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J-GLOBAL ID：200901031272190624   Update date: Sep. 29, 2024

Okajima Takaharu

オカジマ タカハル | Okajima Takaharu
Affiliation and department：
Hokkaido University

About Hokkaido University


Job title： Professor
Homepage URL  (2)： http://www.ist.hokudai.ac.jp/labo/cell/ ,  http://cell-c.ist.hokudai.ac.jp/
Research field  (5)： Biophysics ,  Applied physics - general ,  Bio-, chemical, and soft-matter physics ,  Nanobioscience ,  Nanomaterials
Research keywords  (6)： 応用物理学一般 ,  生物物理学 ,  バイオナノテクノロジー ,  Polymer Science ,  Biophysics ,  Bionanotechnology
Research theme for competitive and other funds  (29)：
  • 2022 - 2028 階層性自己組織化複合材料デザイン(代表者:松本卓也)
  • 2021 - 2024 原子間力顕微鏡による1細胞診断技術の高速化
  • 2021 - 2023 The establishment of tissue elasticity modalities and aging control
  • 2021 - 2023 原子間力顕微鏡を用いた発生胚メカニクスの包括的マッピング計測技術の開発
  • 2019 - 2022 In vitro pharmacological assessment of pulmonary arterial hypertension by atomic force microscopy
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Papers (78)：
  • K. Shigemura, K. Kuribayashi-Shigetomi, R. Tanaka, H. Yamasaki, T. Okajima. Mechanical properties of epithelial cells in domes investigated using atomic force microscopy. Frontiers in Cell and Developmental Biology. 2023. 11. 1245296
  • T. Okajima, K. Kuribayashi-Shigetomi. Atomic force microscopy for investigating cell and tissue mechanics as heterogeneous and hierarchical materials, Journal of Biomechanical Science and Engineering. Journal of Biomechanical Science and Engineering. 2023
  • Hirofumi Tsuru, Chika Yoshihara, Hidehiro Suginobe, Mizuki Matsumoto, Yoichiro Ishii, Jun Narita, Ryo Ishii, Renjie Wang, Atsuko Ueyama, Kazutoshi Ueda, et al. Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy. Journal of the American Heart Association. 2023. e029676
  • Mizuki Matsumoto, Hirofumi Tsuru, Hidehiro Suginobe, Jun Narita, Ryo Ishii, Masaki Hirose, Kazuhisa Hashimoto, Renjie Wang, Chika Yoshihara, Atsuko Ueyama, et al. Atomic force microscopy identifies the alteration of rheological properties of the cardiac fibroblasts in idiopathic restrictive cardiomyopathy. PloS one. 2022. 17. 9. e0275296
  • Shinichi Katsuragi, Nao Tatsumi, Mizuki Matsumoto, Jun Narita, Ryo Ishii, Hidehiro Suginobe, Hirofumi Tsuru, Renjie Wang, Shigetoyo Kogaki, Ryosuke Tanaka, et al. Pharmacological Alteration of Cellular Mechanical Properties in Pulmonary Arterial Smooth Muscle Cells of Idiopathic Pulmonary Arterial Hypertension. Cardiology Research. 2021. 12. 4. 231-237
ｍore...
MISC (9)：
  • Yusuke Mizutani, Zen Ishikura, Myung-Hoon Choi, Sang-Joon Cho, Takaharu Okajima. Nanoscale Cell Membrane Fluctuations Measured by Scanning Ion Conductance Microscopy. BIOPHYSICAL JOURNAL. 2013. 104. 2. 317A-317A
  • MIZUTANI Yusuke, PINGGEN Cai, TSUCHIYA Masahiro, OKAJIMA Takaharu. OS1103 Mechanical properties of living cells in transient-state by atomic force microscopy. 2012. 2012. "OS1103-1"-"OS1103-2"
  • MIZUTANI Yusuke, TSUCHIYA Masahiro, KAWAHARA Koichi, OKAJIMA Takaharu. 1101 Spontaneously Beating Cardiomyocytes Investigated by AFM. 2010. 2009. 22. 187-187
  • Wagatsuma K., Niikura K., Kamitani R., Haruna Y., Mizutani Y., Tokumoto H., Kawahara K., Okajima T. 25pPSB-58 Measurement of the Diffusion Process of Living Cell by Fluorescence Correlation Spectroscopy. Meeting abstracts of the Physical Society of Japan. 2008. 63. 1. 384-384
  • Kawauchi Yasunori, Tanaka Yoshimi, Furukawa Hidemitsu, Okajima Takaharu, Na Yang-Ho, Kurokawa Takayuki, Gong Jian Ping, Osada Yoshihito. 20pPSA-44 Soft & Wet Matter With Ultra Toughness (2) : Necking Phenomenon in DN gels. Meeting abstracts of the Physical Society of Japan. 2007. 62. 1. 366-366
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Patents (9)：
  • 原子間力顕微鏡による単一細胞の力学的診断方法と診断装置
  • 酵母細胞の力学特性の測定方法、及び力学特性に基づいた酵母細胞のスクリーニング方法
  • 細胞足場材料、細胞モデル、及び細胞足場材料の製造方法
  • 細胞の複素弾性率の計測方法および計測システム
  • 単一細胞の力学特性の計測方法および計測装置
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Books (28)：
  • 原子間力顕微鏡による発生胚皮質領域の力学測定
    膜、47、269-272(2022). 2022
  • 原子間力顕微鏡:多細胞系の力学物性計測の現状
    2022
  • ナノ計測 : 電子線・光・プローブ技術を用いたナノ・バイオ材料の探索と評価
    近代科学社 2020 ISBN:9784764950290
  • 原子間力顕微鏡法:細胞表面近傍のナノメカニクス
    表面と真空、63、437-440 (2020) 2020
  • AFMによる多細胞系の力学測定
    高分子、68、656-657 2019
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Lectures and oral presentations  (17)：
  • Mapping mechanical properties of single cells during embryogenesis using atomic force microscopy
    (AFM BioMED conference, (2022.8.29-9.2, Okazaki) 2022)
  • 多細胞メカニクスの時空間マッピング測定
    (ナノプローブテクノロジー第167委員会 第103回研究会、高分子×SPM(2022.7.27、大岡山) 2022)
  • 原子間力顕微鏡による発生胚の力学動態の計測
    (第61回日本生体医工学会、細胞アッセイ:細胞動態の把握と計測、(2022.6.28-30、新潟) 2022)
  • 発生胚表面のメカニクス:原子間力顕微鏡測定
    (日本膜学会の第44回年会、(2022.6.9-10、早稲田) 2022)
  • Nanomechanics of single cells and tissues revealed by atomic force microscopy
    (Pacifichem 2021, Experimental and Computational Analysis of the Nano-Bio Interface for Sustainable Nanotechnology, (Dec.16-21, 2021, Online) 2021)
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Education (2)：
  • - 1993 Tokyo Institute of Technology Science of Engineering
  • - 1991 Yokohama City University
Professional career (1)：
  • Ph.D. (Tokyo Institute of technology)
Work history (6)：
  • 2019/04 - 現在 Hokkaido University
  • 2013/05 - 2019/03 Hokkaido University Graduate School of Information Science and Technology
  • 2007/04 - 2013/04 Hokkaido University Graduate School of Information Science and Technology
  • 2003/04 - 2007/03 Hokkaido University Research Institute for Electronic Science, Nanotechnology Research Center
  • 1998/04 - 2003/03 Tokyo Institute of Technology Bioscience and Biotechnology
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Association Membership(s) (5)：
American Society for Cell Biology ,  表面科学会 ,  日本生物物理学会 ,  応用物理学会 ,  Biophysical Society(米国)
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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