Rchr
J-GLOBAL ID:200901025964901130
Update date: Oct. 02, 2024
Takashi Sasaki
ササキ タカシ | Takashi Sasaki
Affiliation and department:
Job title:
Assistant Professor/Senior Assistant Professor
Research keywords (4):
Atopic dermatitis
, genomic sequence analysis
, Genome sequencing
, Longevity
Research theme for competitive and other funds (3):
- 2024 - 2027 Identification of pathways associated with cognitive resilience mechanisms using the Cent.PGS, healthspan genetic indicator.
- 2020 - 2023 超高齢者ゲノムコホートを用いたフレイル関連遺伝子探索と遺伝子リスク評価法の確立
- 2016 - 2019 黄色ブドウ球菌増殖を伴う皮膚炎自然発症モデルマウスを用いた皮膚炎発症機構解明
Papers (126):
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Akiharu Kubo, Takashi Sasaki, Hisato Suzuki, Aiko Shiohama, Satomi Aoki, Showbu Sato, Harumi Fujita, Noriko Ono, Noriko Umegaki-Arao, Tomoko Kawai, et al. Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes. The Journal of investigative dermatology. 2019. 139. 12. 2458-2466
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Saito S, Tanaka R, Sasaki T, Aoki S, Yasuhara R, Nakayama Y, Nagai T, Sonobe H, Ozawa Y, Kubo A. Subclinical hypopigmentation of the skin and hair in a Japanese patient with Hermansky-Pudlak syndrome type 3. The Journal of dermatology. 2019. 47. 1. e18-e20
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Sasaki T, Nishimoto Y, Abe Y, Takayama M, Hirose N, Okano H, Arai Y. Sex-specific effects of apolipoprotein ε4 allele on mortality in very old and centenarian Japanese men. The journals of gerontology. Series A, Biological sciences and medical sciences. 2019. 75. 10. 1874-1879
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Sasaki T, Nishimoto Y, Hirose N, Arai Y. [Genetic Protective Factors for Dementia Isolated by Centenarian Researches]. Brain and nerve = Shinkei kenkyu no shinpo. 2019. 71. 10. 1061-1070
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Uwamino, Y, Kubota, H, Sasaki, T, Kosaka, A, Furuhashi, M, Uno, S, Kudoh, J, Murata, M, Hasegawa, N. Recovery of FRI-5 carbapenemase at a Japanese hospital where FRI-4 carbapenemase was discovered. J Antimicrob Chemother. 2019. 74. 11. 3390-3392
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MISC (17):
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佐々木貴史, 西本祥仁, 広瀬信義, 新井康通. 認知症アンチリスク集団としての百寿者と抗認知症遺伝子研究. BRAIN and NERVE. 2019. 71. 10. 1061-1070
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Arai Y, Sasaki T, Hirose N. Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Honshu, Japan: Part 2 Honshu, Japan. Mech Ageing Dev. 2017. S0047-6374. 16
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佐々木貴史, 塩濱愛子, 天谷雅行. 皮膚バリア異常を示す自然発症皮膚炎モデルマウス. 日本臨床免疫学会会誌. 2014. 37. 3
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雅行, 佐々木 貴史. フィラグリン(fillagrin). 分子消化器病. 2014. 11(2). 2. 88-93
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佐々木貴史, 天谷雅行. アトピー生皮膚炎の皮膚バリアからみた病態. 臨床免疫・アレルギー科. 2013. 60. 3
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Lectures and oral presentations (179):
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アポリポタンパク質E ε4アレルは超高齢期男性において有意に生存に影響する
(第61回日本老年医学会学術集会 2019)
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百寿者に学ぶ認知症の防御因子
(日本認知症学会学術集会 2018)
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認知症臨床ゲノム情報データベース構築に関する開発研究
(日本認知症学会学術集会 2018)
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Whole genome sequencing-based association study for longevity with Japanese supercentenarians
(Living to 100 Symposium 2018)
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Whole genome sequencing-based association study for longevity with Japanese supercentenarians
(International Centenarian Consortium meeting 2018)
more...
Education (2):
- 1994 - 1996 Aoyama Gakuin University Graduate School of Science and Engineering Chemistry
- 1994 - 1996 Aoyama Gakuin University Graduate School of Science and Engineering Chemistry
Professional career (1):
Work history (6):
- 2015/01 - 現在 Keio University School of medicine. Center for Supercentenarian Research, Assistant Professor,
- 2011/02 - 2014/12 Keio University School of medicine. Dept. of Dermatology Project Assistant Professor
- 2010/01 - 2011/01 Tokyo University of Science. Project Assistant Professor
- 2001/04 - 2009/12 Keio University School of medicine Dept. Mol. Biol., Research Assistant
- 1998/05 - 2001/03 Keio University School of medicine Dept. Mol. Biol., Project Instructor
- 1996/04 - 1998/04 Taisho Pharmaceutical Co., Ltd. Researcher
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Committee career (2):
- 2012/12 - 現在 日本研究皮膚科学会 評議委員
- 2012/12 - 現在 日本研究皮膚科学会 評議委員
Awards (3):
- 2013/11 - 日本臨床免疫学会総会 優秀演題賞
- 2013/07 - 日本炎症再生医学会 優秀演題症
- 2007/07 - 日本遺伝子診療学会 日本遺伝子診療学会大会 奨励賞
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