Research theme for competitive and other funds (28)：
2020 - 2024 A mechasism for bovine maternal immune tolerance toward pregnancy via sensing sperm and embryo
2019 - 2022 アミノ酸プロファイルによる不受胎牛判別
2016 - 2020 Immune system of oviduct for very early pregnancy in dairy cattle: A crostalk between sperm/embryo and immune cells
2016 - 2020 妊娠のための子宮内環境の構築と再構築
2016 - 2018 Biology of Trophoblast Cell Fusion
2015 - 2018 Maternal immune strategy to recognize conceptus in mammals
2016 - 2018 不受胎牛の早期判別と分娩間隔短縮
2013 - 2016 Epigenetic regulation of placentation
2013 - 2016 インターフェロンとその関連因子による妊娠補助剤と抗ウイルス療法の開発
2011 - 2014 Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation
2008 - 2012 寄生ゲノムのダイナミズム:レトロエレメントの制御と高度利用
2008 - 2012 妊娠の制御と成立機構のリモデリング
2004 - 2007 インターフェロン遺伝子発現制御による着床と妊娠の成立
2005 - 2006 着床・胎盤形成制御の新規遺伝子Hβ58の解析
2001 - 2004 Selection of mastitis-resistant cows using the production of L-amino acid oxidase
2002 - 2003 Mechanism of killing bacteria, expression of gene encoded enzyme and its genetics
2001 - 2002 Use of interferon-τ for generation of viral resistant animals.
2001 - 2002 Analysis for putative relationship between causative genes for hereditary disorder and quantitative traits loci in cattle
2000 - 2001 The relationship between the poly(A) tail of casein mRNA and the ageing of the mammary gland
1999 - 2001 Establishment of recombinant gonadotropin-producing system by making use of E. coli ahd cloned aninals.
1998 - 2000 Interferon-tau and implantation : Prevention of early pregnancy losses.
1998 - 1999 THE RELATIONSHIP BETWEEN MAMMARY GROWTH AND LACTATIONAL ACTIVITY AT THE MOLECULAR LEVEL
インターフェロン発現による抗病性動物の作出
インターフェロン・タウ遺伝子の発現制御機構の解析
妊娠・着床の生物学:胚の死滅防止へ向けて
IFN expression and viral resistant animals
Regulation of interferon-tau gene expression
Biology of implantation : Prevention of embryonic loss
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Papers (209)：
Toshihiro Sakurai, Kazuya Kusama, Kazuhiko Imakawa. Progressive Exaptation of Endogenous Retroviruses in Placental Evolution in Cattle. Biomolecules. 2023. 13. 12
Keigo Nakamura, Kazuya Kusama, Masatoshi Hori, Kazuhiko Imakawa. Global analyses and potential effects of extracellular vesicles on the establishment of conceptus implantation during the peri-implantation period. The Journal of reproduction and development. 2023. 69. 5. 246-253
Toshiaki Inenaga, Koh Fukuoka, Mikiya Sumida, Sakiko Aiba, Kohei Nishikaku, Yuta Matsuno, Tomoko Kobayashi, Kazuhiko Imakawa. Low proviral load in the Kumamoto strain of Japanese Brown cattle infected with the bovine leukemia virus. BMC Veterinary Research. 2023. 19. 1
Rulan Bai, Kazuya Kusama, Yuta Matsuno, Hanako Bai, Toshihiro Sakurai, Koji Kimura, Kazuhiko Imakawa. Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period. Frontiers in endocrinology. 2023. 14. 1075030-1075030
Md Belal Hossain, Tomoko Kobayashi, Sakurako Makimoto, Misaki Matsuo, Kohei Nishikaku, Benjy Jek Yang Tan, Akhinur Rahman, Samiul Alam Rajib, Kenji Sugata, Nagaki Ohnuki, et al. Clone Dynamics and Its Application for the Diagnosis of Enzootic Bovine Leukosis. Journal of Virology. 2022
Regulation of cytokines during peri-implantation periods in ruminant ungulates. (共著)
The 1998 Congress of the International Society for Animal Clinical Biochemistry. 1998
Regulation of interferon-tau expression. (共著)
In Biology of Pregnancy, Eighth Sirakaba conference 1996, Tokyo, Japan 1997
Identification and cellular localization of human placental interferon. (共著)
In : Early Embryo Development, Uterus Preparation and Role of Cytokines in Implantation and Labour, G Chaouat(ed) 1995
Cytokines as mediators of pregnancy specific interferon, ovine trophoblast protein-1. (共著)
Endocrinology of Embryo-Endometrial Interactions, SR Glasser(ed) 1994
1986 - 1989 University of Missouri Department of Animal Sciences
- 1984 ネブラスカ州立大学大学院 畜産学研究科 繁殖内分泌学
- 1984 University of Nebraska U. S. A. Graduate School, Division of Animal Sciences Reproductive Endocrinology
- 1975 Ibaraki University College of Agriculture
- 1975 Ibaraki University Faculty of Agriculture
Professional career (1)：
Ph.D. (University of Nebraska (U. S. A))
Work history (8)：
2020/04 - 現在 Tokai University Research Institute of Agriculture Executive Director
2018/04 - 現在 Tokai University Research Institute of Agriculture Professor
2016/09 - 2018/03 The University of Tokyo Professor
1997/03 - 2016/08 The University of Tokyo Graduate School of Agricultural and Life Sciences Associate Professor
1995 - 1997 University of Kansas Medical Center Department of Pathlogy and Laboratory Medicine Associate professor
1995 - 1997 Univ of Kansas medical Center. Dept of
1989 - 1995 University of Kansas School of Medicine Assistant Professor
1989 - 1995 Univ of Kansas Sch. of med-wichita, Dept
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Committee career (9)：
2010/05 - 現在 Society for the Study of Reproduction Program/International relations
2009/09 - 現在 日本獣医学会 評議員
2002/04 - 現在 日本生殖内分泌学会 評議員
1997/04 - 現在 日本内分泌学会 評議員
1997/07 - 2019/03 日本繁殖生物学会 評議員
2013/04 - 2015/03 関東畜産学会 学会長
2011/04 - 2012/03 日本畜産学会 監事
1998 - 日本繁殖生物学会 評議員
1998 - The Japanese Society of Animal Reproduction Advisory Board
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Association Membership(s) (9)：
Society for the Study of Reproduction
, KANTO SOCIETY OF ANIMAL SCIENCE
, JAPAN SOCIETY OF FERTILIZATION AND IMPLANTATION
, 日本生殖内分泌学会
, THE JAPAN ENDOCRINE SOCIETY
, JAPANESE SOCIETY OF VETERINARY SCIENCE
, JAPANESE SOCIETY OF ANIMAL SCIENCE
, SOCIETY FOR REPRODUCTION AND DEVELOPMENT
, The Japanese Society of Animal Reproduction
