Rchr
J-GLOBAL ID：200901026204800410   Update date: Aug. 22, 2024

Takaki Satoshi

タカキ サトシ | Takaki Satoshi
Affiliation and department：
National Center for Global Health and Medicine Research Institute, Department of Immune Regulation

About National Center for Global Health and Medicine Research Institute, Department of Immune Regulation


Job title： Director
Homepage URL  (2)： http://www.ri.ncgm.go.jp/department/hep/03/abstract.html ,  http://www.ri.ncgm.go.jp/department/hep/03/index_en.html
Research field  (1)： Immunology
Research keywords  (4)： 免疫学 ,  サイトカイン ,  リンパ球 ,  免疫疾患
Research theme for competitive and other funds  (42)：
  • 2022 - 2025 IL-5/好酸球/脂質代謝軸を介する新規炎症抑制機構の解明と制御
  • 2017 - 2021 Obesity-induced activation of cytokine-producing cells and eosinophils in adipose tissues.
  • 2017 - 2020 Roles of disease associated gene Lnk/Sh2b3 in inflammation.
  • 2015 - 2018 Activation machinery of tissue-resident innate IL-5-producing cells and their roles in inflammatory diseases and fibrosis
  • 2013 - 2016 Mechanisms of impaired granulopoiesis by streptococcus toxic shock
Show all
Papers (43)：
  • Masanori Iseki, Shinya Hidano, Fujimi Kudo, Satoshi Takaki. Control of germinal center B cell survival and IgE production by an adaptor molecule containing PH and SH2 domains, Aps/Sh2b2. Scientific reports. 2024. 14. 1. 17767-17767
  • Takashi Sekiya, Shinya Hidano, Satoshi Takaki. Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells. Cell Reports. 2024. 43. 3. 113954-113954
  • Kazunori Matsumura, Taizo Mori, Taeko Dohi, Yuki I Kawamura, Satoshi Takaki. Composition of fatty acids in a high-fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells. European journal of immunology. 2024. e2350800
  • Takashi Sekiya, Shizuko Kagawa, Katsunori Masaki, Koichi Fukunaga, Akihiko Yoshimura, Satoshi Takaki. Regulation of peripheral Th/Treg differentiation and suppression of airway inflammation by Nr4a transcription factors. iScience. 2021. 24. 3. 102166-102166
  • Hyuk Soon Kim, Min Bum Lee, Dajeong Lee, Keun Young Min, Jimo Koo, Hyun Woo Kim, Young Hwan Park, Su Jeong Kim, Masashi Ikutani, Satoshi Takaki, et al. The regulatory B cell-mediated peripheral tolerance maintained by mast cell IL-5 suppresses oxazolone-induced contact hypersensitivity. Science Advances. 2019. 5. 7
ｍore...
MISC (139)：
  • Satoshi Takaki. IL-5-producing ILC2s and eosinophils in the development of pulmonary arteriopathy. CYTOKINE. 2017. 100. 64-64
  • Jun Hee Lee, Seung Taek Ji, Jaeho Kim, Satoshi Takaki, Takayuki Asahara, Young-Joon Hong, Sang-Mo Kwon. Specific disruption of Lnk in murine endothelial progenitor cells promotes dermal wound healing via enhanced vasculogenesis, activation of myofibroblasts, and suppression of inflammatory cell recruitment (vol 7, 158, 2016). STEM CELL RESEARCH & THERAPY. 2017. 8
  • Makoto Otsu, Nao Suzuki, Satoshi Yamazaki, Tomoyuki Yamaguchi, Motohito Okabe, Hideki Masaki, Satoshi Takaki, Hiromitsu Nakauchi. A possible therapeutic strategy for genetic diseases using hematopoietic stem cells generated from induced pluripotent stem cells. HUMAN GENE THERAPY. 2013. 24. 12. A41-A42
  • Koji Eto, Hitoshi Takiza, Satoshi Takaki, Hidekazu Nishikii, Atsushi Oda, Hiromitsu Nakauchi. The cytokine signal inhibitor lnk promotes alpha IIb beta 3 integrin outside-in signaling through beta 3 tyrosine phosphorylation in platelets. BLOOD. 2007. 110. 11. 1067A-1067A
  • TAKIZAWA Hitoshi, TAKATSU Kiyoshi, TAKAKI Satoshi. Transient blocking of Lnk-mediated pathways as a potential approach to promote engrafting ability of hematopoietic progenitor cells. Inflammation and regeneration. 2007. 27. 1. 59-64
ｍore...
Books (6)：
  • 造血およびB細胞産生を制御する抑制性アダプター蛋白質Lnk.
    中外医学社「Annual Review 免疫2003」 2002
  • IL-5レセプターとシグナル伝達.
    Annual Review免疫1994 1994
  • Interleukin-5 receptor.
    Eosinophils in Allergy and Inflamation 1994
  • Interleukin-5 receptor.
    Eosinophils in Allergy and Inflamation 1994
  • Interleukin-5 and its receptor system in the immune system.
    Horizon in Cytokine Research, the Third International Mochida Memorial Symposium 1993
ｍore...
Professional career (1)：
  • M.D., Ph.D (Kumamoto University)
Work history (1)：
  • 2006 - 現在 National Center for Global Health and Medicine Department of Immune Regulation Director
Awards (1)：
  • 2002 - 日本炎症・再生医学会奨励賞
Association Membership(s) (10)：
日本炎症・再生学会 ,  日本分子生物学会 ,  American Association for the Advancement of Science ,  日本癌学会 ,  日本免疫学会 ,  The Japanese Society of Inflammation and Regeneration ,  The Molecular Biology Society of Japan ,  American Association for the Advancement of Science ,  The Japanese Cancer Association ,  The Japnese Society for Immunology
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