Rchr
J-GLOBAL ID：200901031572113559   Update date: Nov. 20, 2024

Watanabe Mikio

ワタナベ ミキオ | Watanabe Mikio
Affiliation and department：
Osaka University Graduate School of Medicine, Department of Clinical Laboratory and Biomedical Sciences

About Osaka University Graduate School of Medicine, Department of Clinical Laboratory and Biomedical Sciences


Job title： Professor
Other affiliations (1)：
  • Osaka University  Graduate School of Medicine, Center for Twin Research   Professor
Research field  (6)： Internal medicine - General ,  Genetics ,  Metabolism and endocrinology ,  Other ,  Healthcare management, medical sociology ,  Immunology
Research keywords  (20)： 後天性遺伝要因 ,  遺伝子多型 ,  一卵性双生児 ,  予後 ,  検査 ,  妊娠 ,  甲状腺 ,  予防医学 ,  臨床検査医学 ,  内分泌学 ,  臨床免疫学 ,  内科学 ,  epigenetics ,  gene polymorphism ,  Identical Twin ,  Internal Medicine ,  Clinical Immunology ,  Endocrinology ,  Preventive Medicine ,  Clinical Laboratory Science
Research theme for competitive and other funds  (20)：
  • 2022 - 2025 Explication of Interaction between Genetic Factors of Physical Activity and Neighborhood Walkability Using the Twin Study
  • 2022 - 2024 Longitudinal study of oral health and systemic disease in older identical twins
  • 2019 - 2023 Collaboration and comparison on twin analysis of genomic/epigenomic information and common diseases: Hungary and Japan
  • 2019 - 2023 双生児のエピゲノム情報と臨床検査値に基づいた、生活習慣病に影響する環境因子の解明
  • 2017 - 2020 Development of the diagnostic methods to predict the development and the prognosis of autoimmune diseases based on the genome and epigenome informations
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Papers (188)：
  • Saho Mori, Yuya Arakawa, Mika Hasegawa, Shiho Kato, Hinako Hashimoto, Saki Yoshioka, Hiromichi Ueda, Osaka Twin Research Group, Mikio Watanabe. Genetic and epigenetic factors affecting carotid intima-media thickness in monozygotic twins. Gene. 2025. 936. 149093-149093
  • Yoichi Takenaka, Osaka Twin, Research Group, Mikio Watanabe. Development of Index to Measure the Strength of Environmental Factors on DNA Methylation in Identical Twins Authors. Epigenomes (in press). 2024
  • Hiroki Ohtani, Naoya Inoue, Yoshinori Iwatani, Yuri Takeno, Yuya Arakawa, Yoh Hidaka, Mikio Watanabe. Effect of DNA methylation at the CTLA4 gene on the clinical status of autoimmune thyroid diseases. Clinical Immunology. 2024. 267. 110338-110338
  • Kenichi Yamamoto, Yoko Lee, Tatsuo Masuda, Keiichi Ozono, Yoshinori Iwatani, Mikio Watanabe, Yukinori Okada, Norio Sakai. Functional landscape of genome-wide postzygotic somatic mutations between monozygotic twins. DNA Research. 2024. 31. 5. dsae028
  • Riku Kinoshita, Naoya Inoue, Yoshinori Iwatani, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe. Methylation levels of the IL10 gene in peripheral blood are related to the intractability of Graves' disease. Clinical Immunology. 2024. 263. 110196-110196
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MISC (228)：
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Books (12)：
  • ここからはじめる 臨床検査技師国家試験ファーストトレーニング 令和3年版国家試験出題基準対応
    2022 ISBN:9784263226940
  • MicroRNA as Disease Biomarkers and Its Applications for Medical Diagnosis
    2022 ISBN:9784781316673
  • クエスチョン・バンク臨床検査技師国家試験問題解説
    メディックメディア 2021 ISBN:9784896328394
  • 臨床検査法提要 改訂第35版
    金原出版 2020 ISBN:9784307050531
  • DNA and Histone Methylation as Cancer Targets (Cancer Drug Discovery and Development) - Chapter 2 - The molecular basis of DNA methylation.
    Humana Press 2017 ISBN:3319597841
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Lectures and oral presentations  (5)：
  • 教育講演2「ふたご研究に秘められた可能性」
    (第71回日本医学検査学会 2022)
  • Genetic and epigenetic approarches to autoimmune thyroid diseases, International molecular thyroidlogy sympojium
    (The 64th Annual meeting of Japan Thyroid Association 2021)
  • Plenary Lecture, Genetics of Thyroid Autoimmunity
    (The 16th International Thyroid Congress (ITC) 2020)
  • ふたごを対象としたエピゲノム研究、シンポジウム「エピゲノム情報を利用した新たな疾患像の理解と医療応用に向けて」
    (日本人類遺伝学会第65回大会 2020)
  • 受賞講演「臨床検査へのゲノム・エピゲノム情報の応用」
    (第58回日本臨床化学会年次学術集会 2018)
Works (7)：
  • 一卵性双生児を対象とし後天的遺伝要因に着目した自己免疫疾患予後予測検査法の開発
    2009 -
  • 末梢性自己寛容誘導機序の改名に基づく自己免疫疾患の発症予知診断法の開発
    2008 -
  • 甲状腺疾患をモデルとした自己免疫疾患予後予測検査法の開発
    2004 -
  • 「緑地の有するストレス緩和・医療的効果を考慮に入れたランドスケープ計画に関する研究」
    2003 -
  • 「都市公園の植栽デザインの違いによる人間の心理的・生理的反応特性に関する基礎的研究」
    2002 -
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Education (2)：
  • 1993 - 1997 Osaka University Graduate School of Medicine Course of Internal Medicine
  • 1987 - 1993 Osaka University Faculty of Medicine Medical School
Professional career (2)：
  • Doctor of Medical Science (D.Msc., Ph.D.) (Osaka University)
  • Bachelor of Medicine (Osaka University)
Work history (11)：
  • 2023/04 - 現在 Osaka University Graduate School of Medicine Center for Twin Research Director
  • 2019/01 - 現在 Professor
  • 2019/01 - 現在 大阪大学教授(大学院医学系研究科附属ツインリサーチセンター)(兼任)
  • 2012/04 - 2019/01 Associate Professor of Center for Twin Research, Osaka University Graduate School of Medicine
  • 2012/04 - 2019/01 Associate Professor of Osaka University Graduate School of Medicine
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Committee career (18)：
  • 2024/04 - 現在 日本内分泌学会 評議員
  • 2023/06 - 現在 国立大学臨床検査学教育協議会 副理事長
  • 2023/04 - 現在 日本臨床検査医学会近畿支部 幹事
  • 2022/06 - 現在 日本臨床検査医学会 学会賞委員
  • 2022/04 - 現在 Editorial Board of Endocrine Journal
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Awards (10)：
  • 2018/08 - 日本臨床化学会 学術賞
  • 2016/02 - Charitable Trust Laboratory Medicine Research Foundation of Japan Charitable Trust Laboratory Medicine Research Foundation of Japan, 2015 Research grant
  • 2014/07 - American Association for Clinical Chemistry AACC Clinical Diagnostic Immunology Division Poster Award 2014
  • 2014/07 - National Academy of Clinical Biochemistry NACB Distinguished Abstract Award 2014
  • 2012/07 - National Academy of Clinical Biochemistry NACB Distinguished Abstract Award 2012
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Association Membership(s) (16)：
American Thyroid Association ,  Japan Society of Internal Medicine ,  The Japan Society for Clinical Immunology ,  Japanese Society of Laboratory Medicine ,  日本臨床検査学教育学会 ,  The Japanese Society for Epigenetics ,  健康食品管理士会(認定健康食品管理士) ,  Japan Cytometry Society (Certified Cytometrist; CC) ,  Japan Society of Clinical Chemistry (Japan Certified Clinical Chemist; JCCC) ,  Japan Thyroid Association ,  The Japanese Society for Gene Diagnosis and Therapy ,  Japanese Society of Twin Study ,  Interrnational Society for Twin Study ,  Asia & Oceania Thyroid Association ,  American Association for Clinical Chemistry ,  The Japan Endocrine Society (Editorial Board of Endocrine Journal)
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