum Science and Technology Deputy Executive Director
- 2023/04 - 2024/03 National Institute of Radiological Sciences Quantum Life and Medical Science Directorate Managing Director
- 2021/04 - 2023/03 National Institute for Quantum Science and Technology Institute for Quantum Life Science Deputy Director General
- 2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology
- 2016/04 - 2019/03 National Institutes for Quantum and Radiological Science and Technology
- 2011/04 - National Institute of Radiological Sciences, Molecular Imaging Center, Molecularneuroimaging Program Program Director
- 2005/11 - :独立行政法人放射線医学総合研究所分子イメージング研究センター分子神経イメージング研究グループグループリーダー
- 2005 - : Group Director, Department of Molecular Neuroimaging, Molecular Imaging Center
- 2002 - :独立行政法人放射線医学総合研究所脳機能イメージング研究開発推進室室長
- 2001 - :独立行政法人放射線医学総合研究所特別上席研究員
- 2001 - : Director of special Research of Brain Imaging,
- 1997 - :科学技術振興事業団戦略基礎研究研究代表者
- 1997 - : Research Director of CREST Project (Japan Science
- 1996 - :科学技術庁放射線医学総合研究所高度診断機能ステーション
- 1996 - : Senior Researcher, Div. of Advanced Technology for
- 1993 - :科学技術庁放射線医学総合研究所臨床研究部主任研究官
- 1992 - :スウェーデン.カロリンスカ研究所精神医学教室客員研究員
- 1992 - :科学技術庁放射線医学総合研究所臨床研究部主任研究官
- 1992 - : Visiting Scientist at Dep. of Clinical Neuroscience
- 1992 - : Senior Researcher, Div. of Clinical Research,
- 1989 - :科学技術庁放射線医学総合研究所臨床研究部研究員
- 1989 - : Researcher, Div. of Clinical Research, National
- 1986 - :東京慈恵会医科大学精神医学教室医員
- 1986 - : Medical Staff in Psychiatry, Jikei University
- 1984 - :国立病院医療センター研修医
- 1984 - : Resident in Internal Medicine and Psychiatry,
- 主任研究官
- National Institute of Radiological Sciences
- and Technology Corp.)
- Sciences
- Medical Imaging, National Institute of Radiological
- Hospital, Stockholm, Sweden
- Psychiatry and Psychology Section, Karolinska
- Institute of Radiological Sciences
- Hospital
- National Medical Center Hospital
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Awards (8)：
- 2018/04 - 平成30年度文部科学大臣表彰科学技術賞
- 2012/01 - 第4回分子イメージング賞
- 2009 - ベルツ賞一等賞
- 2000 - 科学技術庁官業績表彰
- 1998 - 第36回日本核医学会賞
- 1984 - 第92回東京慈恵会医科大学臨床賞
- Award of The Japanese Society of Nuclear Medicine (1989)
- Award of Clinical Medicine (1984)
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Association Membership(s) (12)：
日本生物学的精神医学会
, 日本神経精神薬理学会
, 日本神経科学学会
, 日本核医学会
, 生物学的精神医学会
, 国際神経精神薬理学会
, The Japanese Society of Neuropsychopharmacology
, Society of Nuclear Medicine
, Japanese Society of Nuclear Medicine
, Japanese Society of Biological Psychiatry
, Japan Neuroscience Society
, Collegium International Neuro-Psychopharmacologium
