Mizuno Mamoru

ミズノマモル | Mizuno Mamoru

Affiliation and department：
Job title： Head
Homepage URL (1)： http://www.noguchi.or.jp/

Research field (5)： Biochemistry , Synthetic organic chemistry , Bioorganic chemistry , Structural/physical organic chemistry , Molecular biochemistry

Research keywords (8)： Glycoprotein , Glycopeptide , フルオラス化学 , 糖質科学 , 糖鎖合成 , Fluorous Chemistry , Oligosaccharide , Glycochemistry

Research theme for competitive and other funds (12)：

2021 - 2024 キレーター含有糖ユニットで修飾した抗体の標識反応と評価
2013 - 2016 Design, syntheses and diagnostic applications of beta(1-6)-linked glycolipids (GGLs) as the major cell membrane components of Mycoplasma pneumoniae
2012 - 2015 糖鎖シルセスキオキサン型プローブを用いる抗糖鎖抗体スクリーニングシステムの開発
2012 - 2014 ピロリ菌に直接効果のある物質の簡易調製
2007 - 2009 Development of functional glyco-devices using fluorous interaction

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Papers (82)：

Rieko Imae, Naoyuki Kuwabara, Hiroshi Manya, Tomohiro Tanaka, Masato Tsuyuguchi, Mamoru Mizuno, Tamao Endo, Ryuichi Kato. The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on α-dystroglycan. Genes to cells : devoted to molecular & cellular mechanisms. 2021. 26. 7. 485-494
Shou Takashima, Masaki Kurogochi, Wataru Tsukimura, Masako Mori, Kenji Osumi, Shu-Ichi Sugawara, Junko Amano, Mamoru Mizuno, Yoshio Takada, Akio Matsuda. Preparation and biological activities of anti-HER2 monoclonal antibodies with multi-branched complex-type N-glycans. Glycobiology. 2021
Shou Takashima, Masaki Kurogochi, Kenji Osumi, Shu-Ichi Sugawara, Mamoru Mizuno, Yoshio Takada, Junko Amano, Akio Matsuda. Novel endo-β-N-acetylglucosaminidases from Tannerella species hydrolyze multibranched complex-type N-glycans with different specificities. Glycobiology. 2020. 30. 11. 923-934
Masaki Kurogochi, Akio Matsuda, Mamoru Mizuno. Preparation of O-Glycopeptides from commercial bovine whey proteins using offline liquid chromatography-Mass spectrometry. Carbohydrate research. 2020. 491. 107981-107981
Kohtaro Goto, Masaki Kurogochi, Shou Takashima, Masako Mori, Akio Matsuda, Mamoru Mizuno. Site-specific protein PEGylation catalyzed by endo-β-N-acetylglucosaminidase. Tetrahedron Letters. 2020. 61. 6. 151475-151475

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MISC (89)：

水野真盛, 後藤浩太朗, 大隅賢二, 森昌子, 月村亘, 筒井正斗, 弘瀬友理子, 高田美生, 杉智和. 抗体中の糖鎖を薬物搭載部位とするADCの足場剤開発. 日本抗体学会学術大会プログラム・抄録集(Web). 2022. 1st
後藤浩太朗, 森昌子, 月村亘, 大隅賢二, 弘瀬友理子, 筒井正斗, 黒河内政樹, 石田秀樹, 松崎祐二, 高田美生, et al. One-pot synthesis of antibody-drug conjugate (ADC) precursor with Azido-PEGylated oxazoline. 日本薬学会年会要旨集(Web). 2022. 142nd
筒井正斗, 後藤浩太朗, 二木祐樹, 弘瀬友理子, 森昌子, 八須和子, 水野真盛. Synthesis of ADC precursor with functional group for SPIEDAC reaction. 日本糖質学会年会要旨集. 2022. 41st
筒井正斗, 後藤浩太朗, 大隅賢二, 浜元健太, 弘瀬友理子, 高島晶, 水野真盛. Synthesis of glycan derivatives for site-specific antibody-drug conjugates and evaluation of their transfer activity. 日本糖質学会年会要旨集. 2021. 40th
水野真盛, 後藤浩太朗, 森昌子, 月村亘, 大隅賢二, 弘瀬友理子, 筒井正斗, 黒河内政樹, 石田秀樹, 松崎祐二, et al. Synthesis of antibody-drug conjugate (ADC) precursor using PEGylated disaccharide oxazoline derivative. 日本糖質学会年会要旨集. 2021. 40th

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Books (3)：

複合糖質の化学と最新応用技術
シーエムシー出版 2009
フルオラスケミストリー
シーエムシー出版 2005
Handbook of Fluorous Chemistry
VCH-Wiley 2004

Education (5)：

1999 - Tokyo University of Science
- 1994 Tokyo University of Science Graduate School of Science
- 1994 Tokyo University of Science Graduate School, Division of Natural Science Chemistry
- 1992 Tokyo University of Science
- 1992 Tokyo University of Science Faculty of Science

Professional career (2)：

(BLANK) (Tokyo University of Science)
(BLANK)

Committee career (2)：

2009 - 2011 日本糖質学会評議員
日本糖質学会評議員

Awards (1)：

2003 - 日本ペプチド学会奨励賞

Association Membership(s) (4)：

日本糖質学会 , 日本ペプチド学会 , 日本化学会 , フルオラス科学研究会

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