Rchr
J-GLOBAL ID：200901024571319432   Update date: Nov. 02, 2023

KIMATA-ARIGA Yoko

KIMATA-ARIGA Yoko
Affiliation and department：
Yamaguchi University Faculty of Agriculture Biological Chemistry

About Yamaguchi University Faculty of Agriculture Biological Chemistry


Job title： Professor
Homepage URL  (1)： https://www.yamaguchi-u.ac.jp/agr/teachers/index.html
Research field  (1)： Functional biochemistry
Research keywords  (3)： 生体分子科学 ,  光合成 ,  plant physiology
Research theme for competitive and other funds  (13)：
  • 2019 - 2022 マラリア原虫が持つ四重包膜オルガネラ内へのタンパク質輸送メカニズムの解明
  • 2016 - 2020 感染性胃腸炎を引き起こす病原性細菌のヘム・鉄代謝機構の解明
  • 2018 - 2019 抗マラリア薬の標的としてのアピコプラスト還元力供給システムの立体構造解明
  • 2011 - 2015 フェレドキシンとそのパートナー蛋白質群との連結による電子伝達・分配への摂動
  • 2001 - 2004 プラスチドのレドックス代謝ネットワークを制御する分子基盤の研究
Show all
Papers (35)：
  • Yoko Kimata-Ariga, Rina Shinkoda, Ryuya Abe. Inter-domain interaction of ferredoxin-NADP+ reductase important for the negative cooperativity by ferredoxin and NADP(H). The Journal of Biochemistry. 2023. 174. 4. 327-334
  • Yoko Kimata-Ariga, Yoshiro Nishimizu, Rina Shinkoda. Molecular mechanism of negative cooperativity of ferredoxin-NADP + reductase by ferredoxin and NADP(H): role of the ion pair of ferredoxin Arg40 of and FNR Glu154. The Journal of Biochemistry. 2022. 172. 6. 377-383
  • Yoko Kimata-Ariga, Karen Fukuta, Masayuki Miyata. Role of Histidine 78 of leaf ferredoxin in the interaction with ferredoxin-NADP+ reductase: regulation of pH dependency and negative cooperativity with NADP(H). Bioscience, Biotechnology, and Biochemistry. 2022. 86. 5. 618-623
  • Y. Kimata-Ariga, R. Morihisa. Effect of artemisinin on the redox system of NADPH/FNR/ferredoxin from malaria parasites. Antioxidants. 2022. 11. 273
  • Yoko Kimata-Ariga, Rena Morihisa. Functional analyses of plasmodium ferredoxin Asp97Tyr mutant related to artemisinin resistance of human malaria parasites. The Journal of Biochemistry. 2021. 170. 4. 521-529
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MISC (21)：
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Patents (2)：
  • 薬剤スクリーニング方法、組換えベクター、形質転換体およびアピコンプレキサン類原虫により引き起こされる疾病に対する治療用組成物
  • 鉄硫黄タンパク質、タンパク質-FAD複合体、電子伝達剤、およびフェレドキシン活性阻害の測定方法
Books (6)：
  • NMR analysis of ferredoxin tethered to ferredoxin-NADP+ reductase in various configurations
    Prensas Universitarias de Zaragoza 2008 ISBN:9788477330172
  • Flavin and Flavoproteins 2008, NMR analysis of ferredoxin tethered to ferredoxin-NADP+ reductase in various configurations. In: Frago S, Gomez-Moreno C and Medina M, eds
    INO Reproducciones, S. A. 2008 ISBN:9788477330172
  • 植物の生化学・分子生物学, 原著「Biochemistry and Molecular Biology of Plants」
    学会出版センター 2005
  • 無敵のバイオテクニカルシリーズ 特別編「タンパク質実験の進めかた」
    羊土社 1998
  • Substitutions of artificial amino acids, O-methyl-Thr, O-methyl-Asp, S-methyl-Cys and 3-amino-Ala, for Thr-252 of cytochrome P450cam : probing the importance of the hydroxyl group of Thr-252 for oxygen activation. In : Ishimura Y, ed
    Oxygen Homeostasis and Its Dynamics. Springer-Verlag 1997
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Lectures and oral presentations  (18)：
  • Molecular mechanism by which NADP (H) allosterically suppresses the affinity between ferredoxin:NADP+reductase and ferredoxin
    (2022)
  • Functional analyses of Plasmodium ferredoxin mutant related to artemisinin resistance
    (2021)
  • Interactions between aromatic amino acid residues important for the binding of ferredoxin and ferredoxin-NADP(H) oxidoreductase from malaria parasite: possible involvement for artemisinin resistance
    (2020)
  • Maize leaf FNR mutations of NADP(H) binding site modulate the negative cooperativity between ferredoxin and NADP(H)
    (2018)
  • Ligand recognition in malaria parasite Tic 22 and search for the inhibitors.
    (2018)
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Education (3)：
  • 1990 - 1993 North Carolina state University Biochemistry Biochemistry
  • 1988 - 1990 Nagoya University
  • 1984 - 1988 Nagoya University School of Agricultural Sciences
Professional career (2)：
  • PhD. of Biochemistry
  • (BLANK)
Work history (4)：
  • 2023/10 - 現在 Department of Biological Chemistry, College of Agriculture, Graduate School of Sciences and Technology for Innovation, Yamaguchi University
  • 2016/04 - 2023/09 Department of Biological Chemistry, College of Agriculture, Graduate School of Sciences and Technology for Innovation, Yamaguchi University
  • 1997/02 - 2016/03 Osaka University Institute for Protein Research Assistant Professor
  • 1993/04 - 1997/01 Keio University, Research Assistant
Awards (1)：
  • 2017/01 - 国際ソロプチミスト枚方ー中央 クラブ賞 マラリア原虫が持つユニークな植物由来のエネルギー供給システムの研究
Association Membership(s) (1)：
日本生化学会
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