Rchr
J-GLOBAL ID：200901031276405641   Update date: Sep. 20, 2024

Yamashita Naoya

ヤマシタ ナオヤ | Yamashita Naoya
Affiliation and department：
Kanagawa Institute of Technology Faculty of Applied Bioscience Department of Applied Bioscience

About Kanagawa Institute of Technology Faculty of Applied Bioscience Department of Applied Bioscience


Job title： Associate Professor
Other affiliations (1)：
Homepage URL  (1)： http://pharmacology.sakura.ne.jp/index.html
Research field  (2)： Neuroscience - general ,  Neuroanatomy and physiology
Research keywords  (9)： axonal transport ,  神経栄養因子 ,  シグナル伝播 ,  セマフォリン ,  ドーパミン作動性ニューロン ,  脳の性分化 ,  前腹側脳室周囲核 ,  ノックアウトマウス ,  CRMP4
Research theme for competitive and other funds  (8)：
  • 2020 - 2023 軸索輸送を介した逆行性シグナル伝達とそのアルツハイマー病発症への関与
  • 2012 - 2015 Elucidation of Sema3A signaling pathway in mechanisms of neuropathic pain
  • 2012 - 2015 Interaction of CRMP1 and Filamin-A regulates F-actin-cytoskeleton.
  • 2012 - 2012 The role of the trafficking of PlexinA4-containing vesicles in dendritic development
  • 2010 - 2012 The role of Collapsin Response Mediator Protein 4(CRMMP4) in sexual differentiation of the brain
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Papers (62)：
  • Mao Hayashi, Yoshinari Wada, Akira Yamamura, Hideki Inoue, Naoya Yamashita, Shigetoshi Ichimura, Yasuhiro Iida. Evaluation of the enzymatic properties of DNA (cytosine-5)-methyltransferase M.ApeKI from archaea in the presence of metal ions. Bioscience, biotechnology, and biochemistry. 2024
  • Blaine Connor, Guillermo Moya-Alvarado, Naoya Yamashita, Rejji Kuruvilla. Transcytosis-mediated anterograde transport of TrkA receptors is necessary for sympathetic neuron development and function. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 6. e2205426120
  • Blaine Connor, Naoya Yamashita, Rejji Kuruvilla. Transcytosis-mediated anterograde transport of TrkA receptors is necessary for sympathetic neuron development and function. 2022
  • Munetaka Nomoto, Glenn T Konopaske, Naoya Yamashita, Reina Aoki, Aoi Jitsuki-Takahashi, Haruko Nakamura, Hiroko Makihara, Mari Saito, Yusuke Saigusa, Fumio Nakamura, et al. Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 31
  • Aoi Jitsuki-Takahashi, Susumu Jitsuki, Naoya Yamashita, Meiko Kawamura, Manabu Abe, Kenji Sakimura, Akane Sano, Fumio Nakamura, Yoshio Goshima, Takuya Takahashi. Activity-induced secretion of semaphorin 3A mediates learning. The European journal of neuroscience. 2021. 53. 10. 3279-3293
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MISC (58)：
  • Sugiyama Rei, Ke-Yi Lin, Fumio Nakamura, Takashi Sakurai, Yoshio Goshima, Naoya Yamashita. Construction of the ELISA assay to quantify Semaphorin 3A in the adult brain. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2023. 97. 2-B
  • 山下直也. Sema3Aをターゲットとした新規アルツハイマー病診断法の確立とその治療法への応用. 冲中記念成人病研究所年報. 2023. 49
  • 関口拓己, 櫻井隆, 山下直也. Aβ産生制御におけるAPP-PlexinAシグナルの機能解析. 日本薬理学雑誌. 2023. 158. Supplement
  • Furukawa Suzuna, Kobayashi Mizuki, Lin Ke-Yi, Nakamura Fumio, Sakurai Takashi, Goshima Yoshio, Yamashita Naoya. Construction of the ELISA assay to quantify Semaphorin 3A in the adult brain. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 3-B-P-236
  • Sekiguchi Takumi, Sakurai Takashi, Yamashita Naoya. Potential effects of Semaphorin3A-PlexinA signaling on the function and metabolism of amyloid-beta precursor protein. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 4-B-P-301
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Patents (3)：
Books (1)：
  • CRMP family protein: Novel targets for Cdk5 that regulates axon guidance, synapse matuation, and cell migration.
    Springer Science 2008
Lectures and oral presentations  (13)：
  • Axonal transport through signaling endosome and its roles in neurodegenerative disorders
    (The 92nd Annual Meeting of the Japanese Pharmacological Society 2019)
  • A retrograde axonal transport elicited by Semaphorin3A drives AMPA receptor subunit GluA2 to dendrites
    (2013)
  • Semaphorin3AはCdk5を介したCRMP1のリン酸化によりスパインの形態を制御する
    (International meeting for Asian young researchers 2008)
  • Semaphorine3Aはシグナル伝達に関与する分子の軸索内輸送を選択的に亢進する
    (第81回日本薬理学会年会 2008)
  • Regulation of spine development by Semaphorin3A through phosphorylation of CRMP1 by Cdk5.
    (2008)
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Education (5)：
  • 2004 - 2008 Yokohama City University
  • - 2008 Yokohama City University Graduate School, Division of Medicine
  • 2002 - 2004 University of Tsukuba
  • 1998 - 2002 University of Tsukuba
  • - 2002 University of Tsukuba Second Cluster of College
Professional career (2)：
  • 理学修士 (筑波大学)
  • 医学博士 (横浜市立大学)
Work history (8)：
  • 2021/09 - 現在 Juntendo University Faculty of Medicine
  • 2021/09 - 現在 Kanagawa Institute of Technology Faculty of Applied Bioscience Department of Applied Bioscience Associate Professor
  • 2014/04 - 現在 Yokohama City University Graduate School of Medicine Molecular Pharmacology and Neurobiology visiting lecturer
  • 2020/07 - 2021/08 Juntendo University School of Medicine Department of Pharmacology Junior associate professor
  • 2017/07 - 2020/06 Juntendo University School of Medicine, Department of Pharmacology Assistant Professor
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Awards (16)：
  • 2022/10 - 内藤記念科学振興財団 奨励金・研究助成
  • 2022/04 - 冲中記念成人病研究所 研究助成金
  • 2022/03 - ライフサイエンス振興財団 研究助成金
  • 2019/12 - Daiichi Sankyo Foundation of Life Science a grant for medical research
  • 2018/12 - Journal of Pharmacological Sciences 34th Young Researcher's Award
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Association Membership(s) (3)：
Society for Neuroscience ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  JAPANESE SOCIETY OF NEUROLOGY
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