OHSUGI Miho

オオスギミホ | OHSUGI Miho

Affiliation and department：
Job title： Professor
Homepage URL (2)： http://park.itc.u-tokyo.ac.jp/ohsugilab2013/ , http://www.sysbio.jst.go.jp/e/sakigake3/saki_03.html

Research field (3)： Developmental biology , Cell biology , Molecular biology

Research keywords (9)： Centrosome , Preimplantation embryo , Nuclear formation , Zygote , 紡錘体形成 , 染色体分配 , mitosis , Mitotic chromosome dynamics , Spindle formation

Research theme for competitive and other funds (21)：

2022 - 2024 マウス卵割期胚発生におけるゲノム倍数性、細胞の大きさ、両者のバランスの重要性
2020 - 2023 受精卵への雌性ゲノム継承を保証する哺乳類特有の制御機構
2020 - 2022 核内クロマチン密度に着目した全能性獲得の場としての核構造解析
2018 - 2021 Improving the production efficiency of mammalian haploid cells by controlling nuclear DNA density
2015 - 2020 3D architecture of mitotic chromosomes

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Papers (41)：

Yoshihiro Kawasaki, Tomoko Hamaji, Koji Owada, Akiko Hayashi, Yuping Wu, Taisaku Nogi, Miwa Okada, Yuta Kouyama, Atsushi Niida, Koshi Mimori, et al. APC mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness. 2020
Takaya Totsuka, Miho Ohsugi. Production of mouse androgenetic embryos using spindle perturbation. Scientific Reports. 2020. 10. 1
Shou Soeda, Shou Soeda, Kaori Yamada-Nomoto, Kaori Yamada-Nomoto, Tatsuo Michiue, Miho Ohsugi. RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability. Developmental Cell. 2018. 47. 3. 363-376
Keishi Shintomi, Fukashi Inoue, Hiroshi Watanabe, Keita Ohsumi, Miho Ohsugi, Tatsuya Hirano. Mitotic chromosome assembly despite nucleosome depletion in Xenopus egg extracts. SCIENCE. 2017. 356. 6344. 1284-1287
Shou Soeda, Kaori Yamada-Nomoto, Miho Ohsugi. The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase. JOURNAL OF CELL SCIENCE. 2016. 129. 19. 3609-3619

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MISC (21)：

Miho Ohsugi, Hiroshi Watanabe. Pronuclear size control in mouse zygotes. GENES & GENETIC SYSTEMS. 2016. 91. 6. 334-334
N. Tokai-Nishizumi, M. Ohsugi, T. Yamamoto. Tropomyosin 4, actin binding protein, contributes to the proper spindle orientation during mitosis and meiosis. MOLECULAR BIOLOGY OF THE CELL. 2011. 22
家村顕自, 押森直木, 山本雅, 大杉美穂. 細胞分裂・DNA修復 AMPKγは分裂期における染色体整列に寄与する(Cell division and DNA repair AMPKγ is required for chromosome alignment during mitosis). 日本細胞生物学会大会講演要旨集. 2010. 62回. 125-125
大杉美穂, 足立健次郎, 宝来玲子, 角田茂, 須藤カツ子, 相良洋, 渡海紀子, 住, 岩倉洋一郎, 山本雅. 細胞周期と発がんクロモキネシンKidによる核膜形成制御(Cell Cycle and Tumorigenesis Kid-Mediated Anaphase Chromosome Compaction Safeguards Mouse Early Embryos Against Multinuclear Formation). 日本癌学会総会記事. 2008. 67回. 45-45
Miho Ohsugi, Naoki Oshimori. The mechanisms of spindle pole formation for the proper chromosome segregation. Seikagaku. 2008. 80. 3. 210-214

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Education (2)：

The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry

Professional career (1)：

Ph.D. (The University of Tokyo)

Association Membership(s) (4)：

The American Society for Cell Biology , JAPAN SOCIETY FOR OVA RESEARCH , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR CELL BIOLOGY

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