YABE Chihiro

ヤベチヒロ | YABE Chihiro

Affiliation and department：

Research field (2)： Metabolism and endocrinology , Pharmacology

Research keywords (3)：病態分子薬理学 , Redox Biology , Vascular Biology

Research theme for competitive and other funds (16)：

2016 - 2019 Clarification of new oxidative signaling involved in tissue fibrogenesis and its application to therapeutic strategy
2013 - 2016 A study on signaling pathways associated with NOX4/NADPH oxidase for the development of new antifibrotic drugs
2012 - 2016 Development of a new NOX1-targeted strategy for the treatment of metabolic syndrome
2011 - 2012 A study on the role of NOX1/NADPH oxidase in cardiac arrhythmia
2008 - 2010 Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

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Papers (97)：

Misaki Matsumoto, Hikari Sawada, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Masato Katsuyama, Kaori Shintani-Ishida, Hiroshi Ikegaya, Shigehiko Takegami, Atsushi Umemura, et al. Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection. Frontiers in medicine. 2022. 9. 941180-941180
Misaki Matsumoto, Junjie Liu, Kazumi Iwata, Masakazu Ibi, Nozomi Asaoka, Xueqing Zhang, Masato Katsuyama, Masaya Matsuda, Takeshi Nabe, Katrin Schröder, et al. NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis. Journal of Pharmacological Sciences. 2021. 146. 2. 88-97
Nozomi Asaoka, Masakazu Ibi, Hikari Hatakama, Koki Nagaoka, Kazumi Iwata, Misaki Matsumoto, Masato Katsuyama, Shuji Kaneko, Chihiro Yabe-Nishimura. NOX1/NADPH Oxidase Promotes Synaptic Facilitation Induced by Repeated D2 Receptor Stimulation: Involvement in Behavioral Repetition. The Journal of Neuroscience. 2021. 41. 12. 2780-2794
Masato Katsuyama, En Kimura, Masakazu Ibi, Kazumi Iwata, Misaki Matsumoto, Nozomi Asaoka, Chihiro Yabe-Nishimura. Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells. Archives of toxicology. 2021. 95. 1. 135-148
Xueqing Zhang, Masakazu Ibi, Ryu Haga, Kazumi Iwata, Misaki Matsumoto, Nozomi Asaoka, Junjie Liu, Masato Katsuyama, Chihiro Yabe-Nishimura. NOX1/NADPH oxidase affects the development of autism-like behaviors in a maternal immune activation model. Biochemical and Biophysical Research Communications. 2021. 534. 59-66

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MISC (71)：

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Patents (1)：

虚血又は虚血再灌流によって起こる心機能障害若しくは心筋障害の予防又は治療剤

Education (1)：

- 1980 Kyoto Prefectural University of Medicine

Professional career (1)：

Doctor of Medicine (Kyoto Prefectural University of Medicine)

Work history (1)：

1988 - 1996 国立小児病院小児医療研究センター

Committee career (4)：

日本臨床薬理学会評議員
日本神経化学会評議員
日本糖尿病学会評議員
日本薬理学会評議員

Awards (2)：

1998 - 日本糖尿病合併症学会Young Investigator Award
1997 - 日本薬理学会学術奨励賞

Association Membership(s) (5)：

日本臨床薬理学会 , 日本糖尿病合併症学会 , 日本神経化学会 , 日本糖尿病学会 , 日本薬理学会

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