2011 - 2013 Effect of FAEEs on intracellular signalling
2011 - 2013 Effects of protease-activated receptors (PARs) on intracellular calcium dynamics of acinar cells in rat lacrimal glands.
2009 - 2011 Morphological and functional analysis of protease-activated receptor 2 on intracellular calcium dynamics in rat parotid gland acinar cells
2008 - 2010 Development and application of cAMP imaging in living cell/tissue specimens
2008 - 2010 リアルタイム共焦点レーザー顕微鏡を用いた前立腺のカルシウム動態の解析
2008 - 2010 The establishment of a treatment system using digital imaging analysis on intracellular calcium ion dynamics of golden hamster prostatic smooth muscle cells.
2006 - 2008 Morphological and functional analysis which protein phosphatasesplay a role in regulating the exocrine mechanism
2005 - 2007 Effect of PARs on the smooth muscles of arterioles, analyzing by bioimaging method
1999 - 2002 Visualization of intracellular signalling in living tissue: Application of real-time confocal microscopy
1999 - Digital Imaging Analysis in Neuron and Satellite Cells using a Real-Time Confocal Laser Scanning Microscope
1998 - Digital Imaging Analysis in Arteriole Smooth Muscle Cells using a Real-Time Laser Scanning Confocal Microscope
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Papers (76)：
Sayed Sharif Abdali, Takuya Yokoyama, Yoshio Yamamoto, Keishi Narita, Masato Hirakawa, Tomoyuki Saino. Immunohistochemical analysis and distribution of epithelial mast cells in the rat larynx and trachea. Histochemistry and Cell Biology. 2024
Masato Hirakawa, Takuya Yokoyama, Sayed Sharif Abdali, Yoshio Yamamoto, Tomoyuki Saino. Immunohistochemical localization of proteins involved in exocytosis of glutamate from P2X3 purinoceptor-expressing subserosal afferent nerve endings in the rat gastric antrum. Acta Histochemica. 2024. 126. 4. 152170-152170
Takuya Yokoyama, Tomoyuki Saino, Nobuaki Nakamuta, Yoshio Yamamoto. Immunohistochemical localization of P2Y12 purinoceptors in the rat carotid body. Autonomic Neuroscience. 2024. 103158-103158
Satsuki Maesawa, Takuya Yokoyama, Wakana Sakanoue, Yoshio Yamamoto, Masato Hirakawa, Hirohisa Shiraishi, Kenichi Sato, Tomoyuki Saino. ADP-mediated Modulation of Intracellular Calcium Responses in Chromaffin Cells: The Role of Ectonucleoside Triphosphate Diphosphohydrolase 2 on Rat Adrenal Medulla Function. Journal of Histochemistry & Cytochemistry. 2023. 72. 1. 41-60
Naoto Yoshino, Takuya Yokoyama, Hironori Sakai, Ikumi Sugiyama, Takashi Odagiri, Masahiro Kimura, Wataru Hojo, Tomoyuki Saino, Yasushi Muraki. Suitability of Polymyxin B as a Mucosal Adjuvant for Intranasal Influenza and COVID-19 Vaccines. Vaccines. 2023. 11. 11. 1727-1727
Mutations of Arginine-198 in Sarcoplasmic Reticulum Ca<sup>2+</sup>-ATPase Cause Inhibition of Hydrolysis of the Phosphoenzyme Intermediate formed from Inorganic Phosphate.(jointly worked)
Elsevier Science B.V. 2000
Deletions or Specific Substitutions of a Few Residues in the NH<sub>2</sub>-terminal Region Ala3-Thr9 of Sarcoplasmic Reticulum Ca<sup>2+</sup>-ATPase Cause Inactivation and Rapid Degradation of the Enzyme Expressed in COS-1 Cells.(jointly worked)
Elsevier Science B.V. 2000
The investigation of the distribution of autonomic nerves on superior tarsal plate.
(International council of ophthalmology, World ophthalmology congress. 2018)
Intracellular Calcium Dynamics and Expression of P2Y and IP3 Receptors in a Cycling G1-phase cell.
(Japanese Association of Anatomists (JAA) The 62nd annual meeting of Tohoku and Hokkaido Regions 2016)
α1-Adrenoceptors relate Ca2+ modulation and mucin secretion in rat lacrimal grand.
(The 120th Anuual Meeting of The Japanese Association of Anatomists and the 92nd Annual Meeting of the Physiological Society of Japan 2015)
Effects of protease-activated receptors (PARs) on intracellular calcium dynamics of acinar cells in rat lachrimal glands.
(International Symposium Anatomical Science for advance in health and clinical therapy 2013)
Protease-activated receptor 2 affects protein secretion through a multifunctional Ca2+/calmodulin-dependent protein kinase (CAMK II) pathway in rat parotid gland acinar cells.
(FAOBMB Mini-Symposium - Molecular Bases for Medical and Pharmaceutical Sciences - 2013)
1985 - 1991 Asahikawa Medical University School of Medicine Medical Course
Professional career (1)：
MD. Ph D.
Work history (8)：
2014/04 - 現在 Iwate Medical University Department of Anatomy (Cell Biology) Professor
2008 - 2014 Iwate Medical University School of Medicine
2007 - 2008 Iwate Medical University School of Medicine
2006 - 2007 Iwate Medical University School of Medicine
1998 - 2006 Iwate Medical University School of Medicine
2004/04 - 2005/11 Research associate of the Department of Oral Biology, School of Dentistry, University of Washington
1994/10 - 1998/03 Asahikawa Medical University
1994 - 1998 Asahikawa Medical College, Graduate School of Medicine
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Committee career (10)：
2022/04 - 現在 岩手県立大学 非常勤講師
2022/04 - 現在 盛岡第一高校学校運営協議会委員
2019/04 - 現在 The medical association of Iwate Medical University Vice-president
2019/04 - 現在 Anatomical Science International Managing Editor
2014/12 - 現在 日本バイオイメージング学会 評議員
2011/04 - 現在 日本解剖学会 学術評議員
2020/06 - 2022 盛岡第一高校学校学外評価委員
2017/04 - 2019/03 日本解剖学会医療専門職教育委員会委員長
2008/06 - 2019/03 岩手医科大学医師会 理事
2016 - 2019 盛岡第一高校スーパーグローバルハイスクール 外部委員
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Awards (3)：
2006 - 第21回日本顕微鏡学会論文賞
2004 - 第3回インテリジェント・コスモス奨励賞
2003 - 岩手医科大学圭陵会学術賞
Association Membership(s) (10)：
歯科麻酔学会
, THE JAPAN SOCIETY FOR MEDICAL EDUCATION
, JAPANESE SOCIETY FOR MICROCIRCULATION
, The Japanese Molecular Biological Society
, 日本顕微鏡学会
, The American Society for Cell Biology
, The Japanese BioImaging Society
, The Japanease Association of Anatomists
, The Japanese Biochemical Society
, The Japanese Pediatric Society
