- 2017 - 2020 Molecular mechanism of skin cancer development by functional ambiguity of aPKC lamda
- 2014 - 2017 Role of INPP4B in melanoma development: possible effects of 3-BP as promising anticancer drug
- 2014 - 2016 Pathogenetic machanism for pyoderma gangrenosusm by disruption of the production pathway of phosphatidylinositol (3,5) biphosphate
- 2011 - 2013 Molecular basis of melanomagenesis based on the failure of pluripotency maintenance of melanocyte stem cells
- 2008 - 2010 Establishment of remodeling technologies for protein misfolding in keratin disorders using an inducible transgenic mouse model
- 2006 - 2007 Development of molecular target-based therapy of cutaneous squamous cell carcinoma by selective block of PI3K isoforms
- 2004 - 2005 Roles for stat3 in carcinogenesis mouse model of Cowden disease
- 2002 - 2003 Study of pathophysiology of keratin disease
- 2000 - 2001 Construction of keratin disease keratinocyte model
- 1999 - 2001 Development of the artificial organs from human stem cells.
- 1997 - 1998 Biological roles of peptidylarginine deiminase in the pathogenic mechanisms of keratin deseases : molecular biological approach
- 1995 - 1996 Effects of Mutant Keratin Genes in Transfected Epidermal Cells : Establishment of Cell Models for Genodermatoses
- 1993 - 1994 Suppression of gene expression of steroid sulfatase by antisense RNA : Establishment of cellular model for X-linked ichthyosis
- 1985 - 1986 先天性表皮水疱症の発症機序特に水疱惹起因子の同定とその活性制御機構について
- 1978 - 毛包バルジ領域幹細胞システムの運命決定機構
- 1978 - メラノーマおよび扁平上皮癌の分子病態
- carcinogenesis and stem cell biology
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