Rchr
J-GLOBAL ID:200901027386557032   Update date: Jun. 25, 2024

Matsui Toshitaka

マツイ トシタカ | Matsui Toshitaka
Affiliation and department:
Job title: 准教授
Homepage URL  (2): http://www2.tagen.tohoku.ac.jp/lab/mizukami/http://www2.tagen.tohoku.ac.jp/lab/mizukami/html/index.html
Research field  (4): Inorganic and coordination chemistry ,  Biochemistry ,  Molecular biochemistry ,  Functional biochemistry
Research keywords  (5): heme catabolism ,  enzyme ,  reaction mechanism ,  oxygen activation ,  protein
Research theme for competitive and other funds  (22):
  • 2022 - 2024 Functional regulation of MhuD-type heme degrading enzyme by siderophore
  • 2020 - 2023 特殊ビリンの生体内検出とタンパク質ラベル化への応用
  • 2020 - 2022 ケージド中間体を用いた2種のヘム分解酵素の機構解明
  • 2015 - 2018 Critical essence hidden in two catabolic enzymes for biological pigments
  • 2015 - 2017 歪みに感応するヘム分解機構とその精密制御
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Papers (79):
  • Takato Mashita, Toshiyuki Kowada, Hayashi Yamamoto, Satoshi Hamaguchi, Toshizo Sato, Toshitaka Matsui, Shin Mizukami. Quantitative control of subcellular protein localization with a photochromic dimerizer. Nature Chemical Biology. 2024
  • Takao Fujisawa, Satoshi Takenaka, Lila Maekawa, Toshiyuki Kowada, Toshitaka Matsui, Shin Mizukami, Isao Naguro, Hidenori Ichijo. Zinc controls histone acetyltransferase KAT7 activity to maintain cellular zinc homeostasis. 2023
  • Toshitaka Matsui. Regulatory mechanism of formaldehyde release in heme degradation catalyzed by Staphylococcus aureus IsdG. Journal of Biological Chemistry. 2023. 299. 5. 104648-104648
  • Himadri S. Sarkar, Takato Mashita, Toshiyuki Kowada, Satoshi Hamaguchi, Toshizo Sato, Kento Kasahara, Nobuyuki Matubayasi, Toshitaka Matsui, Shin Mizukami. Arylazopyrazole-Based Photoswitchable Inhibitors Selective for Escherichia coli Dihydrofolate Reductase. ACS Chemical Biology. 2023. 18. 2. 340-346
  • Takato Mashita, Toshiyuki Kowada, Hayashi Yamamoto, Satoshi Hamaguchi, Toshitaka Matsui, Shin Mizukami. Quantitative and Repetitive Control of Subcellular Protein-Protein Interaction Using a Photochromic Dimerizer. ChemRxiv. 2022
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MISC (23):
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Books (1):
  • ヘムタンパク質の科学: 生理機能の理解とその展開に向けて
    エヌ・ティー・エス 2022 ISBN:4860437780
Lectures and oral presentations  (120):
  • Mechanism of formaldehyde release in the heme degradation by IsdG from Staphylococcus aureus
    (The 10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
  • Quantitative Mapping of Subcellular Labile Zn2+ Concentrations Using Localizable Small-Molecule Fluorescent Probes
    (10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
  • Time-Lapse Ratiometric Imaging of Mitochondrial pH during Mitophagy Using a Localizable Fluorescent Probe
    (10th Asian Biological Inorganic Chemistry Conference (AsBIC10) 2022)
  • Development of photochromic ligands for quantitative and photo-reversible protein labeling
    (2022)
  • 酵素の Chemistry を解明して何が言えるだろうか?
    (「生命金属科学」令和4年度夏の合宿 2022)
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Education (3):
  • 1995 - 1998 The Graduate University for Advanced Studies Graduate School, Division of Mathematical and Physical Science 構造分子科学専攻
  • 1993 - 1995 京都大学大学院 工学研究科 分子工学専攻
  • 1989 - 1993 Kyoto University Faculty of Engineering 石油化学科
Professional career (2):
  • 博士(理学) (The Graduate University for Advanced Studies)
  • 修士(工学) (Kyoto University)
Work history (5):
  • 2013/11 - 2023/03 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Associate Professor
  • 2005/09 - 2013/10 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Lecturer
  • 2001/04 - 2005/08 Tohoku University Institute of Multidisciplinary Research for Advanced Materials Assistant Professor
  • 2000/04 - 2001/03 Tohoku University Assistant Professor
  • 1998/04 - 2000/03 JSPS (Institute for Molecular Science) Postdoctoral Fellow
Association Membership(s) (3):
The Biophysical Society of Japan ,  日本生化学会 ,  日本化学会
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