Research keywords (4):
臨床薬理
, 薬物代謝
, Clinical Pharmacology
, Drug Metabolism
Research theme for competitive and other funds (17):
2021 - 2024 がん患者における健康食品と医薬品併用の安全性に関する研究
2016 - 2019 Research for safe use of herbal supplements -investigation of the adverse effects of combined use with medicines
2012 - 2015 The appropriate use of OTC drugs in multiple medication.
2011 - 2013 Educational effects of 6 years of consistent educational programs to train medical professions for a team-based medical care
2010 - 2012 Association between genetic polymorphisms of drug-metabolizingenzymes and factors of liver cancer
2000 - 2001 Evaluation of Drug-metabolizing enzyme activity and-drug interaction in paitients with hepatic disease
1999 - 2000 Evaluation of reliability of human liver surgical samples from hepatocellular carcinoma and metastatic cancer patients on the application to the drug-metabolism study
1997 - 2000 Evaluation of pharmacodynamics of drugs acting on the central nervous system using computer-assisted eye movement analysis.
1998 - 1999 Study of the effects of antineoplastic agents on drug metabolizing enzymes and evaluation of its efficacy and safety
1996 - 1997 Polymorphism of drug-metabolising enzymes
1994 - 1995 Polymorphism of drug-metabolyzing enzymes and the assessment of drug efficacy and safety
薬物代謝の遺伝多型
慢性腎不全の薬物代謝酵素に対する影響
マイクロダイアリシス法による薬物動態の検討
Polymorphic drugmetabolism
Effect of Chronic renan failure status on drug-metabolyzing enzymes
Assessment of Plurmacokinetics employing the Microdialysis method
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Papers (46):
Koichiro Shinya, Yuki Nishimura, Kakei Ryu, Takehiko Sambe, Masaya Fujishiro, Akihiro Nakauchi, Yumika Kashiwabuchi, Mariko Iwase, Hirokazu Chokki, Norimitsu Kurata, et al. Short-term administration of Polypodium leucotomos extract does not inhibit CYP3A4-mediated metabolism of midazolam in healthy subjects: an open-label, two-period, fixed-sequence study. International journal of dermatology. 2022
Hirokazu Chokki, Yuki Nishimura, Mariko Iwase, Norimitsu Kurata, Koichiro Shinya, Mayumi Tsuji, Masafumi Ito, Mutsumi Asai, Hirofumi Morino, Takanori Miura, et al. Lack of inhibitory effect of wood creosote on cytochrome <scp>P450-mediated</scp> drug metabolism. Traditional & Kampo Medicine. 2022. 9. 1. 3-9
Yumika Kashiwabuchi, Yuki Nishimura, Norimitsu Kurata, Mariko Iwase, Yuji Kiuchi, Koji Nobe. Inhibition of CYP3A-mediated Midazolam Metabolism by <i>Kaempferia Parviflora</i>. Food Safety. 2022. 10. 1. 32-41