Hirano Seishiro

ヒラノセイシロウ | Hirano Seishiro

Affiliation and department：
Job title： Guest scientist
Homepage URL (1)： http://www.nies.go.jp/risk/members/hirano/nano/Index.html

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (5)： macrophage , nano , Arsenic , 毒性学 , Toxicology

Research theme for competitive and other funds (15)：

2018 - 2022 A basic study for health effects of cationic surfactants
2016 - 2017 A mechanistic approach of arsenic toxicity using SUMOylation of Promyelocytic Leukemia protein as an indicator.
2012 - 2015 Effects of exposure to nanomaterials or nanoparticles on human health
2014 - 2015 ナノファイバーのインフラマゾーム形成機構と毒性評価に関する研究
2011 - 2013 ヒ素結合タンパク質のキャラクタリゼーションと生態影響評価への応用

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Papers (105)：

Sanae Kanno, Seishiro Hirano, Jun Monma-Otaki, Hideaki Kato, Mamiko Fukuta, Yoshimi Nakamura, Yasuhiro Aoki. Plasma membrane damage triggered by benzalkonium chloride and cetylpyridinium chloride induces G0/G1 cell cycle arrest via Cdc6 reduction in human lung epithelial cells. The Journal of toxicological sciences. 2023. 48. 2. 75-86
Chaw Kyi-Tha-Thu, Yuji Fujitani, Seishiro Hirano, Tin-Tin Win-Shwe. Early-Life Exposure to Traffic-Related Air Pollutants Induced Anxiety-like Behaviors in Rats via Neurotransmitters and Neurotrophic Factors. International Journal of Molecular Sciences. 2022. 24. 1. 586-586
Tin-Tin Win-Shwe, Chaw Kyi-Tha-Thu, Yuji Fujitani, Shinji Tsukahara, Seishiro Hirano. Perinatal Exposure to Diesel Exhaust-Origin Secondary Organic Aerosol Induces Autism-Like Behavior in Rats. International journal of molecular sciences. 2021. 22. 2
Sanae Kanno, Seishiro Hirano, Tsubasa Sakamoto, Akiko Furuyama, Hiroshi Takase, Hideaki Kato, Mamiko Fukuta, Yasuhiro Aoki. Scavenger receptor MARCO contributes to cellular internalization of exosomes by dynamin-dependent endocytosis and macropinocytosis. Scientific Reports. 2020. 10. 1
Seishiro Hirano, Sanae Kanno. Relevance of autophagy markers to cytotoxicity of zinc compounds in macrophages. Toxicology in vitro : an international journal published in association with BIBRA. 2020. 65. 104816-104816

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MISC (66)：

Seishiro Hirano. Biotransformation of arsenic and toxicological implication of arsenic metabolites. Archives of Toxicology. 2020. 94. 8. 2587-2601
WIN-SHWE Tin-Tin, FUJITANI Yuji, HIRANO Seishiro. Neurotoxicity Assessment of Secondary Organic Aerosols by Intranasal and Inhalation Exposure in Mice (特集エアロゾルの毒性評価 : 曝露手法を中心に). エアロゾル研究. 2017. 32. 3. 169-175
T-T Win-Shwe, C. Kyi-Tha-Thu, Y. Moe, Y. Fujitani, S. Tsukahara, H. Nitta, S. Hirano. Establishment of an olfactory-based spatial learning test for preweaning mice and the effects of early exposure to diesel exhaust origin secondary organic aerosol. TOXICOLOGY LETTERS. 2015. 238. 2. S261-S261
ウィンシュイ・ティンティン, 藤谷雄二, 前川文彦, 柳澤利枝, 古山昭子, 野原恵子, 新田裕史, 平野靖史郎. ディーゼル排気由来SOAの胎児期幼児期曝露がマウスの社会行動・空間学習行動に及ぼす影響. 大気環境学会年会講演要旨集. 2014. 55回. 497-497
藤谷雄二, 佐藤圭, 古山昭子, 伏見暁洋, 伊藤智彦, 田邊潔, 平野靖史郎, 今村隆史, 高見昭憲. 二次生成有機エアロゾルの小規模チャンバーによる粒子発生法と毒性評価. エアロゾル科学・技術研究討論会. 2013. 30th. 29-30

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Education (4)：

- 1981 Waseda University
- 1981 Waseda University
- 1979 Waseda University
- 1979 Waseda University

Professional career (1)：

Doctor of Medical Science

Work history (1)：

1990/02 - 現在医学博士(東京大学)

Committee career (2)：

2011/08 - 現在 European Society of Toxicology Archies of Toxicology, Advisory Editor
2008/10 - 現在 Society of Toxocilogy Toxicol. Appl. Pharmacol. Associate Editor

Awards (3)：

日本衛生学会奨励賞 (1995年)
for Hygiene(1995)
Young Researcher Achievement Award from The Japanese Society

Association Membership(s) (5)：

Japanese Arsenic Scientist's Society , 免疫毒性研究会 , Japanese society for Immunology , Japanese society for Hygiene , Japanese society of Immunotoxicology

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