Wakamori Minoru

ワカモリミノル | Wakamori Minoru

Affiliation and department：

Research field (4)： Oral medicine , Clinical pharmacy , Physiology , Neuroscience - general

Research keywords (8)：歯科薬理学 , 分子薬理学 , 口腔生理学 , 神経生理学 , 分子細胞生理学 , Orofacial physiology , Neurophysiology , Molecular & Cellular Physiology

Research theme for competitive and other funds (25)：

2021 - 2025 唾液腺発生における神経-器官相互作用の分子機構の解明と機能再生技術への応用
2021 - 2024 エピプロフィンによる上皮間葉転換制御機構を応用したがん治療と器官原器複製術の開発
2020 - 2023 臨床ゲノム研究に基づく非興奮性細胞における電位依存性カルシウムチャネル機能の解明
2015 - 2018 The development of light-activatable proteins for inducing mechanical stimulation in the cells
2015 - 2018 Pathophysiological analysis of oral diseases caused by dysregulation of cation channels

2014 - 2017 Exploring the regulatory mechanism of hypothalamic local circuitry using a mouse line for visualizing CRF neurons by a fluorescent protein

2013 - 2015 Drug-delivery-system through ion channels

2011 - 2013 An investigation of the relationship between occlusion, mastication and mental activity using in vivo patch clamp recording method

2010 - 2012 NETWORK ANALYSIS AMONG HARD TISSUE CELLS USING MULTI-PHOTON MICROSCOPE

2009 - 2011 Functional analysis of oral sensation on the basis of signalplexes

2009 - 2011 Mechanism of sensory dysfunction of swallowing in elderly people and its applied regenerative therapy

2008 - 2009 味覚形成における脂質ミクロドメインの役割

2005 - 2009 Ca^<2+> channelplexes : assembly in the membrane and physiological significance

2006 - 2007 優性及び劣性遺伝形態をとる運動失調症マウスの小脳機能の電気生理学的比較

2005 - 2005 小脳失調症の遺伝子、分子、細胞、小脳回路と多次元コンピュテーショナル神経科学

2003 - 2004 Elecrtophysiological properties of voltage-gated Ca^<2+> channel and other cation channels.

2001 - 2002 Functional relationship between Ca^<2+>-dependent cation channel and Ca^<2+>-permeable channel

1999 - 2000 Dynamic analysis of subcellular ionic signalling in neurons

1999 - 2000 Electrophysiological study of mutant P-type Ca^<2+> channels causing diseases

1997 - 1998 Study of electrophysiological properties of cloned N-type Ca^<2+> channel

1997 - 1998 Production & analysis of Ca^<2+> channel subunit-defecient mice.

電位依存性カルシウムチャネルの分子神経生理学的研究

カルシウム透過型カチオンチャネルの分子神経生理学的研究

Molecular and neurophysiological study on voltage-dependent Calcium Channel

Molecular and neurophysiological Study on Calcium permeable Cation Channels

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Papers (68)：

Kaori Takahashi, Takashi Yoshida, Minoru Wakamori. Periodontal Ligaments Enhance Neurite Outgrowth in Trigeminal Ganglion Neurons through Wnt5a Production Induced by Mechanical Stimulation. American Journal of Physiology-Cell Physiology. 2022. 323. 6. C1704-C1719
真藤裕基, 若森実, 中井淳一, 中村卓史. 副交感神経から分泌されるアセチルコリン(ACh)が、唾液腺の発生過程で筋上皮細胞の分化誘導と機能的器官内配置を決定している(Acetylcholine(ACh), a parasympathetic neurotransmitter, orchestrates the induction and the positioning of myoepithelial cells in developing salivary glands). Journal of Oral Biosciences Supplement. 2022. 2022. 250-250
Yuki Shindo, Hannah M. Nakamura, Junichi Nakai, Minoru Wakamori, Takashi Nakamura. A parasympathetic neurotransmitter induces myoepithelial cell differentiation during salivary gland development. Experimental Cell Research. 2022. 416. 1. 113137-113137
Chenyao Wang, Shin-ichiro Horigane, Minoru Wakamori, Shuhei Ueda, Takeshi Kawabata, Hajime Fujii, Itaru Kushima, Hiroki Kimura, Kanako Ishizuka, Yukako Nakamura, et al. Identification of ultra-rare disruptive variants in voltage-gated calcium channel-encoding genes in Japanese samples of schizophrenia and autism spectrum disorder. Translational Psychiatry. 2022. 12. 1. 84-84
Kaori Takahashi, Takashi Yoshida, Minoru Wakamori. Mode-selective inhibitory effects of eugenol on the mouse TRPV1 channel. Biochemical and biophysical research communications. 2021. 556. 156-162

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MISC (121)：

塚本匡顕, 千葉雪絵, 若森実, 日高將文, 山田智士, 角替俊輔, 長由扶子, 榊原良, 今津拓也, 所聖太, et al. Inhibition of Voltage-gated Sodium Channel Subtypes (Na_v1.1-Na_v1.7) by Tetrodotoxin Analogues. 天然有機化合物討論会講演要旨集(Web). 2018. 60th
Takashi Yoshida, Kaori Takahashi, Minoru Wakamori. The inhibitory mechanism of eugenol on TRPV1 channel. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 175P-175P
相川知徳, 宮崎太輔, 三國貴康, 重本隆一, 若森実, 狩野方伸, 渡邊雅彦, 水澤英洋, 渡瀬啓. Cav2.1カルボキシル末端細胞質内ドメインの病態生理学的意義の検討. 臨床神経学. 2013. 53. 12. 1495-1495
Takashi Yoshida, Kaori Takahashi, Takashi Kikuchi, Minoru Wakamori. The inhibitory mechanism of eugenol on TRPV1 channel. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 171P-171P
若森実, 三木崇史, 中尾章人, 高田宜則, 森泰生. 電位依存性チャネル. 脳神経科学イラストレイテッド改訂第3版. 2013

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Professional career (1)：

(BLANK) (Tohoku University)

Work history (10)：

2020/04 - 現在 Tohoku University Graduate School of Dentistry Professor
2007/04 - 2020/03 Tohoku University Graduate School of Dentistry
2004/04 - 2007/03 Kyoto University Graduate School of Engineering, Department of Synthetic Chemistry and Biological Chemistry
2002/04 - 2005/03 岡崎国立共同研究機構生理学研究所生体情報研究系情報記憶研究部門(客員部門) 客員准教授
2003/04 - 2004/03 Kagoshima University Graduate School of Medical and Dental Sciences

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Association Membership(s) (4)：

JAPANESE DENTAL EDUCATION ASSOCIATION , 北米神経科学会 , JAPANESE ASSOCIATION FOR ORAL BIOLOGY , THE JAPANESE PHARMACOLOGICAL SOCIETY

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