Rchr
J-GLOBAL ID:200901029013404158
Update date: Sep. 18, 2024
Takayuki Ikezoe
イケゾエ タカユキ | Takayuki Ikezoe
Affiliation and department:
Job title:
主任教授
Research field (1):
Hematology and oncology
Research keywords (3):
トロンボモジュリン
, 血管内皮細胞
, hematological malignancy
Research theme for competitive and other funds (20):
- 2024 - 2027 アスタチンー211標識ヒト・キメラCD82抗体による難治白血病に対する治療法の開発
- 2024 - 2027 トロンボモジュリン欠損患者 iPS細胞から成熟分化細胞の確立と機能解析及び患者還元
- 2023 - 2026 薬物送達システムとα線放出核種を組み合わせた革新的な白血病治療法の開発
- 2022 - 2025 Gas6/Merシグナルを標的とした新型コロナウイルスによる血栓症対策
- 2022 - 2025 造血細胞移植後VOD/SOSに対する新たな治療戦略
- 2021 - 2024 造血細胞移植における生着不全に対する新規治療戦略とバイオマーカーの探索
- 2020 - 2023 急性放射線障害に対するトロンボモジュリン分子の臨床応用
- 2020 - 2023 がん幹細胞をターゲットとしたα線放出核種を用いた革新的な白血病治療法の開発
- 2019 - 2022 骨髄異形成症候群における無効造血環境形成の血球動態に基づく基礎的検討
- 2019 - 2022 Thrombomodulin suppresses bleomycin-induced pulmonary fibrosis and develop to a new candidate for IPF treatment
- 2018 - 2021 Development of a novel treatment strategy to protect vascular endothelial cells with TM mutant
- 2018 - 2021 Intranuclear protein as a marker for early diagnosis of TA-TMA/SOS
- 2018 - 2021 A critical role of Gas6-TAM signaling pathway in the pathology of HSCT-associated TMA
- 2017 - 2020 Critical roles of Gas6 in the pathology of GVHD
- 2014 - 2017 A novel cytoprotective agent with thrombomodulin mutant
- 2012 - 2014 Mechanisms for systemic inflammation in COPD
- 2011 - 2014 Clinical application and expression mechanisms for KL-6/MUC1 having a selectin ligand
- 2011 - 2013 Development of novel treatment strategy with TM to protect vascular endothelium
- 2008 - 2010 Development of new treatment strategy targeting mitotic kinases in hematological malignancies
- 2005 - 2006 Aktシグナルのブロックによる造血器悪性腫瘍の制御の試み
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Papers (125):
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Naoshi Obara, Kensuke Usuki, Takeshi Hayashi, Masato Fujii, Takayuki Ikezoe. Burden of illness in Japanese patients with paroxysmal nocturnal hemoglobinuria receiving C5 inhibitors. International journal of hematology. 2024. 119. 3. 255-264
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Kiyohito Hayashi, Daisuke Koyama, Yuki Sato, Masahiko Fukatsu, Takayuki Ikezoe. Lymphoplasmacytic lymphoma presenting cold agglutinin syndrome: Clonal expansion of KMT2D and IGHV4-34 mutations after COVID-19. British journal of haematology. 2023
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Takahiro Sano, Koki Ueda, Keiji Minakawa, Tsutomu Mori, Yuko Hashimoto, Haruhiko Koseki, Yasuchika Takeishi, Kazuhiko Ikeda, Takayuki Ikezoe. Impaired Repopulating Ability of Uhrf2-/- Hematopoietic Progenitor Cells in Mice. Genes. 2023
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Yasuhiro Uchida, Daisuke Koyama, Kazuya Manabe, Kengo Suzuki, Naomi Asano, Mamiko Endo, Masahiko Fukatsu, Takahiro Sano, Kiyohito Hayashi, Motoki Takano, et al. High Efficacy and Safety of Asciminib in a Chronic Myeloid Leukemia Patient with Chronic Kidney Disease Following Renal Transplantation: A Case Report. Internal medicine (Tokyo, Japan). 2023
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Masahiko Fukatsu, Yoichi Hamazaki, Yuki Sato, Daisuke Koyama, Takayuki Ikezoe. A case of cold agglutinin syndrome associated with chronic lymphocytic leukaemia harbouring mutations in CARD11 and KMT2D. International journal of hematology. 2023
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MISC (159):
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Hirotaka Mori, Hiroshi Ohkawara, Ryuichi Togawa, Mami Rikimaru, Yoko Shibata, Takayuki Ikezoe. Diagnosis and treatment of disseminated intravascular coagulation in COVID-19 patients: a scoping review. International Journal of Hematology. 2021. 113. 3. 320-329
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Takayuki Ikezoe. Advances in the diagnosis and treatment of disseminated intravascular coagulation in haematological malignancies. International Journal of Hematology. 2021. 113. 1. 34-44
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趙松吉, 粟生木美穂, 趙景敏, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 高橋和弘, 伊藤浩, 伊藤浩, et al. 急性骨髄性白血病における211At標識抗CD82抗体の治療効果. 核医学(Web). 2021. 58. Supplement
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趙松吉, 粟生木美穂, 下山彩希, 趙景敏, 右近直之, 西嶋剣一, 鷲山幸信, 高橋和弘, 伊藤浩, 伊藤浩, et al. ヒト急性骨髄性白血病モデルマウスにおける211At標識抗CD82抗体の体内動態. 核医学(Web). 2021. 58. Supplement
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下山彩希, 粟生木美穂, 趙景敏, 右近直之, 西嶋剣一, 鷲山幸信, 高橋和弘, 伊藤浩, 織内昇, 池添隆之, et al. ヒト急性骨髄性白血病モデルマウスにおける211At標識抗CD33抗体の体内動態. 核医学(Web). 2021. 58. Supplement
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Work history (2):
- 2016/05 - 現在 Fukushima Medical University
- - 2016/04 Kochi University Research and Education Faculty, Medical Sciences Cluster Clinical Medicine Unit Lecturer
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