Kubota Ryuji

クボタリュウジ | Kubota Ryuji

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.kufm.kagoshima-u.ac.jp/~bunshi/

Research field (2)： Neurology , Immunology

Research keywords (3)： human T-lymphotropic virus type 1 (HTLV-1) , HTLV-1-associated myelopathy (HAM) , cytotoxic T lymphocyte

Research theme for competitive and other funds (15)：

2022 - 2025 HTLV-1関連脊髄症(HAM)の自然免疫解析による病態解明と新規治療研究
2016 - 2023 HTLV-1関連眼疾患の診断法確立のための臨床的研究
2019 - 2021 HTLV-1感染細胞を標的としたHAMの新規治療法開発
2015 - 2018 Development of HTLV-1 peptide vaccine for treatment and prevention of ATL
2016 - 2018 中国福健省ならびに台湾と西南日本におけるHTLV-1関連疾患の比較研究

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Papers (88)：

Madoka Kuramitsu, Haruka Momose, Yuichiro Uchida, Kenji Ishitsuka, Ryuji Kubota, Masahito Tokunaga, Atae Utsunomiya, Kunihiko Umekita, Yuuki Hashikura, Kisato Nosaka, et al. Performance evaluation of Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test for different diagnostic situations. Microbiology spectrum. 2023. e0207823
EIJI MATSUURA, Nozuma S, Shigehisa A, Dozono M, Nakamura T, Tanaka M, Kubota R, Hashiguchi A, Takashima H. HTLV-1-associated myelopathy/tropical spastic paraplegia with sporadic late-onset nemaline myopathy: a case report. BMC musculoskeletal disorders. 2023
EIJI MATSUURA, Nozuma S, Dozono M, Daisuke Kodama, Masakazu Tanaka, Kubota R, Takashima H. Iliopsoas Muscle Weakness as a Key Diagnostic Marker in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). Pathogens (Basel, Switzerland). 2023
Nozuma S, Matsuura E, Masakazu Tanaka, Daisuke Kodama, Matsuzaki T, Yoshimura A, Sakiyama Y, Nakahata S, Morishita K, Yoshimi Enose-Akahata, et al. Identification and tracking of HTLV-1-infected T cell clones in virus-associated neurologic disease. JCI insight. 2023
Nagata R, Matsuura E, Nozuma S, Dozono M, Noguchi Y, Ando M, Hiramatsu Y, Kodama D, Tanaka M, Kubota R, et al. Anti-ganglionic acetylcholine receptor antibodies in functional neurological symptom disorder/conversion disorder. Frontiers in neurology. 2023

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MISC (66)：

兒玉大介, 田中正和, 松崎敏男, 松崎敏男, 野妻智嗣, 松浦英治, 高嶋博, 出雲周二, 久保田龍二. HAM診断に適した髄液中抗HTLV-1抗体検査法. 日本神経学会学術大会プログラム・抄録集. 2022. 63rd
兒玉大介, 田中正和, 松崎敏男, 松崎敏男, 野妻智嗣, 松浦英治, 高嶋博, 出雲周二, 久保田龍二. 抗HTLV-1抗体髄液検査はCLIA法が適している. Neuroinfection (Web). 2022. 27. 2
田中正和, 有島志保, 三輪正直, 野妻智嗣, 松浦英治, 高嶋博, 出雲周二, 久保田龍二. HAMにおけるPARP活性化を介した神経細胞死の検討. Neuroinfection (Web). 2022. 27. 2
児玉大介, 田中正和, 松崎敏男, 松崎敏男, 野妻智嗣, 松浦英治, 高嶋博, 出雲周二, 久保田龍二. 髄液中抗HTLV-1抗体検査とHAM診断. 日本HTLV-1学会学術集会. 2021. 7th
Satoshi Nozuma, Ryuji Kubota, Steven Jacobson. Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis. Journal of NeuroVirology. 2020. 26. 5. 652-663

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Books (9)：

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Education (1)：

Professional career (1)：

Work history (7)：

2019/04 - 現在 Joint Research Center for Human Retrovirus Infection, Kagoshima University Professor
2016/06 - 2019/03 Center for Chronic Viral Diseases, Kagoshima University Professor
2004/02 - 2016/05 Center for Chronic Viral Diseases, Kagoshima University Associate Professor
2004/01 - 2004/01 Faculty of Medicine, Kagoshima University Lecturer
2001/07 - 2003/12 Faculty of Medicine, Kagoshima University Assistant Professor

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Committee career (4)：

Association Membership(s) (5)：

日本HTLV-1学会 , 日本神経感染症学会 , 日本神経免疫学会 , 日本内科学会 , Societas Neurological Japonica

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