Rchr
J-GLOBAL ID：200901028518191110   Update date: Mar. 29, 2024

Hinou Hiroshi

ヒノウ ヒロシ | Hinou Hiroshi
Affiliation and department：
Hokkaido University Faculty of Advanced Life Science Division of Advanced Transdisciplinary Sciences

About Hokkaido University Faculty of Advanced Life Science Division of Advanced Transdisciplinary Sciences


Job title： Professor
Homepage URL  (1)： https://sites.google.com/eis.hokudai.ac.jp/hinou/home
Research field  (11)： Chemical biology ,  Bioorganic chemistry ,  Synthetic organic chemistry ,  Analytical chemistry ,  Pharmaceuticals - chemistry and drug development ,  Bacteriology ,  Biochemistry ,  Applied biofunctional and bioprocess engineering ,  Nanobioscience ,  Green/sustainable/environmental chemistry ,  Environmental effects of chemicals
Research keywords  (9)： organic chemistry ,  生物有機化学 ,  糖鎖工学 ,  mass spectrometry ,  Analytical Chemistry ,  Surface chemistry ,  創薬化学 ,  environmentally-controlled chemistry ,  cyclic compounds
Research theme for competitive and other funds  (17)：
  • 2022 - 2026 Development of MALDI glycotyping technology targeting a wide range of biological samples.
  • 2021 - 2024 黄体の機能制御に重要な糖鎖の探索~alpha2,6シアル酸修飾に注目して
  • 2019 - 2023 Antibodies targeting dynamic epitopes generated by posttranslational protein glycosylation
  • 2019 - 2022 Analysis of immunological properties of mannose-based molecules and its action mechanisms.
  • 2021 - 2022 Correlation analysis of antigen glycosylation with immune response to infectious diseases
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Papers (107)：
  • Dereje G. Feleke, Bryan M. Montalban, Solomon T. Gizaw, Hiroshi Hinou. Sulfated N-glycans Upregulation in Sera Predicts Early-Stage Breast Cancer in Patients. 2024
  • Bryan M. Montalban, Hiroshi Hinou. Glycoblotting-Based Ovo-Sulphoglycomics Reveals Phosphorylated N-Glycans as a Possible Host Factor of AIV Prevalence in Waterfowls. ACS Infectious Diseases. 2024
  • Shogo Urakami, Hiroshi Hinou. Sodium-Doped 3-Amino-4-hydroxybenzoic Acid: Rediscovered Matrix for Direct MALDI Glycotyping of O-Linked Glycopeptides and Intact Mucins. International Journal of Molecular Sciences. 2023
  • Hiroshi Hinou. DHB Matrix with Additives for Direct MALDI Mass Spectrometry of Carbohydrates and Glycoconjugates. Trends in Glycoscience and Glycotechnology. 2023. 35. 204. E19-E22
  • Lareno L. Villones, Anna-Kristin Ludwig, Seiya Kikuchi, Rika Ochi, Shin-Ichiro Nishimura, Hans-Joachim Gabius, Herbert Kaltner, Hiroshi Hinou. Altering the Modular Architecture of Galectins Affects its Binding with Synthetic α-Dystroglycan O-Mannosylated Core M1 Glycoconjugates In situ. ChemBioChem. 2023
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MISC (124)：
  • 浦上彰吾, 比能洋. MALDI MSによる簡便・迅速な糖タンパク質糖鎖解析. 化学系学協会北海道支部冬季研究発表会(Web). 2022. 2022
  • 浦上彰吾, 比能洋. Development of O antigen rapid typing by MALDI-TOF MS. 質量分析総合討論会講演要旨集. 2022. 70th
  • 比能洋. シアリル化糖鎖・複合糖質の直接MALDI-TOFMS解析法. 日本糖質学会年会要旨集. 2019. 38th
  • 高山理沙, GEBREHIWOT Abrha Gebreselema, 加藤芳規, MARTIN Fayna Maria Garcia, 比能洋, 西村紳一郎. がん細胞の動的糖鎖修飾の解析によるバイオマーカーの探索. 日本化学会春季年会講演予稿集(CD-ROM). 2017. 97th
  • 比能洋, 比能洋. Glycoblotting型糖ペプチドマイクロアレイを用いた構造活性相関研究. 日本糖質学会年会要旨集. 2017. 36th
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Patents (16)：
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Books (1)：
  • 天然2糖を出発物とした有用化合物の合成研究
    比能洋 2000
Lectures and oral presentations  (127)：
  • Glycotyping: Old and New Concept of Glycoscience
    (108th Indian Science Congress 2023)
  • MALDI Glycotyping of Glycoproteins, Biofluids, and Bacterial O-antigens
    (International Congress on Pure and Applied Chemistry (ICPAC) Kota Kinabalu 2022 2022)
  • 糖鎖選択的イオン化技術(質量分析)、糖鎖機能探索技術(マイクロアレイ)
    (イノベーション・ジャパン2021 2021)
  • MALDI-TOFMSによる糖質解析 ~前処理工程をどれだけ簡素化できるか~
    (質量分析学会第29回北海道談話会 2021)
  • 化学者から見た糖鎖研究
    (異分野meetup week2020☆研究者コミュニティサロン☆“糖鎖研究について語ろう! 2020)
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Education (3)：
  • 1997 - 2000 Saitama University Graduate School of Science and Engineering Division of Biological and Environmental Sciences
  • 1995 - 1997 Saitama University Graduate School of Science and Engineering Division of Applied Chemistry
  • - 1995 Saitama University Faculty of Engineering
Professional career (1)：
  • PhD
Work history (14)：
  • 2019/04 - 現在 北海道大学 先端生命科学研究院 次世代物質生命科学研究センター副センタ-長
  • 2019/01 - 現在 Hokkaido University Faculty of Advanced Life Science Professor
  • 2013/04 - 2018/12 Hokkaido University Faculty of Advanced Life Science Associate Professor
  • 2007/10 - 2013/03 Hokkaido University Faculty of Advanced Life Science Assistant Professor
  • 2010/02 - 2010/09 Institute for Research in Biomedicine (IRB barcelona) Visiting researcher
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Committee career (14)：
  • 2021/04 - 現在 日本質量分析学会 日本質量分析学会北海道談話会・研究会 世話人
  • 2021/04 - 現在 高分子学会 代議員
  • 2020/04 - 現在 日本化学会 北海道支部幹事
  • 2019/07 - 現在 日本糖質学会 評議員
  • 2014 - 2023 GFRG GFRGシンポジウム運営委員
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Awards (6)：
  • 2023/03 - John Wiley & Sons, Inc. Top Downloaded Article Top Downloaded Article
  • 2022/03 - Analysis & Sensing. Most accessed 03/2022
  • 2011 - Best Poster Award
  • 2011 - Very Important Paper (VIP)
  • 2007 - 高分子研究奨励賞
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Association Membership(s) (6)：
The Mass Spectrometry Society of Japan ,  THE SOCIETY OF POLYMER SCIENCE, JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH ,  THE CHEMICAL SOCIETY OF JAPAN ,  GFRG Project
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