Rchr
J-GLOBAL ID：200901026886842918   Update date: Nov. 14, 2024

Yasui Hironobu

ヤスイ ヒロノブ | Yasui Hironobu
Affiliation and department：
Hokkaido University Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medcine

About Hokkaido University Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medcine


Job title： Associate Professor
Homepage URL  (2)： https://www.vetmed.hokudai.ac.jp/organization/radbiol/ ,  http://www.hokudai.ac.jp/radiois/kenkyu_top_eng.html
Research field  (4)： Environmental effects of chemicals ,  Environmental effects of radiation ,  Veterinary medicine ,  Radiology
Research keywords  (7)： Ferroptosis ,  Senescence ,  核医学 ,  イメージング ,  放射線生物学 ,  低酸素 ,  放射線腫瘍学
Research theme for competitive and other funds  (26)：
  • 2024 - 2027 Development of PET/EPR functional imaging method for early diagnosis of cancer
  • 2024 - 2027 Development of a New Dosimetry Technique Using Air Dose Rates for Nuclear Medicine Theranostics
  • 2022 - 2027 多価効果と代謝性リンカーの融合による革新的核医学治療薬の開発
  • 2023 - 2026 Research for local control and high accuracy of cancer senolytic therapy by non-invasive imaging
  • 2023 - 2026 内因性抗酸化物質を指標とした非侵襲な脳内酸化ストレス状態定量的評価手法の新規構築
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Papers (81)：
  • Kei Higashikawa, Riho Uehara, Sawako Horiguchi, Yuki Shibata, Naoto Okubo, Yuki Mizuno, Hironobu Yasui, Shunsuke Ohnishi, Hiroshi Takeda, Yuji Kuge. Thymidine Phosphorylase Imaging Probe for Differential Diagnosis of Metabolic dysfunction-associated Steatohepatitis. Molecular imaging and biology. 2024
  • Misa Oba, Mai Taguchi, Yohei Kudo, Koya Yamashita, Hironobu Yasui, Shingo Matsumoto, Igor A. Kirilyuk, Osamu Inanami, Hiroshi Hirata. Partial Acquisition of Spectral Projections Accelerates Four-dimensional Spectral-spatial EPR Imaging for Mouse Tumor Models: A Feasibility Study. Molecular Imaging and Biology. 2024
  • Koya Yamashita, Hironobu Yasui, Tomoki Bo, Masaki Fujimoto, Osamu Inanami. Mechanism of the Radioresistant Colorectal Cancer Cell Line SW480RR Established after Fractionated X Irradiation. Radiation research. 2024
  • Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C Emoto, Hirotada G Fujii, Maciej M Kmiec, Periannan Kuppusamy, Yuki Mizuno, Yuji Kuge, Masaki Nagane, et al. Feasibility study of multimodal imaging for redox status and glucose metabolism in tumor. Free radical biology & medicine. 2024
  • Tetsuro Tada, Yuki Mizuno, Yuki Shibata, Hironobu Yasui, Yuji Kuge. Application of copper (I) selective ligands for PET imaging of reactive oxygen species through metabolic trapping. Nuclear Medicine and Biology. 2024. 108914-108914
ｍore...
MISC (34)：
  • 安井博宣, 小澤拓実, 藤本政毅, 稲波修. 老化細胞標的がん治療 -がんセノセラピー-に向けた基礎研究. Precision Medicine. 2023. 6. 13. 1096-1100
  • 安井 博宣, 小澤 拓実, 藤本 政毅, 稲波 修. 細胞老化の制御に基づく新しいがん治療戦略. 細胞. 2023. 55. 2. 115-118
  • Possibility of a new radiotherapy combining glutamine metabolism inhibition and senolysis. Agricultural biotechnology. 2021. 5. 13. 1159-1164
  • Possibility of a new radiotherapy combining glutamine metabolism inhibition and senolysis. The CELL. 2021. 53. 12. 774-777
  • 稲波修, 安井博宣. Mechanism for radiosensitization of nanoparticle in cancer cells. Chemical Industry. 2021. 72. 4. 238-243
ｍore...
Patents (3)：
  • 放射線増感剤
  • ジクロロ酢酸を側鎖に担持する親水-疎水性共重合体及びそれらの医療用途
  • 陽子線治療用増感剤および陽子線治療方法
Books (6)：
  • 酸化ストレスの医学〈第三版〉
    診断と治療社 2024 ISBN:9784787826206
  • 放射線生物学〈第二版〉
    近代出版 2018 ISBN:9784874022467
  • 放射線生物学
    近代出版 2015 ISBN:9784874022139
  • 酸化ストレスの医学〈第二版〉
    診断と治療社 2014 ISBN:9784787821188
  • 小動物の実践歯科学 : 歯, 口腔, 上顎顔面部の治療
    緑書房 2013 ISBN:9784895310352
ｍore...
Lectures and oral presentations  (208)：
  • がん特異的代謝と放射線感受性
    (第14回放射線生物学セミナー 2024)
  • Redox imaging of tumors with a novel compact and portable EPRI device and its potential for multimodal imaging
    (The Annual Meeting of the Society for Free Radical Biology and Medicine 2023 & SFRRI 21st Biennial Meeting 2023)
  • マウス扁平上皮癌におけるジクロロ酢酸を放出する自己組織化ナノ粒子の放射線増感作用について
    (日本放射線影響学会第66回大会 2023)
  • 腫瘍内におけるDNA 量の不均一性が放射線分割照射後の放射線抵抗性がん細胞の出現につながる
    (日本放射線影響学会第66回大会 2023)
  • マウス扁平上皮がん細胞SCCVIIにおける、Pluronic L64 で修飾したC60 フラーレン(C60/L64)の放射線増感効果
    (日本放射線影響学会第66回大会 2023)
ｍore...
Education (3)：
  • 2004 - 2008 Hokkaido University
  • 1998 - 2004 Hokkaido University School of Veterinary Medicine Veterinary Medicine
  • 1997 - 1998 Osaka University School of Science Department of Physics
Professional career (1)：
  • Doctor of Philosophy (Hokkaido University)
Work history (7)：
  • 2018/07 - 現在 Hokkaido University Laboratory of Radiation Biology Department of Applied Veterinary Sciences Graduate School of Veterinary Medicine Associate Professor
  • 2016/04 - 2018/06 Hokkaido University Central Institute of Isotope Science Associate Professor
  • 2009/09 - 2016/03 Hokkaido University Laboratory of Radiation Biology Department of Environmental Veterinary Sciences Graduate School of Veterinary Medicine Assistant Professor
  • 2009/09 - 2016/03 Graduate School of Veterinary Medicine, Hokkaido University Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Assistant Professor
  • 2012/03 - 2012/08 National Cancer Institute / National Institutes of Health Visiting Fellow
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Committee career (15)：
  • 2024/05 - 現在 日本酸化ストレス学会 理事
  • 2024/04 - 現在 International Association for the Sensitization of Cancer Treatment director
  • 2024/02 - 現在 電子スピンサイエンス学会 電子スピンサイエンス編集委員長
  • 2023/09 - 現在 日本放射線腫瘍学会生物部会 幹事
  • 2023/08 - 現在 日本獣医学会 評議委員
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Awards (9)：
  • 2024/05 - 日本酸化ストレス学会 日本酸化ストレス学会学術賞
  • 2023/07 - International Association for the Sensitization of Cancer Treatment Association Award of International Association for the Sensitization of Cancer Treatment
  • 2021/06 - 日本放射線腫瘍学会生物部会 生物部会賞
  • 2017/10 - 日本放射線影響学会 日本放射線影響学会奨励賞
  • 2015/11 - 電子スピンサイエンス学会 電子スピンサイエンス学会奨励賞
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Association Membership(s) (9)：
日本分子イメージング学会 ,  THE JAPANESE CANCER ASSOCIATION ,  INTERNATIONAL ASSOCIATION FOR THE SENSITIZATION OF CANCER TREATMENT ,  THE SOCIETY OF ELECTRON SPIN SCIENCE AND TECHNOLOGY ,  SOCIETY FOR FREE RADICAL RESEARCH JAPAN ,  THE JAPAN RADIATION RESEARCH SOCIETY ,  THE JAPANESE SOCIETY OF VETERINARY SCIENCE ,  Japan Radioisotope Association ,  Japanese Society for Radiation Oncology
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