Rchr
J-GLOBAL ID:200901028973072900
Update date: Dec. 05, 2024
Masuda Mari
マスダ マリ | Masuda Mari
Affiliation and department:
Research field (1):
Medical biochemistry
Research keywords (5):
Reverse-phase Protein Array (RPPA)
, 分子標的治療薬
, バイオマーカー
, トランスレーショナルリサーチ
, プロテオミクス
Research theme for competitive and other funds (14):
- 2023 - 2025 線維化腫瘍に対する複合がん免疫療法の効果予測バイオマーカー確立
- 2023 - 2024 Establishment of a Reverse Phase Protein Array Platform for Diagnosis of Cancer High-Risk Groups Based on Genomic Instability.
- 2020 - 2023 Development of a diagnostic platform for precision oncology by applying reverse-phase phosphoprotein array to an analysis of formalin-fixed paraffin-embedded (FFPE) tissue
- 2022 - 2023 Establishment of a Reverse Phase Protein Array Platform for Diagnosis of Cancer High-Risk Groups Based on Genomic Instability.
- 2020 - 骨肉腫患者に新たな治療選択肢を;TNIK阻害剤による骨肉腫分化転換誘導を介した新規治療薬の開発
- 2017 - 2020 Identification of regulatory components of Wnt signaling in beta-catenin and T-cell factor-4 transcriptional complex as therapeutic targets for colorectal cancer
- 2019 - 2020 骨肉腫患者に新たな治療選択肢を; TNIK阻害剤による骨肉腫分化転換誘導を介した新規治療薬の開発
- 2019 - 2020 大腸がん幹細胞を標的とするTNIK阻害剤が作用する分子ネットワークの解明
- 2016 - 2019 Development of reverse-phase protein array platform for analyzing tissue samples and identification of biomarkers to guide the use of a TNIK inhibitor
- 2017 - 2018 大腸がん幹細胞を標的とするTNIK阻害剤が作用する分子ネットワークの解明
- 2018 - Development of a Novel Colorectal Cancer Therapeutic Targeting Gene Transcription in Cancer Stem Cells
- 2016 - 大腸がん幹細胞を標的とするTNIK阻害剤が作用する分子ネットワークの解明
- 2005 - 2009 Molecular understanding and diagnosis of human cancer through the structural, functional and expression analysis of cancer related genes.
- 2009 - 難治がんの創薬バイオマーカー探索研究
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Papers (54):
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Ayaka Tsuge, Sho Watanabe, Akihito Kawazoe, Yosuke Togashi, Kota Itahashi, Mari Masuda, Atsuo Sai, Shogo Takei, Hiromi Muraoka, Shuichi Ohkubo, et al. The HSP90 Inhibitor Pimitespib Targets Regulatory T Cells in the Tumor Microenvironment. Cancer immunology research. 2024
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Syuzo Kaneko, Ken Takasawa, Ken Asada, Kouya Shiraishi, Noriko Ikawa, Hidenori Machino, Norio Shinkai, Maiko Matsuda, Mari Masuda, Shungo Adachi, et al. Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations. Molecular cancer. 2024. 23. 1. 126-126
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Yoshiaki Maru, Mami Kohno, Kiyomi Suzuka, Akiko Odaka, Mari Masuda, Akinobu Araki, Makiko Itami, Naotake Tanaka, Yoshitaka Hippo. Establishment and characterization of multiple patient-derived organoids from a case of advanced endometrial cancer. Human cell. 2024
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Mari Masuda, Riko Nakagawa, Tadashi Kondo. Harnessing the potential of reverse-phase protein array technology: Advancing precision oncology strategies. Cancer science. 2024
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Takahiko Akiyama, Tadahito Yasuda, Tomoyuki Uchihara, Noriko Yasuda-Yoshihara, Benjy J Y Tan, Atsuko Yonemura, Takashi Semba, Juntaro Yamasaki, Yoshihiro Komohara, Koji Ohnishi, et al. Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors. Cancer research. 2023. 83. 5. 753-770
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MISC (89):
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増田万里. Role and Utility of Reverse Phase Protein Array Platform in Fundamental Innovative Oncology Core, National Cancer Center Institute. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)
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Shuichi Mitsunaga, Mari Masuda, Hiroki Yoshimatsu, Yoichi Kamei, Mitsuhito Sasaki, Kazuo Watanabe, Masafumi Ikeda. Abstract 2238: RAS activity-related features of metastatic pancreatic cancer. Cancer Reserach Volume 83, Issue 7_Supplement. 2023. 83. 7_Supplement
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Takeda S, Shiokawa D, Aoyama T, Yoshioka K, Okamoto K, Masuda M. Reverse-Phase Protein Array for Proteo-Epigenomic Profiling of Colorectal Cancer Patient-Derived Organoids. 日本癌学会学術総会抄録集(Web). 2023. 82nd
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鈴木 秀隆, 光永 修一, 増田 万里, 池田 公史, 吉松 宏樹, 亀井 陽一. 血清Growth differentiation factor 15濃度高値の進行膵がん患者の特徴(The characteristics of patients with high serum levels of growth differentiation factor 15 in advanced pancreatic cancer). 日本癌学会総会記事. 2022. 81回. P-3221
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Mari Masuda, Riko Nakagawa, Tadashi Kondo. Applicability of reverse phase protein array technology for further advancement of precision oncology. JPrOS2022(20th JHUPO). 2022. 20th
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Patents (4):
Professional career (2):
- 医学博士 (東京大学大学院医学系研究科)
- Master of Science (The Graduate School of Hood College)
Committee career (4):
- 2022/04 - 現在 日本患者由来がんモデル学会 理事及び監事
- 2020 - 現在 Japan Society of Clinical Proteogenomics Board member
- 2018/01 - 現在 Japanese Cancer Association Board member
- 2017/04 - 現在 international cancer proteogenome consortium (ICPC) ICPC Member
Association Membership(s) (4):
日本患者由来がんモデル学会
, 日本臨床プロテオゲノミクス学会
, Global Reverse-Phase Protein Array Society
, Japan Cancer Association
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