Rchr
J-GLOBAL ID：200901029414663741   Update date: Jul. 07, 2024

Suzuki Norio

スズキ ノリオ | Suzuki Norio
Affiliation and department：
Tohoku University New Industry Creation Hatchery Center

About Tohoku University New Industry Creation Hatchery Center


Job title： Professor
Other affiliations (1)：
Homepage URL  (1)： http://db.tohoku.ac.jp/whois/detail/bb0a50224e3c749f4738115554c68007.html
Research field  (3)： Medical biochemistry ,  Developmental biology ,  Molecular biology
Research keywords  (5)： 遺伝子改変マウス ,  erythropoietin ,  Hypoxia response ,  転写制御 ,  Transcriptional regulation
Research theme for competitive and other funds  (14)：
  • 2023 - 2026 Elucidation of renoprotective effects by pharmacological intervention into oxygen metabolism, using living renal cells from urine of diabetic kidney disease patients
  • 2021 - 2025 Diversity of fibroblasts brings versatility of organ interstitia
  • 2017 - 2019 腎臓の赤血球増殖因子産生細胞における血圧調節系と造血制御系のクロストーク(鈴木教郎)
  • 2015 - 2019 赤血球増殖因子の造血外機能の解明
  • 2014 - 2019 低酸素ストレスに対するシステミックな生体応答機構の解明
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Papers (112)：
  • Taku Nakai, Daisuke Saigusa, Koichiro Kato, Tomoko Fukuuchi, Seizo Koshiba, Masayuki Yamamoto, Norio Suzuki. The drug-specific properties of hypoxia-inducible factor-prolyl hydroxylase inhibitors in mice reveal a significant contribution of the kidney compared to the liver to erythropoietin induction. Life Sciences. 2024. 346. 122641-122641
  • Hiroki Sekine, Haruna Takeda, Norihiko Takeda, Akihiro Kishino, Hayato Anzawa, Takayuki Isagawa, Nao Ohta, Shohei Murakami, Hideya Iwaki, Nobufumi Kato, et al. PNPO-PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity. Nature Metabolism. 2024
  • Norio Suzuki, Yuma Iwamura, Koichiro Kato, Hirotaka Ishioka, Yusuke Konta, Koji Sato, Nao Uchida, Noa Koida, Hiroki Sekine, Tetsuhiro Tanaka, et al. Crosstalk between oxygen signaling and iron metabolism in renal interstitial fibroblasts. Journal of clinical biochemistry and nutrition. 2024. 74. 3. 179-184
  • Shimizu R, Hirano I, Hasegawa A, Suzuki M, Otsuki A, Taguchi K, Katsuoka F, Uruno A, Suzuki N, Yumoto A, et al. Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice. Commun Biol. 2023. 6
  • Taku Nakai, Yuma Iwamura, Koichiro Kato, Ikuo Hirano, Yotaro Matsumoto, Yoshihisa Tomioka, Masayuki Yamamoto, Norio Suzuki. Drugs activating hypoxia-inducible factors correct erythropoiesis and hepcidin levels via renal EPO induction in mice. Blood advances. 2023
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MISC (123)：
  • 中井琢, 鈴木教郎. Genetically modified mouse lines for investigating molecular pathology of renal anemia. 腎と透析. 2021. 91. 5
  • 宮崎 真理子, 宮内 健一郎, 佐藤 浩司, 鈴木 教郎. 【腎性貧血治療のこれまでと,その新しい展開】腎性貧血の発症機序. 臨床透析. 2021. 37. 1. 13-18
  • 佐藤 浩司, 鈴木 教郎. 【腎臓の構成細胞から再考する:基礎と臨床】間質の間質細胞・血管構成細胞 腎間質構成細胞の特徴と機能. 腎と透析. 2020. 89. 3. 402-407
  • 鈴木 教郎. 腎疾患を生化学的に解明する 腎臓エリスロポエチン産生細胞による個体レベルの低酸素応答機構. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [1S03m-04]
  • 中井 琢, 加藤 幸一郎, 鈴木 教郎. 低酸素誘導転写因子HIFを活性化する薬剤が病態腎の赤血球造血因子産生を再活性化する機序の検討. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [3Z10-609)]
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Education (4)：
  • - 2003 University of Tsukuba
  • - 2003 University of Tsukuba Graduate School, Division of Medicine
  • - 1997 University of Tsukuba
  • - 1997 University of Tsukuba Second Cluster of College
Professional career (1)：
  • Ph.D (University of Tsukuba)
Work history (8)：
  • 2022/01 - 現在 New Industry Creation Hatchery Center, Tohoku University Applied Oxygen Physiology Project Professor
  • 2016/04 - 2021/12 Tohoku University Graduate School of Medicine Associate Professor
  • 2012/02 - 2016/03 Tohoku University Graduate School of Medicine
  • 2011/01 - 2012/01 Tohoku University Graduate School of Medicine Lecturer
  • 2010/02 - 2011/01 Karolinska Institute Senior Research Manager
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Committee career (1)：
  • 2005/04 - 2007/03 独立行政法人 科学技術振興機構 遺伝子組換え実験安全委員
Association Membership(s) (2)：
日本生化学会 ,  日本分子生物学会
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