Aruga Jun

アルガジュン | Aruga Jun

Affiliation and department：
Homepage URL (2)： http://www.med.nagasaki-u.ac.jp/phrmch1/ , http://www.med.nagasaki-u.ac.jp/phrmch1/eng/eng-index.html

Research field (3)： Neuroscience - general , Pharmacology , Evolutionary biology

Research keywords (9)： Monoaminergic Nervous System , Obsessive-Compulsive Spectrum Disorders , Mood Disorders , Attention-Deficit Hyperactivity Disorders , Disease Model Animals , LRR transmembrane proteins , Zic Family Proteins , Neural Development , Evolution of the Nervous System

Research theme for competitive and other funds (41)：

2022 - 2025 LRR膜タンパク質によるセロトニン性神経系の発達制御の破綻による病態の解明
2024 - 2025 Regulation of the Monoaminergic Nervous System by LRR Membrane Proteins and the Pathophysiology of Mood Disorders and Obsessive-Compulsive Spectrum Disorders
2023 - 2024 Investigating the Pathophysiological Role of Slitrk Proteins in the Regulation of the Monoaminergic Nervous System
2020 - 2022 How are synaptic adhesion molecules involved in functional gastrointestinal disorders?
2019 - 2022 Mechanism underlying the regulation of diffuse transmission by LRR transmembrane proteins

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Papers (159)：

Yoshifumi Matsumoto, Hideki Miwa, Kei-Ichi Katayama, Arata Watanabe, Kazuyuki Yamada, Takashi Ito, Shinsuke Nakagawa, Jun Aruga. Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala. Frontiers in Molecular Neuroscience. 2024. 17. 1386924-1386924
Stephanie Efthymiou, Wenyan Han, Muhammad Ilyas, Jun Li, Yichao Yu, Marcello Scala, Nancy T Malintan, Muhammad Ilyas, Nikoleta Vavouraki, Kshitij Mankad, et al. Human mutations in SLITRK3 implicated in GABAergic synapse development in mice. Frontiers in Molecular Neuroscience. 2024. 17. 1222935-1222935
Minoru Hatayama, Kei-Ichi Katayama, Yukie Kawahara, Hayato Matsunaga, Noriko Takashima, Yoshimi Iwayama, Yoshifumi Matsumoto, Akinori Nishi, Takeo Yoshikawa, Jun Aruga. SLITRK1-mediated noradrenergic projection suppression in the neonatal prefrontal cortex. Communications Biology. 2022. 5. 1. 935-935
Kei-Ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G Ornthanalai, Hayato Matsunaga, Wakako Fujita, Yoshifumi Matsumoto, Takumi Akagi, et al. Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation. iScience. 2022. 25. 7. 104604-104604
Misato Ichise, Kazuto Sakoori, Kei-ichi Katayama, Naoko Morimura, Kazuyuki Yamada, Hiroki Ozawa, Hayato Matsunaga, Minoru Hatayama, Jun Aruga. Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics. Frontiers in Molecular Neuroscience. 2022. 15

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MISC (26)：

牧野まどか, 富岡直子, 松永隼人, 有賀純, 有賀純. 神経膜タンパク質Elfn2による消化管機能制御. 日本薬理学雑誌. 2020. 155. Supplement
ICHISE Misato, HATAYAMA Minoru, ARUGA Jun. 線条体ニューロンにおけるLrtm2の役割. 日本神経化学会大会抄録集(Web). 2019. 62nd
牧野まどか, 冨岡直子, 松永隼人, 有賀純, 有賀純. Elfn2欠損マウスに見られる代謝異常症. 日本薬理学雑誌. 2018. 151. Supplement
ICHISE Misato, KATAYAMA Kei-ichi, SAKOORI Kazuto, MORIMURA Naoko, HATAYAMA Minoru, HATAYAMA Minoru, ARUGA Jun, ARUGA Jun. マウスの探索行動とモノアミン代謝に関与するLrtm2タンパク質の分子機能. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th
有賀純, 有賀純, 富岡直子, 安田浩樹. Elfnファミリータンパク質による代謝共役型グルタミン酸受容体のトランスシナプス制御. 日本薬理学会西南部会プログラム/抄録集. 2015. 68th. 43

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Books (1)：

Zic Family : Evolution, Development and Disease
Springer 2018 ISBN:9789811073106

Professional career (1)：

医学博士 (東北大学大学院)

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